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2020 | OriginalPaper | Buchkapitel

7. Application of Nanomaterials in the Diagnosis and Treatment of Genetic Disorders

verfasst von : Alaa A. Aljabali, Mohammad A. Obeid, Haneen A. Amawi, Meriem M. Rezigue, Yassmen Hamzat, Saurabh Satija, Murtaza M. Tambuwala

Erschienen in: Applications of Nanomaterials in Human Health

Verlag: Springer Singapore

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Abstract

Genetic testing is focused on identifying chromosome, gene, or protein changes between healthy and diseased cells or person. Genetic test outcomes can either verify or rule out possible genetic conditions and help determine whether a person is likely to develop or pass a genetic disorder. There are currently more than 1000 genetic testing and many more in the development pipeline. Therefore, the need to develop a susceptible and reliable method is vital in the diagnosis of genetic disorders. Nanomaterials offer a futuristic diagnosis platform for genetic diseases as it is a non-invasive, simple, portable, inexpensive diagnostic platform. Different nanomaterials have also been developed and functionlized with the target molecules to provide therapeutic selectively and for molecular imaging. For these reasons, the development of nanomaterials for the early detection of specific disease biomarkers in tiny amounts reaches to part-per-billion (ppb) levels, in real-time, with high sensitivity and selectivity and reliability is of great importance in disease diagnosis and disease progression monitoring. Such nanomaterials should have exceptionally high sensitivity and selectivity that combines the optical, magnetic, and electrical properties of nanomaterials with the biological selectivity and sensitivity toward their targets.

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Vorheriges Kapitel Applications of Nanomaterials in Neurological Diseases, Neuronal Differentiation, Neuronal Protection, and Neurotoxicity

Nächstes Kapitel Application of Nanomaterials in Cancer Diagnosis, Drug Delivery, and Therapy

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Titel: Application of Nanomaterials in the Diagnosis and Treatment of Genetic Disorders
verfasst von: Alaa A. Aljabali
Mohammad A. Obeid
Haneen A. Amawi
Meriem M. Rezigue
Yassmen Hamzat
Saurabh Satija
Murtaza M. Tambuwala
Verlag: Springer Singapore
Buch: Applications of Nanomaterials in Human Health
Print ISBN: 978-981-15-4801-7

Electronic ISBN: 978-981-15-4802-4

Copyright-Jahr: 2020
DOI: https://doi.org/10.1007/978-981-15-4802-4_7

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