Skip to main content

2020 | OriginalPaper | Buchkapitel

A Method to Automate the Metabolite Postprocessing and Quantification on Magnetic Resonance Spectroscopy Signals

verfasst von : Francisco López-Caracheo, Carlos Andres Perez-Ramírez, Arturo Hernández-Medina, Roberto E. Mercadillo-Caballero, Erick H. Pasaye-Alcaraz

Erschienen in: VIII Latin American Conference on Biomedical Engineering and XLII National Conference on Biomedical Engineering

Verlag: Springer International Publishing

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

In this paper, an automatic method to process and quantify the metabolites of a magnetic resonance spectroscopy signal is presented. Signals obtained from a region of the left thalamus were analyzed. The obtained results were compared with the ones obtained using a Phillips’ commercial magnetic resonance software. Three features of the signal corresponding to five different metabolites (NAA, Cr, Cho, Glx, Cr2) were obtained: width, height and area of the curve corresponding to each peak. The obtained results showed a maximum relative error of over 20%, indicating the potential that the proposal has. Further refinements are required to reduce the error.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Verma, A., Kumar, I., Verma, N., Aggarwal, P., Ojha, R.: Magnetic resonance spectroscopy - revisiting the biochemical and molecular milieu of brain tumors. BBA Clin. 5, 170–178 (2016)CrossRef Verma, A., Kumar, I., Verma, N., Aggarwal, P., Ojha, R.: Magnetic resonance spectroscopy - revisiting the biochemical and molecular milieu of brain tumors. BBA Clin. 5, 170–178 (2016)CrossRef
2.
Zurück zum Zitat Preul, M., et al.: Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy. Nat. Med. 2, 323–325 (1996)CrossRef Preul, M., et al.: Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy. Nat. Med. 2, 323–325 (1996)CrossRef
3.
Zurück zum Zitat Majós, C.: Espectroscopia por resonancia magnética de protón en el diagnóstico de tumores cerebrales. Radiologia 47, 1–2 (2005)CrossRef Majós, C.: Espectroscopia por resonancia magnética de protón en el diagnóstico de tumores cerebrales. Radiologia 47, 1–2 (2005)CrossRef
4.
Zurück zum Zitat Bustillo, J.R.: Use of proton magnetic resonance spectroscopy in the treatment of psychiatric disorders: a critical update. Dialogues Clin. Neurosci. 15, 329–337 (2013) Bustillo, J.R.: Use of proton magnetic resonance spectroscopy in the treatment of psychiatric disorders: a critical update. Dialogues Clin. Neurosci. 15, 329–337 (2013)
5.
Zurück zum Zitat Davie, C.A., et al.: Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions. Brain 117, 49–58 (1994)CrossRef Davie, C.A., et al.: Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions. Brain 117, 49–58 (1994)CrossRef
6.
Zurück zum Zitat Setzer, M., et al.: Diagnostic impact of proton MR-spectroscopy versus image-guided stereotactic biopsy. Acta Neurochir. (Wien) 149(4), 379–385 (2007)MathSciNetCrossRef Setzer, M., et al.: Diagnostic impact of proton MR-spectroscopy versus image-guided stereotactic biopsy. Acta Neurochir. (Wien) 149(4), 379–385 (2007)MathSciNetCrossRef
7.
Zurück zum Zitat Orphanidou-Vlachou, E., et al.: Metabolite levels in paediatric brain tumours correlate with histological features. Pathobiology 85(3), 157–168 (2018)CrossRef Orphanidou-Vlachou, E., et al.: Metabolite levels in paediatric brain tumours correlate with histological features. Pathobiology 85(3), 157–168 (2018)CrossRef
8.
Zurück zum Zitat Wilson, M., et al.: Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours. Eur. J. Cancer 49(2), 457–464 (2013)CrossRef Wilson, M., et al.: Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours. Eur. J. Cancer 49(2), 457–464 (2013)CrossRef
9.
Zurück zum Zitat Babourina-Brooks, B., et al.: Glycine: a non-invasive imaging biomarker to aid magnetic resonance spectroscopy in the prediction of survival in paediatric brain tumours. Oncotarget 9(27), 18858–18868 (2018)CrossRef Babourina-Brooks, B., et al.: Glycine: a non-invasive imaging biomarker to aid magnetic resonance spectroscopy in the prediction of survival in paediatric brain tumours. Oncotarget 9(27), 18858–18868 (2018)CrossRef
10.
Zurück zum Zitat Garcia Osorio, I.M.: Advanced Signal Processing for Magnetic Resonance Spectroscopy, November 2011 Garcia Osorio, I.M.: Advanced Signal Processing for Magnetic Resonance Spectroscopy, November 2011
11.
Zurück zum Zitat Lin, C., Wendt, R.E., Evans, H.J., Hedrick, T.D., Leblanc, A.D., Rowe, R.M.L.: Eddy current correction in volume- localized MR spectroscopy. J. Magn. Reson. Imaging 4, 823–827 (1994)CrossRef Lin, C., Wendt, R.E., Evans, H.J., Hedrick, T.D., Leblanc, A.D., Rowe, R.M.L.: Eddy current correction in volume- localized MR spectroscopy. J. Magn. Reson. Imaging 4, 823–827 (1994)CrossRef
12.
Zurück zum Zitat Klose, U.: In vivo proton spectroscopy in presence of eddy currents. Magn. Reson. Med. 30, 26–30 (1990)CrossRef Klose, U.: In vivo proton spectroscopy in presence of eddy currents. Magn. Reson. Med. 30, 26–30 (1990)CrossRef
14.
Zurück zum Zitat Jiru, F.: Introduction to post-processing techniques. Eur. J. Radiol. 67(2), 202–217 (2008)CrossRef Jiru, F.: Introduction to post-processing techniques. Eur. J. Radiol. 67(2), 202–217 (2008)CrossRef
15.
Zurück zum Zitat Poullet, J.B., Sima, D.M., Van Huffel, S., Van Hecke, P.: Frequency-selective quantitation of short-echo time 1H magnetic resonance spectra. J. Magn. Reson. 186(2), 293–304 (2007)CrossRef Poullet, J.B., Sima, D.M., Van Huffel, S., Van Hecke, P.: Frequency-selective quantitation of short-echo time 1H magnetic resonance spectra. J. Magn. Reson. 186(2), 293–304 (2007)CrossRef
16.
Zurück zum Zitat Keeler, J.: Fourier transformation and data processing (2004) Keeler, J.: Fourier transformation and data processing (2004)
17.
Zurück zum Zitat Chen, L., Weng, Z., Goh, L.Y., Garland, M.: An efficient algorithm for automatic phase correction of NMR spectra based on entropy minimization. J. Magn. Reson. 158(1–2), 164–168 (2002)CrossRef Chen, L., Weng, Z., Goh, L.Y., Garland, M.: An efficient algorithm for automatic phase correction of NMR spectra based on entropy minimization. J. Magn. Reson. 158(1–2), 164–168 (2002)CrossRef
18.
Zurück zum Zitat Golotvin, S., Williams, A.: Improved baseline recognition and modeling of FT NMR spectra. J. Magn. Reson. 146(1), 122–125 (2000)CrossRef Golotvin, S., Williams, A.: Improved baseline recognition and modeling of FT NMR spectra. J. Magn. Reson. 146(1), 122–125 (2000)CrossRef
19.
Zurück zum Zitat Ernst, T., Chang, L.: Data Processing and Interpretation Ernst, T., Chang, L.: Data Processing and Interpretation
Metadaten
Titel
A Method to Automate the Metabolite Postprocessing and Quantification on Magnetic Resonance Spectroscopy Signals
verfasst von
Francisco López-Caracheo
Carlos Andres Perez-Ramírez
Arturo Hernández-Medina
Roberto E. Mercadillo-Caballero
Erick H. Pasaye-Alcaraz
Copyright-Jahr
2020
DOI
https://doi.org/10.1007/978-3-030-30648-9_159

Neuer Inhalt