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Published in: Colloid and Polymer Science 1/2014

01-01-2014 | Short Communication

Silica nanocapsules for redox-responsive delivery

Authors: Johannes Fickert, David Schaeffel, Kaloian Koynov, Katharina Landfester, Daniel Crespy

Published in: Colloid and Polymer Science | Issue 1/2014

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Abstract

Redox-responsive silica nanocapsules with a hydrophobic liquid core were synthesized by reactive templating of miniemulsion droplets with functional alkoxysilanes. Tetrasulfide bridges were successfully introduced into the inorganic shell and were found to be accessible for chemical reactions as shown by 31P-NMR spectroscopy. Indeed, the tetrasulfide groups could be reduced to yield thiol groups. A subsequent increase of permeability of the silica shell was observed upon reduction of the tetrasulfide groups.

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Appendix
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Metadata
Title
Silica nanocapsules for redox-responsive delivery
Authors
Johannes Fickert
David Schaeffel
Kaloian Koynov
Katharina Landfester
Daniel Crespy
Publication date
01-01-2014
Publisher
Springer Berlin Heidelberg
Published in
Colloid and Polymer Science / Issue 1/2014
Print ISSN: 0303-402X
Electronic ISSN: 1435-1536
DOI
https://doi.org/10.1007/s00396-013-3105-8

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