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Published in: Cellulose 3/2014

01-06-2014 | Original Paper

In situ fabrication of a microporous bacterial cellulose/potato starch composite scaffold with enhanced cell compatibility

Authors: Jingxuan Yang, Xiangguo Lv, Shiyan Chen, Zhe Li, Chao Feng, Huaping Wang, Yuemin Xu

Published in: Cellulose | Issue 3/2014

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Abstract

Microporous bacterial cellulose/potato starch (BC/PS) composites composed of a compact upper surface and transparent lower surface were fabricated by an in situ method by adding PS into the culture medium. The special structure formation mechanism was explored. Compared with original BC, a locally oriented surface morphology was observed when the concentration of PS in the culture media was above 1.0 %. Many more free spaces were made after modification with pore size reaching 40 μm. An obvious cell ingrowth tendency was observed on the porous surface of BC/PS composites as the starch content increased, while most of muscle-derived cells could only proliferate on the surface of original BCs. In vivo implantation showed the transparent fibrous lower side of BC/PS composites was much easier for neovascularization, and no obvious sign of inflammation was observed.

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Metadata
Title
In situ fabrication of a microporous bacterial cellulose/potato starch composite scaffold with enhanced cell compatibility
Authors
Jingxuan Yang
Xiangguo Lv
Shiyan Chen
Zhe Li
Chao Feng
Huaping Wang
Yuemin Xu
Publication date
01-06-2014
Publisher
Springer Netherlands
Published in
Cellulose / Issue 3/2014
Print ISSN: 0969-0239
Electronic ISSN: 1572-882X
DOI
https://doi.org/10.1007/s10570-014-0220-8

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