Convexity and Connectivity Principles Applied for Left Ventricle Segmentation and Quantification

We propose an unsupervised method for MRI image segmentation, and global and regional shape quantification, based on pixel labeling using image analysis, connectivity constraints and near convex region requirements for the LV cavity and the epicardium. The proposed method is developed in the framework of the MICCAI Left Ventricle Full Quantification Challenge. At first the LV cavity is approximately localized based on the strong intensity contrast in the myocardium region between the two ventricles (left and right). The requirement of a near convex connected component is then applied. The image intensity statistical parameters are extracted for three classes: LV cavity, myocardium and chest space. Even if the whole background is completely inhomogeneous, the application of topological, connectivity and shape constraints permits to extract in two steps the LV cavity and the myocardium. For the later two approaches are proposed: regularization using B-spline smoothing and adaptive region growing with boundary smoothing using Fourier coefficients. On the segmented images are measured the significant clinical global and regional shape LV indices. We consider that we have obtained good results on indices related to the endocardium for both Training and Test datasets. There is place for improvements concerning the myocardium global and regional shape indices.