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Erschienen in:
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2018 | OriginalPaper | Buchkapitel

Acoustic Analysis of Mandarin Speech in Parkinson’s Disease with the Effects of Levodopa

verfasst von : Wentao Gu, Ping Fan, Weiguo Liu

Erschienen in: Studies on Speech Production

Verlag: Springer International Publishing

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Abstract

This study investigated prosodic and articulatory characteristics of parkinsonian speech by acoustic analysis of the read speech from 21 Mandarin-speaking Parkinson’s Disease (PD) patients before and after administration of levodopa medication, and 21 age- and gender-matched healthy controls (HC). PD exhibited reduced F0 variability and increased minimum intensity during the closures of stops than HC. For females, PD also showed smaller vowel space area and vowel articulation index than HC. Administration of levodopa increased the mean, the max, and the range of F0, bringing them closer to those of HC, but little effect was found on other acoustic parameters. Correlation analysis between acoustic parameters and physiological/pathological indices of PD showed that the only significant positive correlation was between pause ratio and UPDRS III score. The findings on acoustic differences between PD and HC can potentially be applied to diagnosis and speech therapy for PD.

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Metadaten
Titel
Acoustic Analysis of Mandarin Speech in Parkinson’s Disease with the Effects of Levodopa
verfasst von
Wentao Gu
Ping Fan
Weiguo Liu
Copyright-Jahr
2018
Buch
Studies on Speech Production

Print ISBN: 978-3-030-00125-4

Electronic ISBN: 978-3-030-00126-1

Copyright-Jahr: 2018

DOI
https://doi.org/10.1007/978-3-030-00126-1_19