1993 | OriginalPaper | Chapter
Ultraviolet-Induced Immune Suppression and its Relationship to Statospheric Ozone Depletion
Authors : E. C. De Fabo, F. P. Noonan
Published in: The Role of the Stratosphere in Global Change
Publisher: Springer Berlin Heidelberg
Included in: Professional Book Archive
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Ultraviolet radiation-B (280–320nm) is linked directly to skin cancer formation and is also associated with significant immunological alterations leading to local and systemic immunosuppression in mammals. The mechanism as well as the short or long-term effects of such immunological perturbations is largely unknown. This mechanism may, however, play a critical role in human skin cancer development and other UVB-related disorders.