Skip to main content
Top
Published in: International Journal of Computer Assisted Radiology and Surgery 2/2022

03-12-2021 | Original Article

Anisotropic neural deblurring for MRI acceleration

Authors: Maya Mayberg, Michael Green, Mark Vasserman, Dominique Raichman, Eugenia Belenky, Michael Wolf, Shai Shrot, Nahum Kiryati, Eli Konen, Arnaldo Mayer

Published in: International Journal of Computer Assisted Radiology and Surgery | Issue 2/2022

Log in

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

Purpose

MRI has become the tool of choice for brain imaging, providing unrivalled contrast between soft tissues, as well as a wealth of information about anatomy, function, and neurochemistry. Image quality, in terms of spatial resolution and noise, is strongly dependent on acquisition duration. A typical brain MRI scan may last several minutes, with total protocol duration often exceeding 30 minutes. Long scan duration leads to poor patient experience, long waiting time for appointments, and high costs. Therefore, shortening MRI scans is crucial. In this paper, we investigate the enhancement of low-resolution (LR) brain MRI scanning, to enable shorter acquisition times without compromising the diagnostic value of the images.

Methods

We propose a novel fully convolutional neural enhancement approach. It is optimized for accelerated LR MRI acquisitions obtained by reducing the acquisition matrix size only along phase encoding direction. The network is trained to transform the LR acquisitions into corresponding high-resolution (HR) counterparts in an end-to-end manner. In contrast to previous neural-based MRI enhancement algorithms, such as DAGAN, the LR images used for training are real acquisitions rather than smoothed, downsampled versions of the HR images.

Results

The proposed method is validated qualitatively and quantitatively for an acceleration factor of 4. Favourable comparison is demonstrated against the state-of-the-art DeblurGAN and DAGAN algorithms in terms of PSNR and SSIM scores. The result was further confirmed by an image quality rating experiment performed by four senior neuroradiologists.

Conclusions

The proposed method may become a valuable tool for scan time reduction in brain MRI. In continuation of this research, the validation should be extended to larger datasets acquired for different imaging protocols, and considering several MRI machines produced by different vendors.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literature
1.
go back to reference Armanious K, Jiang C, Fischer M, Küstner T, Hepp T, Nikolaou K, Gatidis S, Yang B (2020) Medgan: medical image translation using GANs. Comput Med Imaging Gr 79:101684CrossRef Armanious K, Jiang C, Fischer M, Küstner T, Hepp T, Nikolaou K, Gatidis S, Yang B (2020) Medgan: medical image translation using GANs. Comput Med Imaging Gr 79:101684CrossRef
2.
go back to reference Blau Y, Mechrez R, Timofte R, Michaeli T, Zelnik-Manor L (2019)The 2018 PIRM challenge on perceptual image super-resolution. In: Proceedings of the ECCV 2018 Workshops, LNCS 11133, Springer Blau Y, Mechrez R, Timofte R, Michaeli T, Zelnik-Manor L (2019)The 2018 PIRM challenge on perceptual image super-resolution. In: Proceedings of the ECCV 2018 Workshops, LNCS 11133, Springer
3.
go back to reference Chaudhari AS, Fang Z, Kogan F, Wood J, Stevens KJ, Gibbons EK, Lee JH, Gold GE, Hargreaves BA (2018) Super-resolution musculoskeletal MRI using deep learning. Magn Reson Med: An Off J Int Soc Magn Reson Med 80(5):2139–2154 Chaudhari AS, Fang Z, Kogan F, Wood J, Stevens KJ, Gibbons EK, Lee JH, Gold GE, Hargreaves BA (2018) Super-resolution musculoskeletal MRI using deep learning. Magn Reson Med: An Off J Int Soc Magn Reson Med 80(5):2139–2154
4.
go back to reference Cohen JP, Luck M, Honari S (2018) Distribution matching losses can hallucinate features in medical image translation. In: Proceedings of the MICCAI 2018, LNCS 11070, pp. 529–536, Springer Cohen JP, Luck M, Honari S (2018) Distribution matching losses can hallucinate features in medical image translation. In: Proceedings of the MICCAI 2018, LNCS 11070, pp. 529–536, Springer
5.
go back to reference Dar SUH, Yurt M, Shahdloo M, Ildız ME, Çukur T (2018) Synergistic reconstruction and synthesis via generative adversarial networks for accelerated multi-contrast MRI. arXiv preprint arXiv:1805.10704 Dar SUH, Yurt M, Shahdloo M, Ildız ME, Çukur T (2018) Synergistic reconstruction and synthesis via generative adversarial networks for accelerated multi-contrast MRI. arXiv preprint arXiv:​1805.​10704
6.
go back to reference Edelstein WA, Hutchison JM, Johnson G, Redpath T (1980) Spin warp NMR imaging and applications to human whole-body imaging. Phys Med Biol 25(4):751CrossRef Edelstein WA, Hutchison JM, Johnson G, Redpath T (1980) Spin warp NMR imaging and applications to human whole-body imaging. Phys Med Biol 25(4):751CrossRef
7.
go back to reference Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, Wang J, Kiefer B, Haase A (2002) Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med: An Off J Int Soc Magn Reson Med 47(6):1202–1210CrossRef Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, Wang J, Kiefer B, Haase A (2002) Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med: An Off J Int Soc Magn Reson Med 47(6):1202–1210CrossRef
8.
go back to reference He K, Zhang X, Ren S, Sun J (2016) Deep residual learning for image recognition. In: Proceedings of the IEEE CVPR, pp. 770–778 He K, Zhang X, Ren S, Sun J (2016) Deep residual learning for image recognition. In: Proceedings of the IEEE CVPR, pp. 770–778
9.
go back to reference Hollingsworth KG (2015) Reducing acquisition time in clinical MRI by data undersampling and compressed sensing reconstruction. Phys Med Biol 60(21):R297CrossRef Hollingsworth KG (2015) Reducing acquisition time in clinical MRI by data undersampling and compressed sensing reconstruction. Phys Med Biol 60(21):R297CrossRef
10.
go back to reference Jaspan ON, Fleysher R, Lipton ML (2015) Compressed sensing MRI: a review of the clinical literature. The Br J Radiol 88(1056):20150487CrossRef Jaspan ON, Fleysher R, Lipton ML (2015) Compressed sensing MRI: a review of the clinical literature. The Br J Radiol 88(1056):20150487CrossRef
11.
go back to reference Johnson J, Alahi A, Fei-Fei L (2016) Perceptual losses for real-time style transfer and super-resolution. In: Proceedings of the ECCV 2016, LNCS 9906. pp. 694–711. Springer Johnson J, Alahi A, Fei-Fei L (2016) Perceptual losses for real-time style transfer and super-resolution. In: Proceedings of the ECCV 2016, LNCS 9906. pp. 694–711. Springer
12.
go back to reference Klein S, Staring M, Murphy K, Viergever MA, Pluim JP (2009) Elastix: a toolbox for intensity-based medical image registration. IEEE Trans Med Imaging 29(1):196–205CrossRef Klein S, Staring M, Murphy K, Viergever MA, Pluim JP (2009) Elastix: a toolbox for intensity-based medical image registration. IEEE Trans Med Imaging 29(1):196–205CrossRef
13.
go back to reference Knoll F, Murrell T, Sriram A, Yakubova N, Zbontar J, Rabbat M, Defazio A, Muckley MJ, Sodickson DK, Zitnick CL (2020) Advancing machine learning for MR image reconstruction with an open competition: overview of the 2019 fastMRI challenge. Magn Reson Med 84(6):3054–3070CrossRef Knoll F, Murrell T, Sriram A, Yakubova N, Zbontar J, Rabbat M, Defazio A, Muckley MJ, Sodickson DK, Zitnick CL (2020) Advancing machine learning for MR image reconstruction with an open competition: overview of the 2019 fastMRI challenge. Magn Reson Med 84(6):3054–3070CrossRef
14.
go back to reference Kupyn O, Budzan V, Mykhailych M, Mishkin D, Matas J (2018) DeblurGAN: Blind motion deblurring using conditional adversarial networks. In: Proceedings of the IEEE CVPR, pp. 8183–8192 Kupyn O, Budzan V, Mykhailych M, Mishkin D, Matas J (2018) DeblurGAN: Blind motion deblurring using conditional adversarial networks. In: Proceedings of the IEEE CVPR, pp. 8183–8192
15.
go back to reference Ledig C, Theis L, Huszár F, Caballero J, Cunningham A, Acosta A, Aitken A, Tejani A, Totz J, Wang Z (2017) Photo-realistic single image super-resolution using a generative adversarial network. In: Proceedings of the IEEE CVPR, pp. 4681–4690 Ledig C, Theis L, Huszár F, Caballero J, Cunningham A, Acosta A, Aitken A, Tejani A, Totz J, Wang Z (2017) Photo-realistic single image super-resolution using a generative adversarial network. In: Proceedings of the IEEE CVPR, pp. 4681–4690
16.
go back to reference Lustig M, Donoho DL, Santos JM, Pauly JM (2008) Compressed sensing MRI. IEEE Signal Process Mag 25(2):72–82CrossRef Lustig M, Donoho DL, Santos JM, Pauly JM (2008) Compressed sensing MRI. IEEE Signal Process Mag 25(2):72–82CrossRef
19.
go back to reference Mardani M, Gong E, Cheng JY, Vasanawala SS, Zaharchuk G, Xing L, Pauly JM (2018) Deep generative adversarial neural networks for compressive sensing MRI. IEEE Trans Med Imaging 38(1):167–179CrossRef Mardani M, Gong E, Cheng JY, Vasanawala SS, Zaharchuk G, Xing L, Pauly JM (2018) Deep generative adversarial neural networks for compressive sensing MRI. IEEE Trans Med Imaging 38(1):167–179CrossRef
20.
go back to reference Nah S, Hyun Kim T, Mu Lee K (2017) Deep multi-scale convolutional neural network for dynamic scene deblurring. In: Proceedings of the IEEE CVPR, pp. 3883–3891 Nah S, Hyun Kim T, Mu Lee K (2017) Deep multi-scale convolutional neural network for dynamic scene deblurring. In: Proceedings of the IEEE CVPR, pp. 3883–3891
21.
go back to reference Pan J, Sun D, Pfister H, Yang MH (2016) Blind image deblurring using dark channel prior. In: Proceedings of the IEEE CVPR, pp. 1628–1636 Pan J, Sun D, Pfister H, Yang MH (2016) Blind image deblurring using dark channel prior. In: Proceedings of the IEEE CVPR, pp. 1628–1636
22.
go back to reference Pham CH, Tor-Díez C, Meunier H, Bednarek N, Fablet R, Passat N, Rousseau F (2019) Multiscale brain MRI super-resolution using deep 3D convolutional networks. Comput Med Imaging Gr 77:101647CrossRef Pham CH, Tor-Díez C, Meunier H, Bednarek N, Fablet R, Passat N, Rousseau F (2019) Multiscale brain MRI super-resolution using deep 3D convolutional networks. Comput Med Imaging Gr 77:101647CrossRef
23.
go back to reference Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P (1999) Sense: sensitivity encoding for fast MRI. Magn Reson Med 42(5):952–962CrossRef Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P (1999) Sense: sensitivity encoding for fast MRI. Magn Reson Med 42(5):952–962CrossRef
24.
go back to reference Simonyan K, Zisserman A. Very deep convolutional networks for large-scale image recognition. The 3rd International Conference on Learning Representations (ICLR2015) Simonyan K, Zisserman A. Very deep convolutional networks for large-scale image recognition. The 3rd International Conference on Learning Representations (ICLR2015)
25.
go back to reference Tao X, Gao H, Shen X, Wang J, Jia J (2018) Scale-recurrent network for deep image deblurring. In: Proceedings of the IEEE CVPR, pp. 8174–8182 Tao X, Gao H, Shen X, Wang J, Jia J (2018) Scale-recurrent network for deep image deblurring. In: Proceedings of the IEEE CVPR, pp. 8174–8182
26.
go back to reference Wang Z, Bovik AC, Sheikh HR, Simoncelli EP (2004) Image quality assessment: from error visibility to structural similarity. IEEE Trans Image Process 13(4):600–612CrossRef Wang Z, Bovik AC, Sheikh HR, Simoncelli EP (2004) Image quality assessment: from error visibility to structural similarity. IEEE Trans Image Process 13(4):600–612CrossRef
27.
go back to reference Yang G, Yu S, Dong H, Slabaugh G, Dragotti PL, Ye X, Liu F, Arridge S, Keegan J, Guo Y (2017) Dagan: deep de-aliasing generative adversarial networks for fast compressed sensing MRI reconstruction. IEEE Trans Med Imaging 37(6):1310–1321CrossRef Yang G, Yu S, Dong H, Slabaugh G, Dragotti PL, Ye X, Liu F, Arridge S, Keegan J, Guo Y (2017) Dagan: deep de-aliasing generative adversarial networks for fast compressed sensing MRI reconstruction. IEEE Trans Med Imaging 37(6):1310–1321CrossRef
28.
go back to reference Yi X, Walia E, Babyn P (2019) Generative adversarial network in medical imaging: a review. Med Image Anal 58:101552 Yi X, Walia E, Babyn P (2019) Generative adversarial network in medical imaging: a review. Med Image Anal 58:101552
29.
go back to reference Zbontar J, Knoll F, Sriram A, Muckley MJ, Bruno M, Defazio A, Parente M, Geras KJ, Katsnelson J, Chandarana H, Zhang Z, Drozdzal M, Romero A, Rabbat M, Vincent P, Pinkerton J, Wang D, Yakubova N, Owens E, Zitnick CL, Recht MP, Sodickson DK, Lui YW (2018) fastMRI: An open dataset and benchmarks for accelerated MRI. arXiv preprint arXiv:1811.08839 Zbontar J, Knoll F, Sriram A, Muckley MJ, Bruno M, Defazio A, Parente M, Geras KJ, Katsnelson J, Chandarana H, Zhang Z, Drozdzal M, Romero A, Rabbat M, Vincent P, Pinkerton J, Wang D, Yakubova N, Owens E, Zitnick CL, Recht MP, Sodickson DK, Lui YW (2018) fastMRI: An open dataset and benchmarks for accelerated MRI. arXiv preprint arXiv:​1811.​08839
Metadata
Title
Anisotropic neural deblurring for MRI acceleration
Authors
Maya Mayberg
Michael Green
Mark Vasserman
Dominique Raichman
Eugenia Belenky
Michael Wolf
Shai Shrot
Nahum Kiryati
Eli Konen
Arnaldo Mayer
Publication date
03-12-2021
Publisher
Springer International Publishing
Published in
International Journal of Computer Assisted Radiology and Surgery / Issue 2/2022
Print ISSN: 1861-6410
Electronic ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-021-02535-6

Other articles of this Issue 2/2022

International Journal of Computer Assisted Radiology and Surgery 2/2022 Go to the issue

Premium Partner