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Birth of Mechanical Engineering and a Glimpse into the Future Trends Read chapter Read first chapter

2021 | OriginalPaper | Chapter

Current Status of the Development of Blood-Based Point-of-Care Microdevices

Authors : Vijai Laxmi, Siddhartha Tripathi, Amit Agrawal

Published in: Mechanical Sciences

Publisher: Springer Singapore

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Abstract

Blood is one of the most common human tissues required to assess the human health condition. In a conventional setup, disease diagnosis includes consultation with a health practitioner, blood analysis, and follow up. Overall, the diagnosis process is time consuming and delays the timely treatment of the patients. Point-of-care technology (POCT) is rapidly progressing toward providing innovative and efficient solutions for diagnosing. Point-of-care (POC) devices are portable, provide on-site testing of the blood within few minutes, and utilize small volume of blood. Lab-on-chip microfluidic devices play a key role in the progress of POCT. Several lab-on-chip (LOC) microdevices have been reported in literature for the successful detection of various diseases using blood as a sample fluid. Here, we review blood-based lab-on-chip microfluidics devices dedicated to the point-of-care technology. Our review focuses on the technologies and designs of various dedicated microdevices toward disease diagnostics in reference with blood components such as plasma, red blood cells, white blood cells, platelets, and circulating tumor cells. The review should therefore serve as a useful reference for the development of future blood-based POC devices.

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Metadata
Title
Current Status of the Development of Blood-Based Point-of-Care Microdevices
Authors
Vijai Laxmi
Siddhartha Tripathi
Amit Agrawal
Copyright Year
2021
Publisher
Springer Singapore
Book
Mechanical Sciences

Print ISBN: 978-981-15-5711-8

Electronic ISBN: 978-981-15-5712-5

Copyright Year: 2021

DOI
https://doi.org/10.1007/978-981-15-5712-5_8

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