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Colloid and Polymer Science
Published in: Colloid and Polymer Science 6/2015

01-06-2015 | Original Contribution

Synthesis and properties of the antibacterial hydrogels with enhanced mechanical strengths

Authors: Qin Liu, Xiufang Wen, Shouping Xu, Pihui Pi, Jiang Cheng, Renchang Zeng

Published in: Colloid and Polymer Science | Issue 6/2015

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Abstract

A series of cationic poly(hydroxyethyl methacrylate)-g-poly(carboxybetaine methacrylate ester) (PHEMA-g-PCBMAE) hydrogels (HCGs) were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization. The HCGs were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and swelling behaviors. It was found that the HCG hydrogels showed enhanced mechanical strengths compared with PCBMAE hydrogel. In addition, it was observed that the cationic HCGs exhibited excellent antibacterial properties. We found that the equilibrium swelling ratios, mechanical properties, and drug release behaviors were related to the feed ratios of the gels. The tetracycline hydrochloride (TCHC) release results indicated that the drug released from HCGs could be prolonged by increasing the content of hydroxyethyl methacrylate (HEMA) in the gel networks.
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Metadata
Title
Synthesis and properties of the antibacterial hydrogels with enhanced mechanical strengths
Authors
Qin Liu
Xiufang Wen
Shouping Xu
Pihui Pi
Jiang Cheng
Renchang Zeng
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Colloid and Polymer Science / Issue 6/2015
Print ISSN: 0303-402X
Electronic ISSN: 1435-1536
DOI
https://doi.org/10.1007/s00396-015-3548-1

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