Top

Published in:

2018 | OriginalPaper | Chapter

2. Acute Neural Stimulation

Author : Andy Kah Ping Tay

Published in: Acute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels

Publisher: Springer International Publishing

Activate our intelligent search to find suitable subject content or patents.

search-config

AI-assisted search

Off

Abstract

In the previous chapter, I discussed the advantages of using nanotechnologies to probe the mechano-biology of the brain. In this chapter, I describe the development of a magnetic microfabricated substrate and magnetic nanoparticle technology to induce calcium influx in neural networks by enhancing the opening probability of mechano-sensitive N-type Ca²⁺ channels.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

inform now

previous chapter Micro- and Nanotechnologies to Probe Brain Mechanobiology

next chapter Chronic Neural Stimulation

West, A.E., Chen, W.G., Dalva, M.B., Dolmetsch, R.E., Kornhauser, J.M., Shaywitz, A.J., Takasu, M.A., Tao, X., Greenberg, M.E.: Calcium regulation of neuronal gene expression. Proc. Natl. Acad. Sci. U. S. A. 98, 11024–11031 (2001)CrossRef

Mattson, M.P., LaFerla, F.M., Chan, S.L., Leissring, M.A., Shepel, P.N., Geiger, J.D.: Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders. Trends Neurosci. 23, 222–229 (2000)CrossRef

Berridge, M.J., Bootman, M.D., Lipp, P.: Calcium--a life and death signal. Nature. 395, 645–648 (1998)CrossRef

Tsai, H.-C., Zhang, F., Adamantidis, A., Stuber, G.D., Bonci, A., de Lecea, L., Deisseroth, K.: Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science. 324, 1080–1084 (2009)CrossRef

Bernstein, J.G., Garrity, P.A., Boyden, E.S.: Optogenetics and thermogenetics: technologies for controlling the activity of targeted cells within intact neural circuits. Curr. Opin. Neurobiol. 22, 61–71 (2012)CrossRef

Banghart, M., Borges, K., Isacoff, E., Trauner, D., Kramer, R.H.: Light-activated ion channels for remote control of neuronal firing. Nat. Neurosci. 7, 1381–1386 (2004)CrossRef

Tyler, W.J., Tufail, Y., Finsterwald, M., Tauchmann, M.L., Olson, E.J., Majestic, C.: Remote excitation of neuronal circuits using low-intensity, low-frequency ultrasound. PLoS One. 3, e3511 (2008)CrossRef

Marino, A., Arai, S., Hou, Y., Sinibaldi, E., Pellegrino, M., Chang, Y.-T., Mazzolai, B., Mattoli, V., Suzuki, M., Ciofani, G.: Piezoelectric nanoparticle-assisted wireless neuronal stimulation. ACS Nano. 9(7), 7678–7689 (2015)CrossRef

Zemelman, B.V., Lee, G.A., Ng, M., Miesenböck, G.: Selective photostimulation of genetically chARGed neurons. Neuron. 33, 15–22 (2002)CrossRef

10.

Boyden, E.S., Zhang, F., Bamberg, E., Nagel, G., Deisseroth, K.: Millisecond-timescale, genetically targeted optical control of neural activity. Nat. Neurosci. 8, 1263–1268 (2005)CrossRef

11.

Sparta, D.R., Stamatakis, A.M., Phillips, J.L., Hovelsø, N., van Zessen, R., Stuber, G.D.: Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits. Nat. Protoc. 7, 12–23 (2012)CrossRef

12.

Wang, N., Butler, J.P., Ingber, D.E.: Mechanotransduction across the cell surface and through the cytoskeleton. Science. 260, 1124–1127 (1993)CrossRef

13.

Hughes, S., McBain, S., Dobson, J., El Haj, A.J.: Selective activation of mechanosensitive ion channels using magnetic particles. J. R. Soc. Interface. 5, 855–863 (2008)CrossRef

14.

Huang, H., Delikanli, S., Zeng, H., Ferkey, D.M., Pralle, A.: Remote control of ion channels and neurons through magnetic-field heating of nanoparticles. Nat. Nanotechnol. 5, 602–606 (2010)CrossRef

15.

Chen, R., Romero, G., Christiansen, M.G., Mohr, A., Anikeeva, P.: Wireless magnetothermal deep brain stimulation. Science. 347, 1477–1480 (2015)CrossRef

16.

Yuste, R.: From the neuron doctrine to neural networks. Nat. Rev. Neurosci. 16, 487–497 (2015)CrossRef

17.

Kisaalita, W.S., Evans, M., Lund, R.B.: Size changes in differentiating neuroblastoma cells. Vitr. Cell. Dev. Biol. - Anim. 33, 734–737 (1997)CrossRef

18.

Clement, G.T., Nomura, H., Adachi, H., Kamakura, T.: The feasibility of non-contact ultrasound for medical imaging. Phys. Med. Biol. 58, 6263–6278 (2013)CrossRef

19.

Steketee, M.B., Moysidis, S.N., Jin, X.-L., Weinstein, J.E., Pita-Thomas, W., Raju, H.B., Iqbal, S., Goldberg, J.L.: Nanoparticle-mediated signaling endosome localization regulates growth cone motility and neurite growth. Proc. Natl. Acad. Sci. 108, 19042–19047 (2011)CrossRef

20.

Kunze, A., Tseng, P., Godzich, C., Murray, C., Caputo, A., Schweizer, F.E., Di Carlo, D.: Engineering cortical neuron polarity with nanomagnets on a chip. ACS Nano. 9(4), 3664–3676 (2015)CrossRef

21.

Tay, A.K., Dhar, M., Pushkarsky, I., Di Carlo, D.: Research highlights: manipulating cells inside and out. Lab Chip. 15, 2533–2537 (2015)CrossRef

22.

Dobson, J.: Remote control of cellular behaviour with magnetic nanoparticles. Nat. Nanotechnol. 3, 139–143 (2008)CrossRef

23.

Jung, S., Bang, M., Kim, B.S., Lee, S., Kotov, N.A., Kim, B., Jeon, D.: Intracellular gold nanoparticles increase neuronal excitability and aggravate seizure activity in the mouse brain. PLoS One. 9, e91360 (2014)CrossRef

24.

Kim, S., Im, W.S., Kang, L., Lee, S.T., Chu, K., Kim, B.I.: The application of magnets directs the orientation of neurite outgrowth in cultured human neuronal cells. J. Neurosci. Methods. 174, 91–96 (2008)CrossRef

25.

Etoc, F., Vicario, C., Lisse, D., Siaugue, J.-M., Piehler, J., Coppey, M., Dahan, M.: Magnetogenetic control of protein gradients inside living cells with high spatial and temporal resolution. Nano Lett. 15(5), 3487–3494 (2015)CrossRef

26.

Walkey, C.D., Olsen, J.B., Song, F., Liu, R., Guo, H., Olsen, D.W.H., Cohen, Y., Emili, A., Chan, W.C.W.: Protein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticles. ACS Nano. 8, 2439–2455 (2014)CrossRef

27.

Lesniak, A., Fenaroli, F., Monopoli, M.P., Åberg, C., Dawson, K.A., Salvati, A.: Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells. ACS Nano. 6, 5845–5857 (2012)CrossRef

28.

He, C., Hu, Y., Yin, L., Tang, C., Yin, C.: Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials. 31, 3657–3666 (2010)CrossRef

29.

Gao, H., Yang, Z., Zhang, S., Cao, S., Shen, S., Pang, Z., Jiang, X.: Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization. Sci. Rep. 3, 2534 (2013)CrossRef

30.

Westenbroek, R.E., Hell, J.W., Warner, C., Dubel, S.J., Snutch, T.P., Catterall, W.A.: Biochemical properties and subcellular distribution of an N-type calcium channel alpha 1 subunit. Neuron. 9, 1099–1115 (1992)CrossRef

31.

Rao, W., Wang, H., Han, J., Zhao, S., Dumbleton, J., Agarwal, P., Zhang, W., Zhao, G., Yu, J., Zynger, D.L., et al.: Chitosan-decorated doxorubicin-encapsulated nanoparticle targets and eliminates tumor reinitiating cancer stem-like cells. ACS Nano. 9, 5725–5740 (2015)CrossRef

32.

Patel, J.C., Witkovsky, P., Avshalumov, M.V., Rice, M.E.: Mobilization of calcium from intracellular stores facilitates somatodendritic dopamine release. J. Neurosci. 29, 6568–6579 (2009)CrossRef

33.

Dworakowska, B., Dołowy, K., Tyson, J.R., Snutch, T.P., Piontkivska, H., Hughes, A.L., Bidaud, I., Mezghrani, A., Swayne, L.A., Monteil, A., et al.: Molecular nature of voltage-gated calcium channels: structure and species comparison. Wiley Interdiscip. Rev. Membr. Transp. Signal. 2, 181–206 (2013)CrossRef

34.

Calabrese, B., Tabarean, I.V., Juranka, P., Morris, C.E.: Mechanosensitivity of N-type calcium channel currents. Biophys. J. 83, 2560–2574 (2002)CrossRef

35.

McCleskey, E.W., Fox, A.P., Feldman, D.H., Cruz, L.J., Olivera, B.M., Tsien, R.W., Yoshikami, D.: Omega-Conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle. Proc. Natl. Acad. Sci. U. S. A. 84, 4327–4331 (1987)CrossRef

36.

Sabass, B., Stone, H.A.: Mechanosensing by tethered membrane channels. Bull. Am. Phys. Soc. 61, 2 (2016)

37.

Coste, B., Mathur, J., Schmidt, M., Earley, T.J., Ranade, S., Petrus, M.J., Dubin, A.E., Patapoutian, A.: Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science. 330, 55–60 (2010)CrossRef

38.

Zhao, Q., Wu, K., Geng, J., Chi, S., Wang, Y., Zhi, P., Zhang, M., Xiao, B.: Ion permeation and mechanotransduction mechanisms of mechanosensitive piezo channels. Neuron. 89, 1248–1263 (2016)CrossRef

39.

Tay, A., Kunze, A., Jun, D., Hoek, E., Di Carlo, D.: The age of cortical neural networks affects their interactions with magnetic nanoparticles. Small. 12(26), 3559–3567 (2016)CrossRef

40.

Chameau, P., Lucas, P., Melliti, K., Bournaud, R., Shimahara, T.: Development of multiple calcium channel types in cultured mouse hippocampal neurons. Neuroscience. 90, 383–388 (1999)CrossRef

41.

Stanley, S.A., Gagner, J.E., Damanpour, S., Yoshida, M., Dordick, J.S., Friedman, J.M.: Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science. 336, 604–608 (2012)CrossRef

42.

Stanley, S.A., Sauer, J., Kane, R.S., Dordick, J.S., Friedman, J.M.: Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nat. Med. 21, 92–98 (2014)CrossRef

43.

Stanley, S.A., Kelly, L., Latcha, K.N., Schmidt, S.F., Yu, X., Nectow, A.R., Sauer, J., Dyke, J.P., Dordick, J.S., Friedman, J.M.: Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism. Nature. 531(7596), 647–650 (2016)CrossRef

44.

Wheeler, M.A., Smith, C.J., Ottolini, M., Barker, B.S., Purohit, A.M., Grippo, R.M., Gaykema, R.P., Spano, A.J., Beenhakker, M.P., Kucenas, S., et al.: Genetically targeted magnetic control of the nervous system. Nat. Neurosci. 19(5), 756–761 (2016)CrossRef

45.

Hudspeth, A.J.: Making an effort to listen: mechanical amplification in the ear. Neuron. 59, 530–545 (2008)CrossRef

46.

Delmas, P., Coste, B.: Mechano-gated ion channels in sensory systems. Cell. 155, 278–284 (2013)CrossRef

47.

Pravettoni, E., Bacci, A., Coco, S., Forbicini, P., Matteoli, M., Verderio, C.: Different localizations and functions of L-type and N-type calcium channels during development of hippocampal neurons. Dev. Biol. 227, 581–594 (2000)CrossRef

48.

Cai, D., Mataraza, J.M., Qin, Z.-H., Huang, Z., Huang, J., Chiles, T.C., Carnahan, D., Kempa, K., Ren, Z.: Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing. Nat. Methods. 2, 449–454 (2005)CrossRef

49.

Plank, C., Schillinger, U., Scherer, F., Bergemann, C., Rémy, J.S., Krötz, F., Anton, M., Lausier, J., Rosenecker, J.: The magnetofection method: using magnetic force to enhance gene delivery. Biol. Chem. 384, 737–747 (2003)CrossRef

50.

Santos, L.J., Reis, R.L., Gomes, M.E.: Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering. Trends Biotechnol. 33, 471–479 (2015)CrossRef

51.

Ito, A., Akiyama, H., Kawabe, Y., Kamihira, M.: Magnetic force-based cell patterning using Arg-Gly-Asp (RGD) peptide-conjugated magnetite cationic liposomes. J. Biosci. Bioeng. 104, 288–293 (2007)CrossRef

52.

Kriha, O., Becker, M., Lehmann, M., Kriha, D., Krieglstein, J., Yosef, M., Schlecht, S., Wehrspohn, R.B., Wendorff, J.H., Greiner, A.: Connection of hippocampal neurons by magnetically controlled movement of short electrospun polymer fibers – a route to magnetic micromanipulators. Adv. Mater. 19, 2483–2485 (2007)CrossRef

53.

Sakar, M.S., Steager, E.B., Cowley, A., Kumar, V., Pappas, G.J.: Wireless manipulation of single cells using magnetic microtransporters. In: 2011 IEEE International Conference on Robotics and Automation, pp. 2668–2673. IEEE, Shanghai (2011)CrossRef

54.

Xie, J., Chen, L., Varadan, V.K., Yancey, J., Srivatsan, M.: The effects of functional magnetic nanotubes with incorporated nerve growth factor in neuronal differentiation of PC12 cells. Nanotechnology. 19, 105101 (2008)CrossRef

55.

Fischer, T.M., Steinmetz, P.N., Odde, D.J.: Robust micromechanical neurite elicitation in synapse-competent neurons via magnetic bead force application. Ann. Biomed. Eng. 33, 1229–1237 (2005)CrossRef

56.

Mannix, R.J., Kumar, S., Cassiola, F., Montoya-Zavala, M., Feinstein, E., Prentiss, M., Ingber, D.E.: Nanomagnetic actuation of receptor-mediated signal transduction. Nat. Nanotechnol. 3, 36–40 (2008)CrossRef

57.

Tyler, W.J.: The mechanobiology of brain function. Nat. Rev. Neurosci. 13, 867–878 (2012)CrossRef

58.

Rosenberg, S.S., Spitzer, N.C.: Calcium signaling in neuronal development. Cold Spring Harb. Perspect. Biol. 3, 1–13 (2011)CrossRef

59.

Perlmutter, J.S., Mink, J.W.: Deep brain stimulation. Annu. Rev. Neurosci. 29, 229–257 (2006)CrossRef

60.

Matthews, B.D., Lavan, D.A., Overby, D.R., Karavitis, J., Ingber, D.E.: Electromagnetic needles with submicron pole tip radii for nanomanipulation of biomolecules and living cells. Appl. Phys. Lett. 85, 2968–2970 (2004)CrossRef

61.

Carvalho-de-Souza, J.L., Treger, J.S., Dang, B., Kent, S.B.H., Pepperberg, D.R., Bezanilla, F.: Photosensitivity of neurons enabled by cell-targeted gold nanoparticles. Neuron. 86, 207–217 (2015)CrossRef

62.

Summers, H.D., Rees, P., Holton, M.D., Brown, M.R., Chappell, S.C., Smith, P.J., Errington, R.J.: Statistical analysis of nanoparticle dosing in a dynamic cellular system. Nat. Nanotechnol. 6, 170–174 (2011)CrossRef

63.

Jiang, W., Kim, B.Y.S., Rutka, J.T., Chan, W.C.W.: Nanoparticle-mediated cellular response is size-dependent. Nat. Nanotechnol. 3, 145–150 (2008)CrossRef

64.

Grünberg, K., Wawer, C., Tebo, B.M., Schüler, D.: A large gene cluster encoding several magnetosome proteins is conserved in different species of magnetotactic bacteria. Appl. Environ. Microbiol. 67, 4573–4582 (2001)CrossRef

65.

Chen, T.-W., Wardill, T.J., Sun, Y., Pulver, S.R., Renninger, S.L., Baohan, A., Schreiter, E.R., Kerr, R.A., Orger, M.B., Jayaraman, V., et al.: Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature. 499, 295–300 (2013)CrossRef

66.

Eggeman, A.S., Majetich, S.A., Farrell, D., Pankhurst, Q.A.: Size and concentration effects on high frequency hysteresis of iron oxide nanoparticles. IEEE Trans. Magn. 43, 2451–2453 (2007)CrossRef

67.

Cole, A.J., David, A.E., Wang, J., Galbán, C.J., Hill, H.L., Yang, V.C.: Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting. Biomaterials. 32, 2183–2193 (2011)CrossRef

68.

Kong, S.D., Zhang, W., Lee, J.H., Brammer, K., Lal, R., Karin, M., Jin, S.: Magnetically vectored nanocapsules for tumor penetration and remotely switchable on-demand drug release. Nano Lett. 10, 5088–5092 (2010)CrossRef

Title: Acute Neural Stimulation
Author: Andy Kah Ping Tay
Publisher: Springer International Publishing
Book: Acute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels
Print ISBN: 978-3-319-69058-2

Electronic ISBN: 978-3-319-69059-9

Copyright Year: 2018
DOI: https://doi.org/10.1007/978-3-319-69059-9_2