Top

Journal of Nanoparticle Research

Published in:

01-11-2014 | Research Paper

Ligands influence a carbon nanotube penetration through a lipid bilayer

Authors: Fei Liu, Dan Wu, Ken Chen

Published in: Journal of Nanoparticle Research | Issue 11/2014

Activate our intelligent search to find suitable subject content or patents.

search-config

AI-assisted search

Off

Abstract

The interactions between nanomaterials and biological membranes are important for the safe use of nanomaterials. We explore the nano–bio interface by studying the penetration of a carbon nanotube (CNT) coated with ligands through a lipid bilayer. With a dissipative particle dynamics model, the mechanism of ligands influencing nano–bio interaction is analyzed. The CNTs with different ligands are tested. The simulation shows that the increase of the total number of ligand particles decreases the capability of a CNT penetrating through a membrane. For the CNTs with the same number of ligand particles, the arrangements of their ligands determine their behaviors. The asymmetrical pattern generates an upside down phenomenon, which requires more energy to get through the membrane; the uniform distribution penetrates through a membrane with less difficulty. Decreasing the stiffness, the length of ligands or preferring hydrophobic ligands increases the penetration capability of CNTs.

previous article Ultrathin BiOBr nanocrystals with dominant {001} facets and their high photocatalytic activity

next article Enhanced polymer light-emitting diode property using fluorescent conducting polymer-reduced graphene oxide nanocomposite as active emissive layer

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

inform now

Almquist BD, Verma P, Cai W, Melosh NA (2011) Nanoscale patterning controls inorganic–membrane interface structure. Nanoscale 3(2):391–400CrossRef

Bahadur K, Thapa B, Bhattarai N (2014) Gold nanoparticle-based gene delivery: promises and challenges. Nanotechnol Rev 3(3):269–280CrossRef

Chen X, Kis A, Zettl A, Bertozzi CR (2007) A cell nanoinjector based on carbon nanotubes. Proc Natl Acad Sci 104(20):8218–8222CrossRef

Cho ES, Kim J, Tejerina B, Hermans TM, Jiang H, Nakanishi H, Yu M, Patashinski AZ, Glotzer SC, Stellacci F (2012) Ultrasensitive detection of toxic cations through changes in the tunnelling current across films of striped nanoparticles. Nat Mater 11(11):978–985CrossRef

Donkor DA, Tang XS (2014) Tube length and cell type-dependent cellular responses to ultra-short single-walled carbon nanotube. Biomaterials 35(9):3121–3131CrossRef

Espanol P, Warren P (1995) Statistical mechanics of dissipative particle dynamics. EPL (Europhys Lett) 30:191CrossRef

Esser B, Schnorr JM, Swager TM (2012) Selective detection of ethylene gas using carbon nanotube-based devices: utility in determination of fruit ripeness. Angew Chem Int Ed 51(23):5752–5756CrossRef

Fabbro C, Ros TD, Prato M (2013) Carbon nanotube derivatives as anticancer drug delivery systems. In: Chiara Fabbro, Tatiana Da Ros, Maurizio Prato (eds) Organic nanomaterials: synthesis, characterization, and device applications. Wiley, New York, pp 469–486

Gagner JE, Shrivastava S, Qian X, Dordick JS, Siegel RW (2012) Engineering nanomaterials for biomedical applications requires understanding the nano–bio interface: a perspective. J Phys Chem Lett 3(21):3149–3158CrossRef

Ganzenmüller G, Hiermaier S, Steinhauser M (2011) Shock-wave induced damage in lipid bilayers: a dissipative particle dynamics simulation study. Soft Matter 7(9):4307–4317CrossRef

Gao L, Shillcock J, Lipowsky R (2007) Improved dissipative particle dynamics simulations of lipid bilayers. J Chem Phys 126:015101CrossRef

Gkeka P, Sarkisov L, Angelikopoulos P (2013) Homogeneous hydrophobic–hydrophilic surface patterns enhance permeation of nanoparticles through lipid membranes. J Phys Chem Lett 4(11):1907–1912CrossRef

Goetz R, Lipowsky R (1998) Computer simulations of bilayer membranes: self-assembly and interfacial tension. J Chem Phys 108:7397CrossRef

Goicochea AG (2014) Designing biodegradable surfactants and effective biomolecules with dissipative particle dynamics. Experimental and Computational Fluid Mechanics. Springer, Switzerland, pp 433–447

Groot RD, Warren PB (1997) Dissipative particle dynamics: bridging the gap between atomistic and mesoscopic simulation. J Chem Phys 107(11):4423CrossRef

Hwang SR, Ku SH, Joo MK, Kim SH, Kwon IC (2014) Theranostic nanomaterials for image-guided gene therapy. MRS Bull 39(01):44–50CrossRef

Iijima S (1991) Helical microtubules of graphitic carbon. Nature 354(6348):56–58CrossRef

Illya G, Lipowsky R, Shillcock J (2005) Effect of chain length and asymmetry on material properties of bilayer membranes. J Chem Phys 122:244901CrossRef

Jackson AM, Myerson JW, Stellacci F (2004) Spontaneous assembly of subnanometre-ordered domains in the ligand shell of monolayer-protected nanoparticles. Nat Mater 3(5):330–336CrossRef

Jang SG, Audus DJ, Klinger D, Krogstad DV, Kim BJ, Cameron A, Kim S-W, Delaney KT, Hur S-M, Killops KL (2013) Striped, ellipsoidal particles by controlled assembly of diblock copolymers. J Am Chem Soc 135(17):6649–6657CrossRef

Jusufi A, DeVane RH, Shinoda W, Klein ML (2011) Nanoscale carbon particles and the stability of lipid bilayers. Soft Matter 7(3):1139–1146CrossRef

Kraszewski S, Picaud F, Elhechmi I, Gharbi T, Ramseyer C (2012) How long a functionalized carbon nanotube can passively penetrate a lipid membrane. Carbon 50(14):5301–5308CrossRef

Liu Z, Tabakman SM, Chen Z, Dai H (2009) Preparation of carbon nanotube bioconjugates for biomedical applications. Nat Protoc 4(9):1372–1381CrossRef

Liu X, Yu M, Kim H, Mameli M, Stellacci F (2012) Determination of monolayer-protected gold nanoparticle ligand–shell morphology using NMR. Nat commun 3:1182CrossRef

Liu F, Wu D, Kamm RD, Chen K (2013a) Analysis of nanoprobe penetration through a lipid bilayer. Biochimica et Biophysica Acta (BBA)-Biomembr 1828(8):1667–1673CrossRef

Liu L, Yang C, Zhao K, Li J, Wu H-C (2013b) Ultrashort single-walled carbon nanotubes in a lipid bilayer as a new nanopore sensor. Nat commun 4:2989

Mei L, Zhang Z, Zhao L, Huang L, Yang X-L, Tang J, Feng S-S (2013) Pharmaceutical nanotechnology for oral delivery of anticancer drugs. Adv Drug Deliv Rev 65(6):880–890CrossRef

Moglianetti M, Ong QK, Reguera J, Harkness KM, Mameli M, Radulescu A, Kohlbrecher J, Jud C, Svergun DI, Stellacci F (2014) Scanning tunneling microscopy and small angle neutron scattering study of mixed monolayer protected gold nanoparticles in organic solvents. Chem Sci 5(3):1232–1240CrossRef

Moser ML, Tian X, Pekker A, Sarkar S, Bekyarova E, Itkis ME, Haddon RC (2014) Hexahapto-lanthanide interconnects between the conjugated surfaces of single-walled carbon nanotubes. Dalton Trans 43(20):7379–7382CrossRef

Münzer AM, Seo W, Morgan GJ, Michael ZP, Zhao Y, Melzer K, Scarpa G, Star A (2014) Sensing reversible protein–ligand interactions with single-walled carbon nanotube field-effect transistors. J Phys Chem C 118(31):17193–17199CrossRef

Nel AE, Mädler L, Velegol D, Xia T, Hoek EM, Somasundaran P, Klaessig F, Castranova V, Thompson M (2009) Understanding biophysicochemical interactions at the nano–bio interface. Nat Mater 8(7):543–557CrossRef

Obataya I, Nakamura C, Han S, Nakamura N, Miyake J (2005) Nanoscale operation of a living cell using an atomic force microscope with a nanoneedle. Nano Lett 5(1):27–30CrossRef

Ormsby RW, McNally T, Mitchell CA, Musumeci A, Schiller T, Halley P, Gahan L, Martin D, Smith SV, Dunne NJ (2014) Chemical modification of multiwalled carbon nanotube with a bifunctional caged ligand for radioactive labelling. Acta Mater 64:54–61CrossRef

Ortiz V, Nielsen SO, Discher DE, Klein ML, Lipowsky R, Shillcock J (2005) Dissipative particle dynamics simulations of polymersomes. J Phys Chem B 109(37):17708–17714CrossRef

Park K (2013) Facing the truth about nanotechnology in drug delivery. ACS Nano 7(9):7442–7447CrossRef

Peng Z, Pivkin IV, Li X, Karniadakis GE, Dao M (2014) Two-component dissipative particle dynamics model of red blood cells. Biophys J 106(2):573a

Pogodin S, Baulin VA (2010) Can a carbon nanotube pierce through a phospholipid bilayer? ACS Nano 4(9):5293–5300CrossRef

Sapna J, Shree RS, Shreekumar P (2012) Toxicity issues related to biomedical applications of carbon nanotubes. J Nanomed Nanotechnol 3:140

Sarukhanyan E, De Nicola A, Roccatano D, Kawakatsu T, Milano G (2014) Spontaneous insertion of carbon nanotube bundles inside biomembranes: a hybrid particle-field coarse-grained molecular dynamics study. Chem Phys Lett 595:156–166CrossRef

Tan SJ, Jana NR, Gao S, Patra PK, Ying JY (2010) Surface-ligand-dependent cellular interaction, subcellular localization, and cytotoxicity of polymer-coated quantum dots. Chem Mater 22(7):2239–2247CrossRef

Van Lehn RC, Alexander-Katz A (2011) Penetration of lipid bilayers by nanoparticles with environmentally-responsive surfaces: simulations and theory. Soft Matter 7(24):11392–11404CrossRef

Verma A, Stellacci F (2010) Effect of surface properties on nanoparticle–cell interactions. Small 6(1):12–21CrossRef

Verma A, Uzun O, Hu Y, Hu Y, Han H-S, Watson N, Chen S, Irvine DJ, Stellacci F (2008) Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. Nat Mater 7(7):588–595CrossRef

Yang K, Ma Y-Q (2010) Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer. Nat Nanotechnol 5(8):579–583CrossRef

Yang W, Thordarson P, Gooding JJ, Ringer SP, Braet F (2007) Carbon nanotubes for biological and biomedical applications. Nanotechnology 18(41):412001CrossRef

Young AN, Kairdolf BA (2013) Nanotechnology in molecular diagnostics. In: Cheng L, Zhang DY (eds) Molecular genetic pathology, 2nd edn. Springer, New York, pp 383–398

Title: Ligands influence a carbon nanotube penetration through a lipid bilayer
Authors: Fei Liu
Dan Wu
Ken Chen
Publication date: 01-11-2014
Publisher: Springer Netherlands
Published in: Journal of Nanoparticle Research / Issue 11/2014
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-014-2692-8

Springer Professional

Abstract

Please log in to get access to your license.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Springer Professional "Technik"

Other articles of this Issue 11/2014

UV radiation: a promising tool in the synthesis of multicomponent nano-oxides

Experimental study of fractal clusters formation from nanoparticles synthesized by atmospheric pressure plasma-enhanced chemical vapor deposition

ATMP-stabilized iron nanoparticles: chelator-controlled nanoparticle synthesis

Direct electrochemistry of GOD on nitrogen-doped porous carbon and its biosensing

Gold nanocage coupled single crystal TiO2 nanostructures for near-infrared water photolysis

Cerium oxide nanoparticles protect primary mouse bone marrow stromal cells from apoptosis induced by oxidative stress

Premium Partners