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Published in: Microsystem Technologies 4/2016

26-05-2015 | Technical Paper

Au decorated ZnO thin film: application to DNA sensing

Authors: K. L. Foo, U. Hashim, C. H. Voon, Mohammad Kashif, Md. Eaqub Ali

Published in: Microsystem Technologies | Issue 4/2016

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Abstract

Here we reported the gold nanoparticles (GNPs) decorated ZnO thin films based biosensor for the detection of pork DNA hybridization. Label-free DNA detection is increasingly important in bio diagnostics, food analysis and forensic investigations. The capacitance, permittivity and impedance profiles of the biosensor clearly differentiated the complementary and non-complementary target DNA detection using low-cost dielectric analyzer. In this study, GNPs were used to create an attachment surface between the ZnO thin films and the thiol-modified probe DNA and to enhance the sensitivity of the biosensor up to ~59 %. The ZnO thin films and 35 ± 5 nm in diameters of GNP-coating on their surfaces were confirmed with various types of measurement such as FESEM, XRD, EDX and UV–Vis spectroscopy.

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Metadata
Title
Au decorated ZnO thin film: application to DNA sensing
Authors
K. L. Foo
U. Hashim
C. H. Voon
Mohammad Kashif
Md. Eaqub Ali
Publication date
26-05-2015
Publisher
Springer Berlin Heidelberg
Published in
Microsystem Technologies / Issue 4/2016
Print ISSN: 0946-7076
Electronic ISSN: 1432-1858
DOI
https://doi.org/10.1007/s00542-015-2572-x

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