Skip to main content
Disciplines
Automotive Business IT + Informatics Construction + Real Estate Electrical Engineering + Electronics Energy + Sustainability Insurance + Risk Finance + Banking Management + Leadership Marketing + Sales Mechanical Engineering + Materials
Events
DE
EN
Books
Journals
Topic Page
Marketing
Start single access now
Access for companies
EXTENDED SEARCH
Log in
Top
Published in:
Basic Principles of Solid-State X-Ray Radiation Detector Operation Read chapter Read first chapter

2023 | OriginalPaper | Chapter

20. Electrochemiluminescent Biosensors Based on II–VI Quantum Dots

Authors : Xiao-Yan Wang, Zhi-Yuan Che, Shou-Nian Ding

Published in: Handbook of II-VI Semiconductor-Based Sensors and Radiation Detectors

Publisher: Springer International Publishing

Log in

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

II–VI semiconductor quantum dots (QDs) have attracted much attention due to their wideband absorption, narrowband emission, and continuously adjustable wavelength. In recent decades, electrochemiluminescence (ECL) biosensor related to II-VI semiconductor quantum dots has shown broad development prospects and made great achievements. Deep insight into the applications of II–VI semiconductor quantum dots in ECL biosensing platforms will benefit the design of advanced biosensors in the future. This chapter will briefly summarize the ECL mechanism of II–VI semiconductor quantum dots, the ECL signal transduction strategies, and the application of II–VI semiconductor quantum dots in biosensors such as immunosensor, aptasensor, genosensor, and molecularly imprinted polymer-based sensor. Furthermore, recent developments of ECL biosensors, relevant signal amplification methodologies, and an outlook for the construction of highly sensitive ECL biosensors based on various II–VI semiconductor quantum dots are also discussed.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

inform now
previous chapter QDs-Based Chemiluminescence Biosensors
next chapter Electrochemical Biosensors
Literature
1.
Ma XG, Gao WY, Du FX, Yuan F, Yu J, Guan YR, et al. Rational design of electrochemiluminescent devices. Acc Chem Res. 2021;54(14):2936–45.CrossRef
2.
Miao WJ. Electrogenerated chemiluminescence and its biorelated applications. Chem Rev. 2008;108(7):2506–53.CrossRef
3.
Peng H, Huang Z, Sheng Y, Zhang X, Liu J. Pre-oxidation of gold nanoclusters results in a 66% anodic electrochemiluminescence yield and drives mechanistic insights. Angew Chem Int Ed. 2019;58(34):11691–4.CrossRef
4.
Chen MY, Ning ZQ, Chen KY, Zhang YJ, Shen YF. Recent advances of electrochemiluminescent system in bioassay. J Anal Test. 2020;4(2):57–75.CrossRef
5.
Lu HJ, Xu JJ, Zhou H, Chen HY. Recent advances in electrochemiluminescence resonance energy transfer for bioanalysis: fundamentals and applications. Trac-Trends Analyt Chem. 2020;122:115746.CrossRef
6.
Wang FF, Liu YQ, Fu CP, Li N, Du M, Zhang LN, et al. Paper-based bipolar electrode electrochemiluminescence platform for detection of multiple miRNAs. Anal Chem. 2021;93(3):1702–8.CrossRef
7.
Liu ZY, Qi WJ, Xu GB. Recent advances in electrochemiluminescence. Chem Soc Rev. 2015;44:3117–42.CrossRef
8.
Zhou Y, Chen SH, Luo XL, et al. Ternary electrochemiluminescence nanostructure of Au nanoclusters as a highly efficient signal label for ultrasensitive detection of cancer biomarkers. Anal Chem. 2018;90(16), 10:024–30.
9.
Habtamu HB, Sentic M, Silvestrini M, De Leo L, Not T, Arbault S, Manojlovic D, Sojic N, et al. A sensitive electrochemiluminescence immunosensor for celiac disease diagnosis based on nanoelectrode ensembles. Anal Chem. 2015;87(24):12080–7.CrossRef
10.
Rusling JF, Forster RJ. Biosensors designed for clinical applications. Biomedicines. 2021;9(7):702.CrossRef
11.
Zhao CQ, Zhou J, Wu K-W, Ding SN, Xu JJ, Chen HY. Plasmonic enhanced gold nanoclusters-based photoelectrochemical biosensor for sensitive alkaline phosphatase activity analysis. Anal Chem. 2020;92(10):6886–92.CrossRef
12.
Zhao CQ, Ding SN, Xu JJ, Chen HY. ZnAgInS quantum dot-decorated BiOI heterostructure for cathodic photoelectrochemical bioanalysis of glucose oxidase. Acs Appl Nano Mater. 2020;3(11):11489–96.CrossRef
13.
Zhao CQ, Ding SN. Perspective on signal amplification strategies and sensing protocols in photoelectrochemical immunoassay. Coord Chem Rev. 2019;391:1–14.CrossRef
14.
Liu JX, Liang XL, Chen F, Ding SN. Ultrasensitive amperometric cytosensor for drug evaluation with monitoring early cell apoptosis based on Cu2O@PtPd nanocomposite as signal amplified label. Sensors Actuators B Chem. 2019;300:127046.CrossRef
15.
Liu JX, Bao N, Luo X, Ding SN. Nonenzymatic amperometric aptamer cytosensor for ultrasensitive detection of circulating tumor cells and dynamic evaluation of cell surface N-glycan expression. Acs Omega. 2018;3(8):8595–604.CrossRef
16.
Zuo JY, Jiao YJ, Zhu J, Ding SN. Rapid detection of severe fever with Thrombocytopenia syndrome virus via colloidal gold immunochromatography assay. Acs Omega. 2018;3(11):15399–406.CrossRef
17.
Wang XY, Zhu KD, Zhu J, Ding SN. Photonic crystal of polystyrene nanomembrane: signal amplification and low triggered potential electrochemiluminescence for tetracycline detection. Anal Chem. 2021;93(5):2959–67.CrossRef
18.
Wang XY, Wu MX, Ding SN. Anodic electrochemiluminescence from CsPbBr3 perovskite quantum dots for an alkaline phosphatase assay. Chem Commun. 2020;56(58):8099–102.CrossRef
19.
Li ZZ, Wu MX, Ding SN. Anodic near-infrared electrochemiluminescence from Cu-doped CdTe quantum dots for tetracycline detection. Anal Methods. 2021;13(20):2297–304.CrossRef
20.
Zhang S, Liu Y. Recent progress of novel electrochemiluminescence nanoprobes and their analytical applications. Front Chem. 2021;8:626243.CrossRef
21.
Rahn KL, Anand RK. Recent advancements in bipolar electrochemical methods of analysis. Anal Chem. 2021;93(1):103–23.CrossRef
22.
Du F, Chen Y, Meng C, Lou B, Zhang W, Xu G. Recent advances in electrochemiluminescence immunoassay based on multiple-signal strategy. Curr Opin Electrochem. 2021;28:100725.CrossRef
23.
Ding ZF, Quinn BM, Haram SK, Pell LE, Korgel BA, Bard AJ. Electrochemistry and electrogenerated chemiluminescence from silicon nanocrystal quantum dots. Science. 2002;296(5571):1293–7.CrossRef
24.
Abdussalam A, Xu G. Recent advances in electrochemiluminescence luminophores. Anal Bioanal Chem. 2022;414(1):131–46.CrossRef
25.
Brus LE. Electron-electron and electron-hole interactions in small semiconductor crystallites: the size dependence of the lowest excited electronic state. J Chem Phys. 1984;80(9):4403–9.CrossRef
26.
Qi H, Wang S, Jiang X, Fang Y, Wang A, Shen H, et al. Research progress and challenges of blue light-emitting diodes based on II-VI semiconductor quantum dots. J Mater Chem C. 2020;8(30):10160–73.CrossRef
27.
Peng X. An essay on synthetic chemistry of colloidal nanocrystals. Nano Res. 2009;2(6):425–47.CrossRef
28.
Zhou J, Zhu M, Meng R, Qin H, Peng X. Ideal CdSe/CdS core/shell nanocrystals enabled by entropic ligands and their core size-, shell thickness-, and ligand-dependent photoluminescence properties. J Am Chem Soc. 2017;139(46):16556.CrossRef
29.
Chen O, Zhao J, Chauhan VP, Jian C, Wong C, Harris DK, et al. Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking. Nat Mater. 2013;12(5):445–51.CrossRef
30.
Martinez-Perinan E, Gutierrez-Sanchez C, Garcia-Mendiola T, Lorenzo E. Electrochemiluminescence biosensors using screen-printed electrodes. Bios. 2020;10(9):118.
31.
Zhang Q, Zhang X, Ma Q. Recent advances in visual electrochemiluminescence analysis. Anal Test. 2020;4(2):92–106.CrossRef
32.
Feng L, Hua C, Lin X. Potential-resolved electrochemiluminescence of Ru(bpy)32+/C2O42−system on gold electrode. Luminescence. 2002;17(2):117–22.CrossRef
33.
Liang XL, Bao N, Luo X, Ding SN. CdZnTeS quantum dots based electrochemiluminescent image immunoanalysis. Biosens Bioelectron. 2018;117:145–52.CrossRef
34.
Zhu HY, Ding SN. Dual-signal-amplified electrochemiluminescence biosensor for microRNA detection by coupling cyclic enzyme with CdTe QDs aggregate as luminophor. Biosens Bioelectron. 2019;134:109–16.CrossRef
35.
Shan Y, Zhang HL, Zhu Y, Wang Y, Song HJ, Shi CG. Electrochemiluminescent CdTe nanocrystal/reduced graphene oxide composite films for the detection of diethylstilbestrol. ACS Appl Nano Mater. 2020;3(5):4670–80.CrossRef
36.
Du DX, Shu JN, Guo MQ, Haghighatbin MA, Yang D, Bian ZP, et al. Potential-resolved differential electrochemiluminescence immunosensor for cardiac troponin I based on MOF-5-wrapped CdS quantum dot nanoluminophores. Anal Chem. 2020;92(20):14113–21.CrossRef
37.
Dai PP, Liu C, Xie CG, Ke JJ, He Y, Wei LY, et al. TiO2 nanotubes loaded with CdS nanocrystals as enhanced emitters of electrochemiluminescence: application to an assay for prostate-specific antigen. Anal Bioanal Chem. 2020;412(6):1375–84.CrossRef
38.
Hu L, Wu Y, Xu M, Gu W, Zhu C. Recent advances in co-reaction accelerators for sensitive electrochemiluminescence analysis. Chem Commun. 2020;56(75):10989–99.CrossRef
39.
Craw P, Balachandran W. Isothermal nucleic acid amplification technologies for point-of-care diagnostics: a critical review. Lab Chip. 2012;12(14):2469–86.CrossRef
40.
Liu Q, Xie XL, Mao CJ, Chen JS, Niu HL, Song JM. Electrochemiluminescent biosensor with DNA link for selective detection of human IgG based on steric hindrance. Talanta. 2019;194:745–51.CrossRef
41.
Achermann M, Petruska MA, et al. Energy-transfer pumping of semiconductor nanocrystals using an epitaxial quantum well. Nature. 2004;429(6992):642–6.CrossRef
42.
Zhang H, Zhang C, Liu D, Zuo FM, Chen SH, Yuan R, et al. A ratiometric electrochemiluminescent biosensor for Con A detecting based on competition of dissolved oxygen. Biosens Bioelectron. 2018;120:40–6.CrossRef
43.
Feng QM, Shen YZ, Li MX, Zhang ZL, Zhao W, Xu JJ, et al. Dual-wavelength electrochemiluminescence ratiometry based on resonance energy transfer between Au nanoparticles functionalized g-C3N4 nanosheet and Ru(bpy)32+ for microRNA detection. Anal Chem. 2016;88(1):937–44.CrossRef
44.
Lu HJ, Zhao W, Xu JJ, Chen HY. Visual electrochemiluminescence ratiometry on bipolar electrode for bioanalysis. Biosens Bioelectron. 2018;102:624–30.CrossRef
45.
Dong H, Han TT, Ren LL, Ding SN. Novel sandwich-structured electrochemiluminescence immunosensing platform via CdTe quantum dots-embedded mesoporous silica nanospheres as enhanced signal labels and Fe3O4@SiO2@PS nanocomposites as magnetic separable carriers. J Electroanal Chem. 2017;806:32–40.CrossRef
46.
Ren LL, Dong H, Han TT, Chen Y, Ding SN. Enhanced anodic electrochemiluminescence of CdTe quantum dots based on electrocatalytic oxidation of a co-reactant by dendrimer-encapsulated Pt nanoparticles and its application for sandwiched immunoassays. Analyst. 2017;142(20):3934–41.CrossRef
47.
Babamiri B, Hallaj R, Salimi A. Ultrasensitive electrochemiluminescence immunosensor for determination of hepatitis B virus surface antigen using CdTe@CdS-PAMAM dendrimer as luminescent labels and Fe3O4 nanoparticles as magnetic beads. Sensors Actuators B Chem. 2018;254:551–60.CrossRef
48.
Zhang HJ, Zhu J, Bao N, Ding SN. Enhanced electrochemiluminescence of CdS quantum dots capped with mercaptopropionic acid activated by EDC for Zika virus detection dagger. Analyst. 2021;246(9):2928–35.CrossRef
49.
Zhang JJ, Liu WJ, Gong W, Liu N, Jia YT, Ding D, et al. Ultrasensitive determination of Microcystin-Leucine-Arginine (MCLR) by an Electrochemiluminescence (ECL) immunosensor with graphene nanosheets as a scaffold for cadmium-selenide quantum dots (QDs). Anal Lett. 2021;54(16):2523–36.CrossRef
50.
Chen WL, Zhu Q, Tang QH, Zhao K, Deng AP, Li JG. Ultrasensitive detection of diclofenac based on electrochemiluminescent immunosensor with multiple signal amplification strategy of palladium attached graphene oxide as bioprobes and ceria doped zinc oxide as substrates. Sensors Actuators B Chem. 2018;268:411–20.CrossRef
51.
Chen WL, Zhou R, Yao X, Zhao K, Deng AP, Li JG. Sensitive detection of enrofloxacin using an electrochemiluminescence immunosensor based on gold-functionalized C-60 and Au@BSA nanoflowers. New J Chem. 2018;42(17):14142–8.CrossRef
52.
Shi ZX, Li GK, Hu YF. Progress on the application of electrochemiluminescence biosensor based on nanomaterials. Chin Chem Lett. 2019;30(9):1600–6.CrossRef
53.
Wang C, Chen M, Wu JL, Mo FJ, Fu YZ. Multi-functional electrochemiluminescence aptasensor based on resonance energy transfer between Au nanoparticles and lanthanum ion-doped cadmium sulfide quantum dots. Anal Chim Acta. 2019;1086:66–74.CrossRef
54.
Babamiri B, Salimi A, Hallaj R. Switchable electrochemiluminescence aptasensor coupled with resonance energy transfer for selective attomolar detection of Hg2+ via CdTe@CdS/dendrimer probe and Au nanoparticle quencher. Biosens Bioelectron. 2018;102:328–35.CrossRef
55.
Feng DF, Li PH, Tan XC, Yeyu W, Wei FC, Du FK, et al. Electrochemiluminescence aptasensor for multiple determination of Hg2+ and Pb2+ ions by using the MIL-53(Al)@CdTe-PEI modified electrode. Anal Chim Acta. 2020;1100:232–9.CrossRef
56.
Liu JH, Chen PP, Xia FQ, Liu Z, Liu HB, Yi JL, et al. Sensitive electrochemiluminescence aptasensor for chlorpyrifos detection based on resonance energy transfer between MoS2/CdS nanospheres and Ag/CQDs. Sensors Actuators B Chem. 2020;315:128098.CrossRef
57.
Gao JW, Chen ZY, Mao LB, Zhang W, Wen W, Zhang XH, et al. Electrochemiluminescent aptasensor based on resonance energy transfer system between CdTe quantum dots and cyanine dyes for the sensitive detection of Ochratoxin A. Talanta. 2019;199:178–83.CrossRef
58.
Wei M, Wang CL, Xu ES, Chen J, Xu XL, Wei W, et al. A simple and sensitive electrochemiluminescence aptasensor for determination of ochratoxin A based on a nicking endonuclease-powered DNA walking machine. Food Chem. 2019;282:141–6.CrossRef
59.
Feng DF, Tan XC, Wu YY, Ai CH, Luo YN, Chen QY, et al. Electrochemiluminescence nanogears aptasensor based on MIL-53(Fe)@CdS for multiplexed detection of kanamycin and neomycin. Biosens Bioelectron. 2019;129:100–6.CrossRef
60.
Cao JT, Wang YL, Wang JB, Zhou QM, Ma SH, Liu YM. An electrochemiluminescence ratiometric self-calibrated biosensor for carcinoembryonic antigen detection. J Electroanal Chem. 2018;814:111–7.CrossRef
61.
Ding CF, Li YX, Wang L, Luo XL. Ratiometric electrogenerated chemiluminescence cytosensor based on conducting polymer hydrogel loaded with internal standard molecules. Anal Chem. 2019;91(1):983–9.CrossRef
62.
Tan L, Ge JJ, Jiao M, Jie GF, Niu SY. Amplified electrochemiluminescence detection of DNA based on novel quantum dots signal probe by multiple cycling amplification strategy. Talanta. 2018;183:108–13.CrossRef
63.
Dong YP, Gao TT, Zhou Y, Jiang LP, Zhu JJ. Anodic electrogenerated chemiluminescence of Ru(bpy)32+ with CdSe quantum dots as coreactant and its application in quantitative detection of DNA. Sci Rep. 2015;5:15392.CrossRef
64.
Lu LP, Wu J, Li M, Kang TF, Cheng SY. Detection of DNA damage by exploiting the distance dependence of the electrochemiluminescence energy transfer between quantum dots and gold nanoparticles. Microchim Acta. 2015;182(1–2):233–9.CrossRef
65.
Jie GF, Qin YQ, Meng QM, Wang JL. Autocatalytic amplified detection of DNA based on a CdSe quantum dot/folic acid electrochemiluminescence energy transfer system. Analyst. 2015;140(1):79–82.CrossRef
66.
Sun MF, Liu JL, Chai YQ, Zhang J, Tang Y, Yuan R. Three-dimensional cadmium telluride quantum dots-DNA nanoreticulation as a highly efficient electrochemiluminescent emitter for ultrasensitive detection of microRNA from cancer cells. Anal Chem. 2019;91(12):7765–73.CrossRef
67.
Xu ZQ, Liao LL, Chai YQ, Wang HJ, Yuan R. Ultrasensitive electrochemiluminescence biosensor for microRNA detection by 3D DNA walking machine based target conversion and distance-controllable signal quenching and enhancing. Anal Chem. 2017;89(16):8282–7.CrossRef
68.
Peng LC, Zhang P, Chai YQ, Yuan R. Bi-directional DNA walking machine and its application in an enzyme-free electrochemiluminescence biosensor for sensitive detection of microRNAs. Anal Chem. 2017;89(9):5036–42.CrossRef
69.
Li SH, Ma XH, Pang CH, Li HB, Liu CH, Xu Z, et al. Novel molecularly imprinted amoxicillin sensor based on a dual recognition and dual detection strategy. Anal Chim Acta. 2020;1127:69–78.CrossRef
70.
Zhao WR, Kang TF, Xu YH, Zhang X, Liu H, Ming AJ, et al. Electrochemiluminescence solid-state imprinted sensor based on graphene/CdTe@ZnS quantum dots as luminescent probes for low-cost ultrasensing of diethylstilbestrol. Sensors Actuators B Chem. 2020;306:127563.CrossRef
71.
Wang ZH, Qian YX, Wei XL, Zhang YF, Wu GF, Lu XQ. An “on-off” electrochemiluminescence biosensor based on molecularly imprinted polymer and recycling amplifications for determination of dopamine. Electrochim Acta. 2017;250:309–19.CrossRef
72.
Cao N, Zhao FQ, Zeng BZ. A novel self-enhanced electrochemiluminescence sensor based on PEI-CdS/Au@SiO2@RuDS and molecularly imprinted polymer for the highly sensitive detection of creatinine. Sensors Actuators B Chem. 2020;306:127591.CrossRef
73.
Zhao W, Chen HY, Xu JJ. Electrogenerated chemiluminescence detection of single entities. Chem Sci. 2021;12(16):5720–36.CrossRef
Metadata
Title
Electrochemiluminescent Biosensors Based on II–VI Quantum Dots
Authors
Xiao-Yan Wang
Zhi-Yuan Che
Shou-Nian Ding
Copyright Year
2023
Book
Handbook of II-VI Semiconductor-Based Sensors and Radiation Detectors

Print ISBN: 978-3-031-23999-1

Electronic ISBN: 978-3-031-24000-3

Copyright Year: 2023

DOI
https://doi.org/10.1007/978-3-031-24000-3_20

Premium Partners

    Image Credits