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Biophysical Characterization of Aptamer-Target Interactions Read chapter Read first chapter

2020 | OriginalPaper | Chapter

Aptamer-Modified Nanoparticles in Medical Applications

Authors : Alina Eilers, Sandra Witt, Johanna Walter

Published in: Aptamers in Biotechnology

Publisher: Springer International Publishing

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Abstract

Since aptamers have been selected against a broad range of target structures of medical interest and nanoparticles are available with diverse properties, aptamer-modified nanoparticles can be used in various diagnostic and therapeutic applications. While the aptamer is responsible for specificity and affinity of the conjugate, the nanoparticles’ function varies from signal generation in diagnostic approaches to drug loading in drug delivery systems. Within this chapter different medical applications of aptamer-modified nanoparticles will be summarized and underlying principles will be described.

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previous chapter Aptamers in Diagnostic and Molecular Imaging Applications
next chapter Defining Target Product Profiles (TPPs) for Aptamer-Based Diagnostics
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Metadata
Title
Aptamer-Modified Nanoparticles in Medical Applications
Authors
Alina Eilers
Sandra Witt
Johanna Walter
Copyright Year
2020
Book
Aptamers in Biotechnology

Print ISBN: 978-3-030-54060-9

Electronic ISBN: 978-3-030-54061-6

Copyright Year: 2020

DOI
https://doi.org/10.1007/10_2020_124

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