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Journal of Polymer Research
Published in: Journal of Polymer Research 3/2020

01-03-2020 | ORIGINAL PAPER

RETRACTED ARTICLE: A fluorescent Zn(II)-containing coordination polymer for antibiotic sensing and treatment activity on periodontal tissue inflammation after orthodontics by inhibiting the growth of Porphyromonas gingivalis

Authors: Shuqiang Niu, Qianqian Zhang, Yanjun Zang, Fengchun Hou

Published in: Journal of Polymer Research | Issue 3/2020

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Abstract

A novel fluorescent zinc(II)-containing coordination polymer {[Zn(DIPT)](NO3)(H2O)3} (1) having the channel-type framework was generated via using rigid three-terminal nitrogenous hetero-ligand 5-(3,5-di(1H-imidazol-1-yl)phenyl)-2H-tetrazole (HDIPT) in solvent thermal reaction. Benefitting from its excellent fluorescent emission along with high water stability, complex 1 shows selective luminescence sensing for sulfonamide antibiotics with high sensitivity in water. In addition, the anti-bacterial activity of compound 1 against Porphuromonas gingivalis (P. gingivalis ATCC 33277) in vitro and in vivo was evaluated. Firstly, the growth curves of P. gingivalis ATCC 33277 was measured after compound 1 treatment for the in vitro activity evaluation. Then, the in vivo protective effect of compound 1 was further explored, the IL-8 and TNF-α level in gingival fluid revealed the excellent inhibitory effect of compound 1 on the inflammatory response. The results acquired via pose scoring software as well as molecular docking indicated that the compound 1 might bind and inhibit the NF-κB protein function, this might provide a latent regulatory mechanism for compound 1.
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Metadata
Title
RETRACTED ARTICLE: A fluorescent Zn(II)-containing coordination polymer for antibiotic sensing and treatment activity on periodontal tissue inflammation after orthodontics by inhibiting the growth of Porphyromonas gingivalis
Authors
Shuqiang Niu
Qianqian Zhang
Yanjun Zang
Fengchun Hou
Publication date
01-03-2020
Publisher
Springer Netherlands
Published in
Journal of Polymer Research / Issue 3/2020
Print ISSN: 1022-9760
Electronic ISSN: 1572-8935
DOI
https://doi.org/10.1007/s10965-020-2010-3

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