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Progress in Additive Manufacturing

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20-08-2022 | Review Article

Polymer/calcium phosphate biocomposites manufactured by selective laser sintering: an overview

Authors: Henrique Schappo, Karine Giry, Gean Salmoria, Chantal Damia, Dachamir Hotza

Published in: Progress in Additive Manufacturing | Issue 2/2023

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Abstract

Additive manufacturing (AM) has driven important advances in implantable devices for tissue regeneration. Selective Laser Sintering (SLS), also known as Powder Bed Fusion (PBF), is a laser-assisted AM method capable of producing tridimensional parts using different types of materials for various applications. In bone tissue engineering, calcium phosphates (Ca–P), such as tricalcium phosphate (TCP) and hydroxyapatite (HA), have been used due to their biocompatibility and regenerative capacity. Likewise, polylactic acid (PLA) and polycaprolactone (PCL) have also been widely used to fabricate implantable devices due to their processability and suitable properties, such as bioabsorption. Combining a polymeric matrix and an inorganic filler into a biocomposite has been a challenge due to the different nature of the biocomposite components. In this overview, information was gathered from the literature on powder blending approaches, raw materials employed, details of processing parameters, as well as biological evaluation of the products. A comprehensive description is given of the procedures involved in SLS of implantable polymer/Ca–P devices. Particular issues were found related to the processing of Ca–P and polymers such as a small sintering window. In addition, powder flowability and homogeneity have a considerable effect on the processability, affecting the mechanical and biological performance. Thus, properly mixing is a key factor to achieve the desired intermediate and final properties. Nevertheless, biocompatibility tests are essential to support the device’s use in tissue engineering applications but frequently were not shown in the reviewed articles.

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Title: Polymer/calcium phosphate biocomposites manufactured by selective laser sintering: an overview
Authors: Henrique Schappo
Karine Giry
Gean Salmoria
Chantal Damia
Dachamir Hotza
Publication date: 20-08-2022
Publisher: Springer International Publishing
Published in: Progress in Additive Manufacturing / Issue 2/2023
Print ISSN: 2363-9512
Electronic ISSN: 2363-9520
DOI: https://doi.org/10.1007/s40964-022-00332-4

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