Synthesis and application of silica hybrids grafted with new guanidine-containing polymers as highly effective adsorbents for bilirubin removal

The development and design of adsorbents with high adsorption performance is the actual aim for successful toxin removal. In this work, we report the performance of new guanidine-containing polymers as a shell orientated around silica particles with following application for effective bilirubin removal. To evaluate polymer-shell modification, Fourier transform infrared spectroscopy and high-resolution electron microscopy were performed. Changes in surface morphology of polymer-coated silicas were detected. It was shown that polymeric shell completely covers silica surface. The grafting amount was evaluated by thermogravimetric and was in 18–34 % range. Incorporation of guanidine containing polymers into silica matrix leads to the great increase in adsorption capacity According to the Langmuir model, the maximum adsorption capacity for bilirubin was 43.47 mg/g. We also demonstrated that prepared polymer-coated silicas could well adsorb bilirubin from the bilirubin-albumin solution at low concentration of albumin. Therefore, this study revealed that guanidine-containing polymers have great potential to serve as effective agents for improving of the adsorbent for bilirubin removal.