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Amplification and Sequence Analysis of TPI Gene, a Structural Gene of Operon from Lactobacillus delbrueckii Read chapter Read first chapter

2015 | OriginalPaper | Chapter

4. Anti-cancer Activity of Selected Seaweeds Against HeLa, K-562 and MDA-MB Cell Lines

Authors : Ilahi Shaik, A. Shameem, P. Sasi Bhushana Rao

Published in: Biotechnology and Bioforensics

Publisher: Springer Singapore

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Abstract

Anticancer activity of marine macro algae (seaweeds) Sargassum wightii, Ulva fasciata and Gracillaria corticata against HeLa, K-562 and MDA-MB cell lines was studied. During the present investigation crude extracts of seaweeds were prepared using soxhlet apparatus. Hexane, Butanol and Methanol were used as solvents. Crude extracts were dissolved in DMSO. In vitro anticancer activity of seaweeds at various concentrations (12.5–200 μg/ml) was studied against the chosen cell lines using MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, a yellow tetrazole). Butanolic extract of Gracillaria corticata (200 µg/ml) has shown greater anticancer activity than hexane and methanolic extracts of G. corticata and butanol, hexane and methanolic extracts of Sargassum wightii and Ulva fasciata.

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Metadata
Title
Anti-cancer Activity of Selected Seaweeds Against HeLa, K-562 and MDA-MB Cell Lines
Authors
Ilahi Shaik
A. Shameem
P. Sasi Bhushana Rao
Copyright Year
2015
Publisher
Springer Singapore
Book
Biotechnology and Bioforensics

Print ISBN: 978-981-287-049-0

Electronic ISBN: 978-981-287-050-6

Copyright Year: 2015

DOI
https://doi.org/10.1007/978-981-287-050-6_4

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