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2019 | OriginalPaper | Buchkapitel

Barriers Towards New Medicine: Personalized and Integrative Medicine Concepts

verfasst von : Krešimir Pavelić, Željko Perdija, Sandra Kraljević Pavelić

Erschienen in: Personalized Medicine in Healthcare Systems

Verlag: Springer International Publishing

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Abstract

Technological advancements and enormous achievements in the biomedical field are presented daily. Still, everyday clinical environment lacks major breakthroughs often because of individual set-up of patients making them unique when it comes to management and treatment. A truly individual approach might therefore, transform quality of health-care and effectiveness of medicine. Implementation of such individualized medicine requires new global technologies and methods as well as a holistic view to a patient. In this paper, we discuss and present the personalized and integrative medicine paradigms as major drivers of radical changes in the system of health care that may solve some major issues that medicine faces today, i.e. globalization, new and fast growing infectious diseases, changes in behavior patterns of disease and aging population. Policy makers, health-authorities and public bodies are encouraged to enter this cross-sectorial debate and facilitate the public dialogue on such medical concept value and conditions for its success.

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Fußnoten
1
Pavelić et al. (2016).
 
2
Bošnjak et al. (2008).
 
3
Kraljević et al. (2004).
 
4
Pavelić et al. (2015).
 
5
ESF (2012).
 
6
Taw (2015).
 
7
Snyderman and Weil (2002).
 
8
McLachlan (2010).
 
9
Rees and Weil (2001).
 
10
Catchpoole et al. (2010).
 
11
The Case for Personalized medicine (2014).
 
12
Badanes et al. (2012).
 
13
Fisher (2011).
 
14
Bell et al. (2012).
 
15
Tabish (2008).
 
16
Mathie (2003).
 
17
Pan et al. (2000).
 
18
Fontanarosa and Lundberg (1998).
 
19
Kermen et al. (2010).
 
20
Spear et al. (2001).
 
21
Ezzo et al. (2005).
 
22
Randall et al. (2001).
 
23
Munkholm et al. (1999).
 
24
Davinelli et al. (2015).
 
25
Cassidy (2011).
 
26
Laycock (1936).
 
27
Goodheart et al. (2006).
 
28
Dubord (2011).
 
29
Timmermans and Mauck (2005).
 
30
Ledford (2015).
 
31
Reynolds et al. (2014).
 
32
Aspinall and Hamermesh (2007).
 
33
Carr et al. (2012).
 
34
ESF (2007).
 
35
Ring et al. (2014).
 
36
Horrigan et al. (2012).
 
37
Eisenberg et al. (1993).
 
38
This paper is supported by the Croatian Science Foundation project “5709 - Perspectives of maintaining the social state: towards the transformation of social security systems for individuals in personalized medicine” and University of Rijeka research grants 13.11.1.1.11 and 13.11.1.2.01. We acknowledge the project “Research Infrastructure for Campus-based Laboratories at University of Rijeka”, financed by European Regional Development Fund (ERDF).
 
Literatur
Zurück zum Zitat Aspinall MG, Hamermesh RG (2007) Realizing the promise of personalised medicine. Harvard Business Review. www.hbrreprints.org. October, pp 1–9 Aspinall MG, Hamermesh RG (2007) Realizing the promise of personalised medicine. Harvard Business Review. www.​hbrreprints.​org. October, pp 1–9
Zurück zum Zitat Badanes LS, Dmitrieva J, Watamura SE (2012) Understanding cortisol reactivity across the day at child care: the potential buffering role of secure attachments to caregivers. Early Child Res Q 27(1):156–165CrossRef Badanes LS, Dmitrieva J, Watamura SE (2012) Understanding cortisol reactivity across the day at child care: the potential buffering role of secure attachments to caregivers. Early Child Res Q 27(1):156–165CrossRef
Zurück zum Zitat Bell IR, Caspi O, Schwartz GE et al (2012) Integrative medicine and systemic outcomes research: issues in the emergence of a new model for primary health care. Arch Intern Med 162(2):133–140CrossRef Bell IR, Caspi O, Schwartz GE et al (2012) Integrative medicine and systemic outcomes research: issues in the emergence of a new model for primary health care. Arch Intern Med 162(2):133–140CrossRef
Zurück zum Zitat Bošnjak H, Pavelić K, Kraljević Pavelić S (2008) Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice. EMBO Rep 9:1056–1060CrossRef Bošnjak H, Pavelić K, Kraljević Pavelić S (2008) Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice. EMBO Rep 9:1056–1060CrossRef
Zurück zum Zitat Carr DF, Alfirevic A, Pirmohamed M (2012) Pharmacogenomics: current state-of-the-art. Genes 5:430–443CrossRef Carr DF, Alfirevic A, Pirmohamed M (2012) Pharmacogenomics: current state-of-the-art. Genes 5:430–443CrossRef
Zurück zum Zitat Catchpoole DR, Kennedy P, Scillicorn DR et al (2010) The curse of dimensionality: a blessing to personalized medicine. J Clin Oncol 28:e723–e724CrossRef Catchpoole DR, Kennedy P, Scillicorn DR et al (2010) The curse of dimensionality: a blessing to personalized medicine. J Clin Oncol 28:e723–e724CrossRef
Zurück zum Zitat Davinelli S, Bertoglio JC, Zarrelli A et al (2015) A randomized clinical trial evaluating the efficacy of an Anthocyanin-Maqui Berry Extract (Delphinol®) on oxidative stress biomarkers. J Am Coll Nutr 34(Suppl 1):28–33CrossRef Davinelli S, Bertoglio JC, Zarrelli A et al (2015) A randomized clinical trial evaluating the efficacy of an Anthocyanin-Maqui Berry Extract (Delphinol®) on oxidative stress biomarkers. J Am Coll Nutr 34(Suppl 1):28–33CrossRef
Zurück zum Zitat Dubord G (2011) Part 12: systematic desensitization. Can Fam Physician 57(11):1299–1299 Dubord G (2011) Part 12: systematic desensitization. Can Fam Physician 57(11):1299–1299
Zurück zum Zitat Eisenberg DM, Kessler RC, Foster C et al (1993) Unconventional medicine in the United States. Prevalence, costs, and patterns of use. N Engl J Med 328:246–252CrossRef Eisenberg DM, Kessler RC, Foster C et al (1993) Unconventional medicine in the United States. Prevalence, costs, and patterns of use. N Engl J Med 328:246–252CrossRef
Zurück zum Zitat European Science Foundation (2007) EMRC White Paper. Present status and future strategy for medical research in Europe. The positive outcome of medical research 13–14 European Science Foundation (2007) EMRC White Paper. Present status and future strategy for medical research in Europe. The positive outcome of medical research 13–14
Zurück zum Zitat European Science Foundation (2012) Forward Look: personalised medicine for the European citizen. Towards more precise medicine for the diagnosis, treatment and prevention of disease (iPM)European Science Foundation, Strasbourg European Science Foundation (2012) Forward Look: personalised medicine for the European citizen. Towards more precise medicine for the diagnosis, treatment and prevention of disease (iPM)European Science Foundation, Strasbourg
Zurück zum Zitat Ezzo J, Vickers EA, Richardson MA et al (2005) Acupuncture-point stimulation for chemotherapy-induced nausea and vomiting. Jeanette J Clin Oncol 23(28):7188–7198CrossRef Ezzo J, Vickers EA, Richardson MA et al (2005) Acupuncture-point stimulation for chemotherapy-induced nausea and vomiting. Jeanette J Clin Oncol 23(28):7188–7198CrossRef
Zurück zum Zitat Fisher J (2011) The four domains model: connecting spirituality, health and well-being. Religions 2:17–28CrossRef Fisher J (2011) The four domains model: connecting spirituality, health and well-being. Religions 2:17–28CrossRef
Zurück zum Zitat Fontanarosa FB, Lundberg GD (1998) Alternative medicine meets science. JAMA 280(18):1618–1619CrossRef Fontanarosa FB, Lundberg GD (1998) Alternative medicine meets science. JAMA 280(18):1618–1619CrossRef
Zurück zum Zitat Goodheart CD, Kazdin AE, Sternberg RJ (2006) Evidence-based psychotherapy: where practice and research meet. American Psychological Association, Washington, DC, p 296CrossRef Goodheart CD, Kazdin AE, Sternberg RJ (2006) Evidence-based psychotherapy: where practice and research meet. American Psychological Association, Washington, DC, p 296CrossRef
Zurück zum Zitat Horrigan B, Lewis S, Abrams D, Pechura C (2012) Integrative medicine in America—how integrative medicine is being practiced in clinical centers across the United States. Glob Adv Health Med 1(3):18–94CrossRef Horrigan B, Lewis S, Abrams D, Pechura C (2012) Integrative medicine in America—how integrative medicine is being practiced in clinical centers across the United States. Glob Adv Health Med 1(3):18–94CrossRef
Zurück zum Zitat Kermen R, Hickner J, Brody H, Hasham I (2010) Family physicians believe the placebo effect is therapeutic but often use real drugs as placebos. Fam Med 42(9):636–642 Kermen R, Hickner J, Brody H, Hasham I (2010) Family physicians believe the placebo effect is therapeutic but often use real drugs as placebos. Fam Med 42(9):636–642
Zurück zum Zitat Kraljević S, Stambrook PJ, Pavelić K (2004) Accelerating drug discovery. EMBO Rep 5:837–842CrossRef Kraljević S, Stambrook PJ, Pavelić K (2004) Accelerating drug discovery. EMBO Rep 5:837–842CrossRef
Zurück zum Zitat Laycock SR (1936) The relation between physiology and medicine. Can Med Assoc J 35:434–438 Laycock SR (1936) The relation between physiology and medicine. Can Med Assoc J 35:434–438
Zurück zum Zitat Mathie RT (2003) The research evidence base for homeopathy: a fresh assessment of the literature. Homeopathy 92(2):84–91CrossRef Mathie RT (2003) The research evidence base for homeopathy: a fresh assessment of the literature. Homeopathy 92(2):84–91CrossRef
Zurück zum Zitat McLachlan JC (2010) Integrative medicine and the point of credulity. Br Med J (Feature) 341:c6979CrossRef McLachlan JC (2010) Integrative medicine and the point of credulity. Br Med J (Feature) 341:c6979CrossRef
Zurück zum Zitat Munkholm H, Hansen HH, Rasmussen K (1999) Coenzyme Q10 treatment in serious heart failure. Biofactors 9:285–289CrossRef Munkholm H, Hansen HH, Rasmussen K (1999) Coenzyme Q10 treatment in serious heart failure. Biofactors 9:285–289CrossRef
Zurück zum Zitat Pan CX, Morrison RS, Ness J et al (2000) Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review. J Pain Sympt Manag 20:374–387CrossRef Pan CX, Morrison RS, Ness J et al (2000) Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review. J Pain Sympt Manag 20:374–387CrossRef
Zurück zum Zitat Pavelić K, Martinović T, Kraljević Pavelić S (2015) Do we understand the personalized medicine paradigm? EMBO Rep 16:133–136CrossRef Pavelić K, Martinović T, Kraljević Pavelić S (2015) Do we understand the personalized medicine paradigm? EMBO Rep 16:133–136CrossRef
Zurück zum Zitat Pavelić K, Sedić M, Kraljević Pavelić S (2016) Personalised medicine - the path to new medicine. In: Bodiroga-Vukobrat N, Rukavina D, Pavelic K, Sander GG (eds) Personalized medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, New York, pp 300–320 Pavelić K, Sedić M, Kraljević Pavelić S (2016) Personalised medicine - the path to new medicine. In: Bodiroga-Vukobrat N, Rukavina D, Pavelic K, Sander GG (eds) Personalized medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, New York, pp 300–320
Zurück zum Zitat Randall EM, Cynthia A et al (2001) A review of recent clinical trials of the nutritional supplement chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis. Altern Ther Health Med 7(3):79–90 Randall EM, Cynthia A et al (2001) A review of recent clinical trials of the nutritional supplement chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis. Altern Ther Health Med 7(3):79–90
Zurück zum Zitat Rees L, Weil A (2001) Integrated medicine: imbues orthodox medicine with the values of complementary medicine. Br Med J 322:119–120CrossRef Rees L, Weil A (2001) Integrated medicine: imbues orthodox medicine with the values of complementary medicine. Br Med J 322:119–120CrossRef
Zurück zum Zitat Reynolds K, Sarangi S, Bardia A, Dizon DS (2014) Precision medicine and personalized breast cancer: combination pertuzumab therapy. Pharmacogenomics Pers Med 7(1):95–105 Reynolds K, Sarangi S, Bardia A, Dizon DS (2014) Precision medicine and personalized breast cancer: combination pertuzumab therapy. Pharmacogenomics Pers Med 7(1):95–105
Zurück zum Zitat Ring M, Brodsky M, Low Dog T, Sierpina V, Bailey M, Locke A, Kogan M, Rindfleisch JA, Saper R (2014) Supplemental digital content for: developing and implementing core competencies for integrative medicine fellowships. Acad Med 89(3):1–15CrossRef Ring M, Brodsky M, Low Dog T, Sierpina V, Bailey M, Locke A, Kogan M, Rindfleisch JA, Saper R (2014) Supplemental digital content for: developing and implementing core competencies for integrative medicine fellowships. Acad Med 89(3):1–15CrossRef
Zurück zum Zitat Snyderman R, Weil AT (2002) Integrative medicine: bringing medicine back to its roots. Arch Intern Med 162(4):395–397CrossRef Snyderman R, Weil AT (2002) Integrative medicine: bringing medicine back to its roots. Arch Intern Med 162(4):395–397CrossRef
Zurück zum Zitat Spear BB, Heath-Chiozzi M, Huff J (2001) Clinical application of pharmacogenetics. Trends Mol Med 7:201–204CrossRef Spear BB, Heath-Chiozzi M, Huff J (2001) Clinical application of pharmacogenetics. Trends Mol Med 7:201–204CrossRef
Zurück zum Zitat Tabish SA (2008) Complementary and alternative healthcare: is it evidence-based? Int J Health Sci (Qassim) 2(1):5–9 Tabish SA (2008) Complementary and alternative healthcare: is it evidence-based? Int J Health Sci (Qassim) 2(1):5–9
Zurück zum Zitat Taw MB (2015) Integrative medicine, or not integrative medicine: that is the question. J Integr Med 13(6):350–352CrossRef Taw MB (2015) Integrative medicine, or not integrative medicine: that is the question. J Integr Med 13(6):350–352CrossRef
Zurück zum Zitat The Case for Personalized medicine (2014) Personalized medicine coalition, 4th edn. Washington, DC The Case for Personalized medicine (2014) Personalized medicine coalition, 4th edn. Washington, DC
Zurück zum Zitat Timmermans S, Mauck A (2005) The promises and pitfalls of evidence-based medicine. Health Aff 24(1):18–28CrossRef Timmermans S, Mauck A (2005) The promises and pitfalls of evidence-based medicine. Health Aff 24(1):18–28CrossRef
Metadaten
Titel
Barriers Towards New Medicine: Personalized and Integrative Medicine Concepts
verfasst von
Krešimir Pavelić
Željko Perdija
Sandra Kraljević Pavelić
Copyright-Jahr
2019
Verlag
Springer International Publishing
DOI
https://doi.org/10.1007/978-3-030-16465-2_19

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