2005 | OriginalPaper | Buchkapitel
A Physical Model for DT-MRI Based Connectivity Map Computation
verfasst von : Erdem Yörük, Burak Acar, Roland Bammer
Erschienen in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2005
Verlag: Springer Berlin Heidelberg
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In this study we address the problem of extracting a robust connectivity metric for brain white matter. We defined the connectivity problem as an energy minimization task, by associating the DT-field to a physical system composed of nodes and springs, with their constants defined as a function of local structure. Using a variational approach we formulated a fast and stable map evolution, which utilizes an anisotropic kernel smoothing scheme equivalent to a diffusion PDE. The proposed method provides connectivity maps that correlate with normal anatomy on real patient data.