2010 | OriginalPaper | Buchkapitel
Alpha Helix Prediction Based on Evolutionary Computation
verfasst von : Alfonso E. Márquez Chamorro, Federico Divina, Jesús S. Aguilar Ruiz, Gualberto Asencio Cortés
Erschienen in: Pattern Recognition in Bioinformatics
Verlag: Springer Berlin Heidelberg
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Multiple approaches have been developed in order to predict the protein secondary structure. In this paper, we propose an approach to such a problem based on evolutionary computation. The proposed approach considers various amino acids properties in order to predict the secondary structure of a protein. In particular, we will consider the hydrophobicity, the polarity and the charge of amino acids. In this study, we focus on predicting a particular kind of secondary structure:
α
-helices. The results of our proposal will be a set of rules that will identify the beginning or the end of such a structure.