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Journal of Materials Science

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01-06-2018 | Mechanochemical Synthesis

Studies on the mechanochemical Knoevenagel condensation of fluorinated benzaldehyde derivates

Authors: Sebastian Haferkamp, Werner Kraus, Franziska Emmerling

Published in: Journal of Materials Science | Issue 19/2018

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Abstract

The mechanochemical Knoevenagel condensation of three fluorinated benzaldehyde derivates and malononitrile was investigated. The reactions were performed under solvent- and catalyst-free conditions and resulted in highly crystalline products after crystallization from a viscous phase in the milling jar. The quality of the obtained crystals was sufficient for single-crystal X-ray diffraction circumventing a recrystallization step. To gain more information on the reaction, progress was investigated in situ using time-resolved Raman spectroscopy. The results show a direct conversion of the reactants.

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Title: Studies on the mechanochemical Knoevenagel condensation of fluorinated benzaldehyde derivates
Authors: Sebastian Haferkamp
Werner Kraus
Franziska Emmerling
Publication date: 01-06-2018
Publisher: Springer US
Published in: Journal of Materials Science / Issue 19/2018
Print ISSN: 0022-2461
Electronic ISSN: 1573-4803
DOI: https://doi.org/10.1007/s10853-018-2492-0

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