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Neural Computing and Applications
Published in: Neural Computing and Applications 7-8/2014

01-12-2014 | Original Article

Nonlinear features of heart rate variability in paranoid schizophrenic

Authors: Mohamed Abdelkader Aboamer, Ahmad Taher Azar, Abdallah S. A. Mohamed, Karl-Jürgen Bär, Sandy Berger, Khaled Wahba

Published in: Neural Computing and Applications | Issue 7-8/2014

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Abstract

Cardiovascular mortality is significantly increased in patients suffering from schizophrenia. However, psychotic symptoms are quantified by means of the scale for the assessment of positive and negative symptoms, but many investigations try to introduce new etiology for psychiatric disorders based on combination of biological, psychological and social causes. Classification between healthy and paranoid cases has been achieved by time, frequency, Hilbert–Huang (HH) and a combination between those features as a hybrid features. Those features extracted from the Hilbert–Huang transform for each intrinsic mode function (IMF) of the detrended time series for each healthy case and paranoid case. Short-term ECG recordings of 20 unmedicated patients suffering from acute paranoid schizophrenia and those obtained from healthy matched peers have been utilized in this investigation. Frequency features: very low frequency (VLF), low frequency (LF), high frequency (HF) and HF/LF (ratio) produced promising success rate equal to 97.82 % in training and 97.77 % success rate in validation by means of IMF1 and ninefolds. Time–frequency features [LF, HF and ratio, mean, maximum (max), minimum (min) and standard deviation (SD)] provided 100 % success in both training and validation trials by means of ninefolds for IMF1 and IMF2. By utilizing IMF1 and ninefolds, frequency and Hilbert–Hang features [LF, HF, ratio, mean value of envelope (\(\bar{a}\))] produced 96.87 and 95.5 % for training and validation, respectively. By analyzing the first IMF and using ninefolds, time and Hilbert–Hang features [mean, max, min, SD, median, first quartile (Q1), third quartile (Q3), kurtosis, skewness, Shannon entropy, approximate entropy and energy, (\(\bar{a}\)), level of envelope variation ([\(\dot{a}\)(t)]^2), central frequency \((\bar{W})\) and number of zero signal crossing \((\left| {\bar{W}} \right|)\)] produced a 100 % success rate in training and 90 % success rate in validation. Time, frequency and HH features [energy, VLF, LF, HF, ratio and (\(\bar{a}\))] provided 97.5 % success rate in training and 95.24 % success rate in validation using IMF1 and sixfolds. However, frequency features have produced promising classification success rate, but hybrid features emerged the highest classification success rate than using features in each domain separately.
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Metadata
Title
Nonlinear features of heart rate variability in paranoid schizophrenic
Authors
Mohamed Abdelkader Aboamer
Ahmad Taher Azar
Abdallah S. A. Mohamed
Karl-Jürgen Bär
Sandy Berger
Khaled Wahba
Publication date
01-12-2014
Publisher
Springer London
Published in
Neural Computing and Applications / Issue 7-8/2014
Print ISSN: 0941-0643
Electronic ISSN: 1433-3058
DOI
https://doi.org/10.1007/s00521-014-1621-1

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