Skip to main content
Top

2020 | OriginalPaper | Chapter

Nanomedicines in Cancer Therapy

Authors : Enas Abu-Qudais, Balakumar Chandrasekaran, Sara Samarneh, Ghadir Kassab

Published in: Integrative Nanomedicine for New Therapies

Publisher: Springer International Publishing

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

Cancer is one of the most controversial diseases known for humanity and emerged as a global health problem all the time. The drug discovery scientists and clinicians have attempted to cure cancer since centuries. Conventional cancer treatments such as radiotherapy and chemotherapy have many limitations including low specificity, lack of stability, rapid drug clearance, biodegradation and limited targeting besides number of side effects associated with these treatments on the actual patients. Nanomedicine has evolved over the past few years and became a breakthrough technology for the diagnosis and the treatment of several cancer types. Specifically, the drug is being carried out through carriers called nanoparticles in which the properties of these carriers are very important for the successful treatment of deadly diseases like cancer. In this chapter, we describe the application of nanotechnology and nanomedicines in the diagnosis and treatment of cancer. Further, we discuss the targeted-nanodrug delivery to cancer cells in a broad context. Moreover, we provide a glimpse on marketed nanomedicines available for the management of cancer.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literature
go back to reference Gianni, L., Pienkowski, T., Im, Y.-H., et al. (2016). 5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): A multicentre, open-label, phase 2 randomised trial. The lancet Oncology, 17, 791–800. https://doi.org/10.1016/S1470-2045(16)00163-7.CrossRef Gianni, L., Pienkowski, T., Im, Y.-H., et al. (2016). 5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): A multicentre, open-label, phase 2 randomised trial. The lancet Oncology, 17, 791–800. https://​doi.​org/​10.​1016/​S1470-2045(16)00163-7.CrossRef
go back to reference Pal, S. L., Jana, U., Manna, P. K., et al. (2011). Nanoparticle: An overview of preparation and characterization. Journal of Applied Pharmaceutical Science, 1, 228–234. Pal, S. L., Jana, U., Manna, P. K., et al. (2011). Nanoparticle: An overview of preparation and characterization. Journal of Applied Pharmaceutical Science, 1, 228–234.
go back to reference Sandanaraj, B. S., Gremlich, H.-U., Kneuer, R., et al. (2010). Fluorescent nanoprobes as a biomarker for increased vascular permeability: Implications in diagnosis and treatment of cancer and inflammation. Bioconjugate Chemistry, 21, 93–101. https://doi.org/10.1021/bc900311h.CrossRef Sandanaraj, B. S., Gremlich, H.-U., Kneuer, R., et al. (2010). Fluorescent nanoprobes as a biomarker for increased vascular permeability: Implications in diagnosis and treatment of cancer and inflammation. Bioconjugate Chemistry, 21, 93–101. https://​doi.​org/​10.​1021/​bc900311h.CrossRef
go back to reference Singh, P. K., Doley, J., Kumar, G. R., et al. (2012). Oncolytic viruses & their specific targeting to tumour cells. Indian Journal of Medical Research, 136, 571–584. Singh, P. K., Doley, J., Kumar, G. R., et al. (2012). Oncolytic viruses & their specific targeting to tumour cells. Indian Journal of Medical Research, 136, 571–584.
go back to reference Surendiran, A., Sandhiya, S., Pradhan, S. C., & Adithan, C. (2009). Novel applications of nanotechnology in medicine. Indian Journal of Medical Research, 130, 689–701. Surendiran, A., Sandhiya, S., Pradhan, S. C., & Adithan, C. (2009). Novel applications of nanotechnology in medicine. Indian Journal of Medical Research, 130, 689–701.
Metadata
Title
Nanomedicines in Cancer Therapy
Authors
Enas Abu-Qudais
Balakumar Chandrasekaran
Sara Samarneh
Ghadir Kassab
Copyright Year
2020
DOI
https://doi.org/10.1007/978-3-030-36260-7_12

Premium Partners