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Polymer Bulletin
Published in: Polymer Bulletin 12/2013

01-12-2013 | Original Paper

In vitro degradation assessment of optically active poly(urethane-imide)s based on α-amino acids

Authors: Shadpour Mallakpour, Mohammad R. Sabzalian

Published in: Polymer Bulletin | Issue 12/2013

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Abstract

The aim of this work is to obtain optically and biologically active poly(urethane-imide)s (PUIs) using N,N’-(pyromellitoyl)-bis-l-tyrosine dimethyl ester (5) as a chiral and biologically active diphenolic monomer. Step-growth polymerization of diol 5 with various aliphatic and aromatic diisocyanates was carried out by gradual heating technique. The resulting PUIs were characterized with FT-IR, and two of them by 1H-NMR spectroscopy and elemental analysis. Thermogravimetric analysis and differential scanning calorimetry were used to determine the thermal properties of the two representative PUIs. The morphology of polymer was studied by X-ray diffraction analysis. Furthermore, in vitro toxicity and biodegradability behaviors of the obtained PUIs were studied in culture media and soil burial degradation which reveals that the synthesized polymers are biologically active and biodegradable in natural environment.
previous article A comparative study on antibacterial activities of chitosan based products and their combinations with gentamicin against S. epidermidis and E. coli
next article Palm fibre-reinforced hybrid composites of poly(butylene succinate): characterisation and assessment of mechanical and thermal properties

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Metadata
Title
In vitro degradation assessment of optically active poly(urethane-imide)s based on α-amino acids
Authors
Shadpour Mallakpour
Mohammad R. Sabzalian
Publication date
01-12-2013
Publisher
Springer Berlin Heidelberg
Published in
Polymer Bulletin / Issue 12/2013
Print ISSN: 0170-0839
Electronic ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-013-1031-z

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