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2015 | OriginalPaper | Buchkapitel

A Public Health Model for Simulating Policy Interventions to Reduce Nonmedical Opioid Use

verfasst von : Alexandra Nielsen, Wayne Wakeland, Amanuel Zimam

Erschienen in: Simulation and Modeling Methodologies, Technologies and Applications

Verlag: Springer International Publishing

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Abstract

Reports on the development of a system dynamics simulation model of initiation and nonmedical use of pharmaceutical opioids in the US. The study relies on historical trend data as well as expert panel recommendations that inform model parameters and structure. The model was used to assess simulated public health interventions for reducing initiation and nonmedical use of opioids. Results indicate that interventions which reduce the likelihood of informal sharing of leftover medicine could significantly reduce initiation and nonmedical use. Less effective are supply restrictions, such as drug take-back days, and interventions aimed at reducing the likelihood that nonusers would decide to initiate nonmedical use based on their interactions with nonmedical users. We conclude that system dynamics is an effective approach for evaluating potential interventions to this complex system where the use of pharmaceutical opioids to treat pain can lead to unintended distal outcomes in the public sphere.

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Literatur
1.
Zurück zum Zitat Andrews JA, Hops H, Duncan SC (1997) Adolescent modeling of parent substance use: the moderating effect of the relationship with the parent. J Fam Psychol 11:259CrossRef Andrews JA, Hops H, Duncan SC (1997) Adolescent modeling of parent substance use: the moderating effect of the relationship with the parent. J Fam Psychol 11:259CrossRef
2.
Zurück zum Zitat Bates C, Laciak R, Southwick A, Bishoff J (2011) Overprescription of postoperative narcotics: a look at postoperative pain medication delivery, consumption and disposal in urological practice. J Urol 185:551–555CrossRef Bates C, Laciak R, Southwick A, Bishoff J (2011) Overprescription of postoperative narcotics: a look at postoperative pain medication delivery, consumption and disposal in urological practice. J Urol 185:551–555CrossRef
3.
Zurück zum Zitat Brownstein JS, Green TC, Cassidy TA, Butler SF (2010) Geographic information systems and pharmacoepidemiology: using spatial cluster detection to monitor local patterns of prescription opioid abuse. Pharmacoepidemiol Drug Saf 19:627–637CrossRef Brownstein JS, Green TC, Cassidy TA, Butler SF (2010) Geographic information systems and pharmacoepidemiology: using spatial cluster detection to monitor local patterns of prescription opioid abuse. Pharmacoepidemiol Drug Saf 19:627–637CrossRef
4.
Zurück zum Zitat Butler SF, Venuti SW, Benoit C, Beaulaurier RL, Houle B, Katz N (2007) Internet surveillance: content analysis and monitoring of product-specific internet prescription opioid abuse-related postings. Clin J Pain 23:619–628CrossRef Butler SF, Venuti SW, Benoit C, Beaulaurier RL, Houle B, Katz N (2007) Internet surveillance: content analysis and monitoring of product-specific internet prescription opioid abuse-related postings. Clin J Pain 23:619–628CrossRef
5.
Zurück zum Zitat Centers for Disease Control and Prevention (2012) Prescription drug abuse and overdose: public health perspective. CDC’s Primary Care and Public Health Initiative Centers for Disease Control and Prevention (2012) Prescription drug abuse and overdose: public health perspective. CDC’s Primary Care and Public Health Initiative
6.
Zurück zum Zitat Compton WM, Volkow ND (2006) Major increases in opioid analgesic abuse in the United States: concerns and strategies. Drug Alcohol Depend 81:103–108CrossRef Compton WM, Volkow ND (2006) Major increases in opioid analgesic abuse in the United States: concerns and strategies. Drug Alcohol Depend 81:103–108CrossRef
7.
Zurück zum Zitat Crum RM (2005) Epidemiology of opioid use, abuse, and dependence. Treat Opioid Depend 43 Crum RM (2005) Epidemiology of opioid use, abuse, and dependence. Treat Opioid Depend 43
8.
Zurück zum Zitat Dasgupta N, Mandl KD, Brownstein JS (2009) Breaking the news or fueling the epidemic? Temporal association between news media report volume and opioid-related mortality. PLoS ONE 4:e7758CrossRef Dasgupta N, Mandl KD, Brownstein JS (2009) Breaking the news or fueling the epidemic? Temporal association between news media report volume and opioid-related mortality. PLoS ONE 4:e7758CrossRef
10.
Zurück zum Zitat Fishbain DA, Cole B, Lewis J, Rosomoff HL, Rosomoff RS (2008) What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review. Pain Med 9:444–459CrossRef Fishbain DA, Cole B, Lewis J, Rosomoff HL, Rosomoff RS (2008) What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review. Pain Med 9:444–459CrossRef
11.
Zurück zum Zitat Food and Drug Administration (2013) Extended-release (er) and long-acting (la) opioid analgesics risk evaluation and mitigation strategy (REMS) Food and Drug Administration (2013) Extended-release (er) and long-acting (la) opioid analgesics risk evaluation and mitigation strategy (REMS)
12.
Zurück zum Zitat Fortuna RJ, Robbins BW, Caiola E, Joynt M, Halterman JS (2010) Prescribing of controlled medications to adolescents and young adults in the United States. Pediatrics 126:1108–1116CrossRef Fortuna RJ, Robbins BW, Caiola E, Joynt M, Halterman JS (2010) Prescribing of controlled medications to adolescents and young adults in the United States. Pediatrics 126:1108–1116CrossRef
13.
Zurück zum Zitat Gilson A (2012) Personal communication: findings of Madison WI drug take-back day Gilson A (2012) Personal communication: findings of Madison WI drug take-back day
14.
Zurück zum Zitat Gosin M, Marsiglia FF, Hecht ML (2003) Keepin’it REAL: a drug resistance curriculum tailored to the strengths and needs of pre-adolescents of the southwest. J Drug Educ 33:119–142CrossRef Gosin M, Marsiglia FF, Hecht ML (2003) Keepin’it REAL: a drug resistance curriculum tailored to the strengths and needs of pre-adolescents of the southwest. J Drug Educ 33:119–142CrossRef
15.
Zurück zum Zitat Governale L (2008) Outpatient drug utilization trends for oxycodone products Governale L (2008) Outpatient drug utilization trends for oxycodone products
16.
Zurück zum Zitat Hall AJ, Logan JE, Toblin RL, Kaplan JA, Kraner JC, Bixler D, Crosby AE, Paulozzi LJ (2008) Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA, J Am Med Assoc 300:2613–2620CrossRef Hall AJ, Logan JE, Toblin RL, Kaplan JA, Kraner JC, Bixler D, Crosby AE, Paulozzi LJ (2008) Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA, J Am Med Assoc 300:2613–2620CrossRef
17.
Zurück zum Zitat Johnson LD, O’Malley PM, Bachman JG, Schulenberg JE (2013) Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings, 2012. Ann Arbor Inst Soc Res Univ, Mich Johnson LD, O’Malley PM, Bachman JG, Schulenberg JE (2013) Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings, 2012. Ann Arbor Inst Soc Res Univ, Mich
18.
Zurück zum Zitat Jones CM (2013) Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers—United States, 2002–2004 and 2008–2010. Drug Alcohol Depend 132:95–100CrossRef Jones CM (2013) Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers—United States, 2002–2004 and 2008–2010. Drug Alcohol Depend 132:95–100CrossRef
19.
Zurück zum Zitat Katz NP, Birnbaum HG, Castor A (2010) Volume of prescription opioids used nonmedically in the United States. J Pain Palliat Care Pharmacother 24:141–144CrossRef Katz NP, Birnbaum HG, Castor A (2010) Volume of prescription opioids used nonmedically in the United States. J Pain Palliat Care Pharmacother 24:141–144CrossRef
20.
Zurück zum Zitat Levy MS (2007) An exploratory study of OxyContin use among individuals with substance use disorders. J Psychoact Drugs 39:271–276CrossRef Levy MS (2007) An exploratory study of OxyContin use among individuals with substance use disorders. J Psychoact Drugs 39:271–276CrossRef
21.
Zurück zum Zitat Martins SS, Keyes KM, Storr CL, Zhu H, Grucza RA (2010) Birth-cohort trends in lifetime and past-year prescription opioid-use disorder resulting from nonmedical use: results from two national surveys. J Stud Alcohol Drugs 71:480–487 Martins SS, Keyes KM, Storr CL, Zhu H, Grucza RA (2010) Birth-cohort trends in lifetime and past-year prescription opioid-use disorder resulting from nonmedical use: results from two national surveys. J Stud Alcohol Drugs 71:480–487
22.
Zurück zum Zitat Paulozzi L (2011) Vital Signs: overdoses of prescription opioid pain relievers—United States, 1999–2008 Paulozzi L (2011) Vital Signs: overdoses of prescription opioid pain relievers—United States, 1999–2008
23.
Zurück zum Zitat Rosenblum A, Parrino M, Schnoll SH, Fong C, Maxwell C, Cleland CM, Magura S, Haddox JD (2007) Prescription opioid abuse among enrollees into methadone maintenance treatment. Drug Alcohol Depend 90:64–71CrossRef Rosenblum A, Parrino M, Schnoll SH, Fong C, Maxwell C, Cleland CM, Magura S, Haddox JD (2007) Prescription opioid abuse among enrollees into methadone maintenance treatment. Drug Alcohol Depend 90:64–71CrossRef
24.
Zurück zum Zitat Sterman J (2000) Business dynamics: systems thinking and modeling for a complex world. Irwin/McGraw-Hill, Boston Sterman J (2000) Business dynamics: systems thinking and modeling for a complex world. Irwin/McGraw-Hill, Boston
25.
Zurück zum Zitat Sterman JD (2006) Learning from evidence in a complex world. J Inf 96: 505–514 Sterman JD (2006) Learning from evidence in a complex world. J Inf 96: 505–514
26.
Zurück zum Zitat Substance Abuse and Mental Health Services Administration (2006) Results from the 2005 national survey on drug use and health: national findings. Department of Health and Human Services, Rockville Substance Abuse and Mental Health Services Administration (2006) Results from the 2005 national survey on drug use and health: national findings. Department of Health and Human Services, Rockville
28.
Zurück zum Zitat Sung HE, Richter L, Vaughan R, Johnson PB, Thom B (2005) Nonmedical use of prescription opioids among teenagers in the United States: trends and correlates. J Adolesc Health 37:44–51CrossRef Sung HE, Richter L, Vaughan R, Johnson PB, Thom B (2005) Nonmedical use of prescription opioids among teenagers in the United States: trends and correlates. J Adolesc Health 37:44–51CrossRef
30.
Zurück zum Zitat Volkow ND, McLellan TA, Cotto JH, Karithanom M, Weiss SRB (2011) Characteristics of opioid prescriptions in 2009. JAMA, J Am Med Assoc 305:1299–1301CrossRef Volkow ND, McLellan TA, Cotto JH, Karithanom M, Weiss SRB (2011) Characteristics of opioid prescriptions in 2009. JAMA, J Am Med Assoc 305:1299–1301CrossRef
31.
Zurück zum Zitat Wakeland W, Fitzgerald J, Haddox JD (2010) Key data gaps for understanding trends in prescription opioid analgesic abuse and diversion among chronic pain patients and nonmedical users. Presented at the College on Problems of Drug Dependence, 72nd Annual Scientific Meeting, Scottsdale Wakeland W, Fitzgerald J, Haddox JD (2010) Key data gaps for understanding trends in prescription opioid analgesic abuse and diversion among chronic pain patients and nonmedical users. Presented at the College on Problems of Drug Dependence, 72nd Annual Scientific Meeting, Scottsdale
32.
Zurück zum Zitat Warner M, Chen LH, Makuc DM, Anderson RN, Minino AM (2011) Drug poisoning deaths in the United States, 1980–2008. Centers for Disease Control and Prevention (2011) Warner M, Chen LH, Makuc DM, Anderson RN, Minino AM (2011) Drug poisoning deaths in the United States, 1980–2008. Centers for Disease Control and Prevention (2011)
33.
Zurück zum Zitat Winkler D, Caulkins JP, Behrens DA, Tragler G (2004) Estimating the relative efficiency of various forms of prevention at different stages of a drug epidemic. Socioecon Plann Sci 38:43–56CrossRef Winkler D, Caulkins JP, Behrens DA, Tragler G (2004) Estimating the relative efficiency of various forms of prevention at different stages of a drug epidemic. Socioecon Plann Sci 38:43–56CrossRef
34.
Zurück zum Zitat Young AM, Havens JR (2012) Transition from first illicit drug use to first injection drug use among rural Appalachian drug users: a cross-sectional comparison and retrospective survival analysis. Addiction 107:587–596CrossRef Young AM, Havens JR (2012) Transition from first illicit drug use to first injection drug use among rural Appalachian drug users: a cross-sectional comparison and retrospective survival analysis. Addiction 107:587–596CrossRef
Metadaten
Titel
A Public Health Model for Simulating Policy Interventions to Reduce Nonmedical Opioid Use
verfasst von
Alexandra Nielsen
Wayne Wakeland
Amanuel Zimam
Copyright-Jahr
2015
DOI
https://doi.org/10.1007/978-3-319-11457-6_17