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2011 | OriginalPaper | Chapter

79. Ultrasensitive Detection of Non-amplified Genomic DNA

Authors : Laura Maria Zanoli, Roberta D’Agata, Giuseppe Spoto, Roberto Corradini, Rosangela Marchelli, Cristina Ferretti, Marcello Gatti

Published in: Sensors and Microsystems

Publisher: Springer Netherlands

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Abstract

The combined use of peptide nucleic acid probes and ultrasensitive nanoparticle-enhanced SPRI detection is shown to allow the ultra-sensitive detection of non-amplified genomic DNA.

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Zanoli L, D’Agata R, Spoto G (2008) Surface plasmon-based optical detection of DNA by peptide nucleic acids. Minerva Biotecnologica 20:165–174

D’Agata R, Corradini R, Grasso G, Marchelli R, Spoto G (2008) Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging. ChemBioChem 9:2067–2070CrossRef

D’Agata R, Grasso G, Spoto G (2008) Real-time binding kinetics monitored with surface plasmon resonance imaging in a diffusion-free environment. Open Spectrosc J 1:1–9CrossRef

Germini A, Rossi S, Zanetti A, Corradini R, Corrado F, Marchelli R (2005) Development of a peptide nucleic acid array platform for the detection of genetically modified organisms in food. J Agric Food Chem 53:3958–3962CrossRef

Title: Ultrasensitive Detection of Non-amplified Genomic DNA
Authors: Laura Maria Zanoli
Roberta D’Agata
Giuseppe Spoto
Roberto Corradini
Rosangela Marchelli
Cristina Ferretti
Marcello Gatti
Publisher: Springer Netherlands
Book: Sensors and Microsystems
Print ISBN: 978-94-007-1323-9

Electronic ISBN: 978-94-007-1324-6

Copyright Year: 2011
DOI: https://doi.org/10.1007/978-94-007-1324-6_79