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Erschienen in:
2015 | OriginalPaper | Buchkapitel
A Mechanically Stimulated Fracture Healing Model Using a Finite Element Framework
verfasst von : Alexander Sapotnick, Udo Nackenhorst
Erschienen in: Biomedical Technology
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Abstract
In this work a biochemical fracture healing model coupled with mechanical stimulation of stem cell differentiation is investigated. A finite element scheme is applied to the underlaying advection-diffusion-reaction problem, using the Time Discontinuous Galerkin and Finite Calculus method to ensure stability of the calculation. Strains within the callus region are computed and used for a characterization of the local mechanical demand and the resulting stimulation of the healing process. A theoretical axisymmetric model of a sheep osteotomy is implemented and results of the presented FEM approach are discussed. The repair progress will be determined by the interfragmentary movement (IFM) and the mean tissue densities.