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Erschienen in:
2015 | OriginalPaper | Buchkapitel
Big DNA Methylation Data Analysis and Visualizing in a Common Form of Breast Cancer
verfasst von : Islam Ibrahim Amin, Aboul Ella Hassanien, Samar K. Kassim, Hesham A. Hefny
Erschienen in: Big Data in Complex Systems
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DNA methylation is one of epigenetics mechanisms that plays a vital role in cancer research area by controlling gene expression, especially in the research of abnormally hypermethylated tumor suppressor genes or hypomethylaed oncogenes. The role of DNA methylation analysis leads to determine the significant hypermethlated or hypomethylated genes that are candidate to be cancer biomarkers also the visualization of DNA methylation status leads to discover very important relationships between hypermethylated and hypomethylated genes by using mathematical theory modeling called formal concept analysis.