Skip to main content

2013 | OriginalPaper | Buchkapitel

Detection of Anatomic Structures in Retinal Images

verfasst von : José Pinão, Carlos Manta Oliveira, André Mora, João Dias

Erschienen in: Topics in Medical Image Processing and Computational Vision

Verlag: Springer Netherlands

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

A retinal image presents three important structures in a healthy eye: optic disk, fovea and blood vessels. These are diseases associated with changes in each of these structures. Some parameters should be extracted in order to evaluate if an eye is healthy. For example, the level of imperfection of the optic disk’s circle contour is related with glaucoma. Furthermore, the proximity of the lesion in the retina to the fovea (structure responsible for the central vision) induces loss of vision. Advanced stages of diabetic retinopathy cause the formation of micro blood vessels that increase the risk of detachment of the retina or prevent light from reaching the fovea. On the other hand, the arterio-venous ratio calculated through the thickness of the central vein and artery of the retina, is a parameter extracted from the vessels segmentation. In image processing, each structure detected has special importance to detect the others, since each one can be used as a landmark to the others. Moreover, often masking the optic disk is crucial to reach good results with algorithms to detect other structures. The performance of the detection algorithms is highly related with the quality of the image and with the existence of lesions. These issues are discussed below.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Jelinek HF, Cree MJ (2009) Automated image detection of retinal pathology. CRC Press, Boca RatonCrossRef Jelinek HF, Cree MJ (2009) Automated image detection of retinal pathology. CRC Press, Boca RatonCrossRef
2.
Zurück zum Zitat Davis H, Russell S, Barriga E, Abràmoff MD, Soliz P (2009) Vision-based, real-time retinal image quality assessment. Russell J Bertrand Russell Archives, pp 1–6 Davis H, Russell S, Barriga E, Abràmoff MD, Soliz P (2009) Vision-based, real-time retinal image quality assessment. Russell J Bertrand Russell Archives, pp 1–6
3.
Zurück zum Zitat Fleming AD, Philip S, Goatman KA, Olson JA, Sharp PF (2006) Automated assessment of diabetic retinal image quality based on clarity and field definition. Invest Ophthalmol Vis Sci 47:1120–1125CrossRef Fleming AD, Philip S, Goatman KA, Olson JA, Sharp PF (2006) Automated assessment of diabetic retinal image quality based on clarity and field definition. Invest Ophthalmol Vis Sci 47:1120–1125CrossRef
4.
Zurück zum Zitat Boucher MCC, Gresset JA, Angioi K, Olivier S (2003) Effectiveness and safety of screening for diabetic retinopathy with two nonmydriatic digital images compared with the seven standard stereoscopic photographic fields. Can J Ophthalmol. J canadien d’ophtalmologie. 38:557–568 Boucher MCC, Gresset JA, Angioi K, Olivier S (2003) Effectiveness and safety of screening for diabetic retinopathy with two nonmydriatic digital images compared with the seven standard stereoscopic photographic fields. Can J Ophthalmol. J canadien d’ophtalmologie. 38:557–568
5.
Zurück zum Zitat Olson JA, Sharp PF, Fleming AD, Philip S (2008) Evaluation of a System for automatic detection of diabetic retinopathy from color fundus photographs in a large population of patients with diabetes. Diabetes Care 31:e63CrossRef Olson JA, Sharp PF, Fleming AD, Philip S (2008) Evaluation of a System for automatic detection of diabetic retinopathy from color fundus photographs in a large population of patients with diabetes. Diabetes Care 31:e63CrossRef
6.
Zurück zum Zitat Zimmer-Galler I, Zeimer R (2006) Results of implementation of the DigiScope for diabetic retinopathy assessment in the primary care environment. Telemed J e-health Off J Am Telemed Assoc 12:89–98CrossRef Zimmer-Galler I, Zeimer R (2006) Results of implementation of the DigiScope for diabetic retinopathy assessment in the primary care environment. Telemed J e-health Off J Am Telemed Assoc 12:89–98CrossRef
7.
Zurück zum Zitat Philip S, Cowie LM, Olson JA (2005) The impact of the health technology board for Scotland’s grading model on referrals to ophthalmology services. Br J ophthalmol 89:891–896CrossRef Philip S, Cowie LM, Olson JA (2005) The impact of the health technology board for Scotland’s grading model on referrals to ophthalmology services. Br J ophthalmol 89:891–896CrossRef
8.
Zurück zum Zitat Heaven CJ, Cansfield J, Shaw KM (1993) The quality of photographs produced by the non-mydriatic fundus camera in a screening programme for diabetic retinopathy: a 1 year prospective study. Eye London England 7(Pt 6):787–790CrossRef Heaven CJ, Cansfield J, Shaw KM (1993) The quality of photographs produced by the non-mydriatic fundus camera in a screening programme for diabetic retinopathy: a 1 year prospective study. Eye London England 7(Pt 6):787–790CrossRef
9.
Zurück zum Zitat Abràmoff MD, Suttorp-Schulten MSA (2005) Web-based screening for diabetic retinopathy in a primary care population: the EyeCheck project. Telemed J ehealth Off J Am Telemed Assoc 11:668–674CrossRef Abràmoff MD, Suttorp-Schulten MSA (2005) Web-based screening for diabetic retinopathy in a primary care population: the EyeCheck project. Telemed J ehealth Off J Am Telemed Assoc 11:668–674CrossRef
11.
Zurück zum Zitat Lee SC, Wang Y (1999) Automatic retinal image quality assessment and enhancement. In: Proceedings of SPIE, p 1581 Lee SC, Wang Y (1999) Automatic retinal image quality assessment and enhancement. In: Proceedings of SPIE, p 1581
12.
Zurück zum Zitat Lalonde M, Gagnon L, Boucher MCC (2001) Automatic visual quality assessment in optical fundus images. In: Proceedings of Vision Interface 2001, pp 259–264 Lalonde M, Gagnon L, Boucher MCC (2001) Automatic visual quality assessment in optical fundus images. In: Proceedings of Vision Interface 2001, pp 259–264
13.
Zurück zum Zitat Bartling H, Wanger P, Martin L (2009) Automated quality evaluation of digital fundus photographs. Acta Ophthalmol 87:643–647CrossRef Bartling H, Wanger P, Martin L (2009) Automated quality evaluation of digital fundus photographs. Acta Ophthalmol 87:643–647CrossRef
14.
Zurück zum Zitat Acharya T, Ray AK (2005) Image processing: principles and applications. Wiley, Hoboken Acharya T, Ray AK (2005) Image processing: principles and applications. Wiley, Hoboken
15.
Zurück zum Zitat Hunter A, Lowell JA, Habib M, Ryder B, Basu A, Steel D (2011) An automated retinal image quality grading algorithm. In: Proceedings of the annual international conference of the IEEE engineering in medicine and biology society conference, pp 5955–5958 Hunter A, Lowell JA, Habib M, Ryder B, Basu A, Steel D (2011) An automated retinal image quality grading algorithm. In: Proceedings of the annual international conference of the IEEE engineering in medicine and biology society conference, pp 5955–5958
16.
Zurück zum Zitat Nirmala SR, Dandapat S, Bora PK (2011) Performance evaluation of distortion measures for retinal images. Int J Comput Appl 17:17 Nirmala SR, Dandapat S, Bora PK (2011) Performance evaluation of distortion measures for retinal images. Int J Comput Appl 17:17
17.
Zurück zum Zitat Niemeijer M, Abràmoff MD, van Ginneken B (2006) Image structure clustering for image quality verification of color retina images in diabetic retinopathy screening. Med Image Anal 10:888–898CrossRef Niemeijer M, Abràmoff MD, van Ginneken B (2006) Image structure clustering for image quality verification of color retina images in diabetic retinopathy screening. Med Image Anal 10:888–898CrossRef
18.
Zurück zum Zitat Giancardo L, Abràmoff MD, Chaum E, Karnowski TP, Meriaudeau F, Tobin KW (2008) Elliptical local vessel density: a fast and robust quality metric for retinal images. In: Proceedings of the international conference on IEEE engineering in medicine and biology society, pp 3534–3537 Giancardo L, Abràmoff MD, Chaum E, Karnowski TP, Meriaudeau F, Tobin KW (2008) Elliptical local vessel density: a fast and robust quality metric for retinal images. In: Proceedings of the international conference on IEEE engineering in medicine and biology society, pp 3534–3537
19.
Zurück zum Zitat Paulus J, Meier J, Bock R, Hornegger J, Michelson G (2010) Automated quality assessment of retinal fundus photos. Int J Comput Assist Radiol Surg 5:557–564CrossRef Paulus J, Meier J, Bock R, Hornegger J, Michelson G (2010) Automated quality assessment of retinal fundus photos. Int J Comput Assist Radiol Surg 5:557–564CrossRef
20.
Zurück zum Zitat Smith RT, Nagasaki T, Sparrow JR, Barbazetto I, Klaver CC, Chan JK (2003) A method of drusen measurement based on the geometry of fundus reflectance. Biomed Eng Online 2:10CrossRef Smith RT, Nagasaki T, Sparrow JR, Barbazetto I, Klaver CC, Chan JK (2003) A method of drusen measurement based on the geometry of fundus reflectance. Biomed Eng Online 2:10CrossRef
21.
Zurück zum Zitat Soliz P, Wilson MP, Nemeth SC, Nguyen P (2002) Computer-aided methods for quantitative assessment of longitudinal changes in retinal images presenting with maculopathy. In: Medical Imaging 2002: visualization, image-guided procedures, and display, SPIE, San Diego, pp 159–170 Soliz P, Wilson MP, Nemeth SC, Nguyen P (2002) Computer-aided methods for quantitative assessment of longitudinal changes in retinal images presenting with maculopathy. In: Medical Imaging 2002: visualization, image-guided procedures, and display, SPIE, San Diego, pp 159–170
22.
Zurück zum Zitat Phillips RP, Spencer T, Ross PG, Sharp PF, Forrester JV (1991) Quantification of diabetic maculopathy by digital imaging of the fundus. Eye 5(Pt 1):130–137CrossRef Phillips RP, Spencer T, Ross PG, Sharp PF, Forrester JV (1991) Quantification of diabetic maculopathy by digital imaging of the fundus. Eye 5(Pt 1):130–137CrossRef
23.
Zurück zum Zitat Jagoe JR, Blauth CI, Smith PL, Arnold JV, Taylor KM, Wootton R (1990) Quantification of retinal damage during cardiopulmonary bypass: comparison of computer and human assessment. In: Proceedings of the IEE communications, speech and vision I(137):170–175CrossRef Jagoe JR, Blauth CI, Smith PL, Arnold JV, Taylor KM, Wootton R (1990) Quantification of retinal damage during cardiopulmonary bypass: comparison of computer and human assessment. In: Proceedings of the IEE communications, speech and vision I(137):170–175CrossRef
24.
Zurück zum Zitat Rapantzikos K, Zervakis M, Balas K (2003) Detection and segmentation of drusen deposits on human retina: potential in the diagnosis of age-related macular degeneration. Med Image Anal 7:95–108CrossRef Rapantzikos K, Zervakis M, Balas K (2003) Detection and segmentation of drusen deposits on human retina: potential in the diagnosis of age-related macular degeneration. Med Image Anal 7:95–108CrossRef
25.
Zurück zum Zitat Gonzalez R, Woods R (1993) Digital image processing. Addison Wesley Publishing, New York Gonzalez R, Woods R (1993) Digital image processing. Addison Wesley Publishing, New York
26.
Zurück zum Zitat Mora AD, Vieira PM, Manivannan A, Fonseca JM (2011) Automated drusen detection in retinal images using analytical modelling algorithms. Biomed Eng Online 10:59 Mora AD, Vieira PM, Manivannan A, Fonseca JM (2011) Automated drusen detection in retinal images using analytical modelling algorithms. Biomed Eng Online 10:59
28.
Zurück zum Zitat Smith RT, Chan JK, Nagasaki T, Ahmad UF, Barbazetto I, Sparrow J, Figueroa M, Merriam J (2005) Automated detection of macular drusen using geometric background leveling and threshold selection. Arch Ophthalmol 123:200–206CrossRef Smith RT, Chan JK, Nagasaki T, Ahmad UF, Barbazetto I, Sparrow J, Figueroa M, Merriam J (2005) Automated detection of macular drusen using geometric background leveling and threshold selection. Arch Ophthalmol 123:200–206CrossRef
29.
Zurück zum Zitat Shlens J (2005) A tutorial on principal component analysis. Measurement 51:52 Shlens J (2005) A tutorial on principal component analysis. Measurement 51:52
30.
Zurück zum Zitat Newsom RS, Sinthanayothin C, Boyce J, Casswell AG, Williamson TH (2000) Clinical evaluation of “local contrast enhancement” for oral fluorescein angiograms. Eye (London, England) 14 (Pt 3A):318–23 Newsom RS, Sinthanayothin C, Boyce J, Casswell AG, Williamson TH (2000) Clinical evaluation of “local contrast enhancement” for oral fluorescein angiograms. Eye (London, England) 14 (Pt 3A):318–23
31.
Zurück zum Zitat Jobson DJ, Rahman Z, Woodell GA (1997) A multiscale retinex for bridging the gap between color images and the human observation of scenes. IEEE Trans Image Process Publ IEEE Signal Process Soc 6:965–976CrossRef Jobson DJ, Rahman Z, Woodell GA (1997) A multiscale retinex for bridging the gap between color images and the human observation of scenes. IEEE Trans Image Process Publ IEEE Signal Process Soc 6:965–976CrossRef
32.
Zurück zum Zitat Majumdar J, Nandi M, Nagabhushan P (2011) Retinex algorithm with reduced halo artifacts. Def Sci J 61:559–566 Majumdar J, Nandi M, Nagabhushan P (2011) Retinex algorithm with reduced halo artifacts. Def Sci J 61:559–566
33.
Zurück zum Zitat Land EH, McCann JJ (1971) Lightness and retinex theory. J Opt Soc Am 61:1–11CrossRef Land EH, McCann JJ (1971) Lightness and retinex theory. J Opt Soc Am 61:1–11CrossRef
34.
Zurück zum Zitat Foracchia M, Grisan E, Ruggeri A, Member S (2004) Detection of optic disc in retinal images by means of a geometrical model of vessel structure. IEEE Trans Med Imaging 2004(23):1189–1195CrossRef Foracchia M, Grisan E, Ruggeri A, Member S (2004) Detection of optic disc in retinal images by means of a geometrical model of vessel structure. IEEE Trans Med Imaging 2004(23):1189–1195CrossRef
35.
Zurück zum Zitat Hoover A, Goldbaum M (2003) Locating the optic nerve in a retinal image using the fuzzy convergence of the blood vessels. IEEE Trans Med Imaging 22:951–958CrossRef Hoover A, Goldbaum M (2003) Locating the optic nerve in a retinal image using the fuzzy convergence of the blood vessels. IEEE Trans Med Imaging 22:951–958CrossRef
36.
Zurück zum Zitat Lalonde M, Beaulieu M, Gagnon L (2001) Fast and robust optic disc detection using pyramidal decomposition and Hausdorff-based template matching. IEEE Trans Med Imaging 20:1193–1200CrossRef Lalonde M, Beaulieu M, Gagnon L (2001) Fast and robust optic disc detection using pyramidal decomposition and Hausdorff-based template matching. IEEE Trans Med Imaging 20:1193–1200CrossRef
37.
Zurück zum Zitat Youssif AR, Ghalwash AZ, Ghoneim AR (2008) Optic disc detection from normalized digital fundus images by means of a vessels’ direction matched filter. IEEE Trans Med Imaging 27:11–18 Youssif AR, Ghalwash AZ, Ghoneim AR (2008) Optic disc detection from normalized digital fundus images by means of a vessels’ direction matched filter. IEEE Trans Med Imaging 27:11–18
38.
Zurück zum Zitat Mendels F, Heneghan C, Thiran JP (1999) Identification of the optic disk boundary in retinal images using active contours. In: Proceedings of the Irish machine vision and image processing conference. Citeseer, pp 103–115 Mendels F, Heneghan C, Thiran JP (1999) Identification of the optic disk boundary in retinal images using active contours. In: Proceedings of the Irish machine vision and image processing conference. Citeseer, pp 103–115
39.
Zurück zum Zitat Osareh A, Mirmehdi M, Thomas B, Markham R (2002) Colour morphology and snakes for optic disc localisation. In: Proceedings of the 6th medical image understanding and analysis conference, pp 21–24 Osareh A, Mirmehdi M, Thomas B, Markham R (2002) Colour morphology and snakes for optic disc localisation. In: Proceedings of the 6th medical image understanding and analysis conference, pp 21–24
40.
Zurück zum Zitat Sinthanayothin C, Boyce JF, Cook HL, Williamson TH (1999) Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images. Br J Ophthalmol 83:902–910CrossRef Sinthanayothin C, Boyce JF, Cook HL, Williamson TH (1999) Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images. Br J Ophthalmol 83:902–910CrossRef
41.
Zurück zum Zitat Li H (2003) Boundary detection of optic disk by a modified ASM method. Pattern Recogn 36:2093–2104MATHCrossRef Li H (2003) Boundary detection of optic disk by a modified ASM method. Pattern Recogn 36:2093–2104MATHCrossRef
42.
Zurück zum Zitat Kavitha D, Devi SS (2005) Automatic detection of optic disc and exudates in retinal images. In: Proceedings of 2005 international conference on intelligent sensing and information processing, pp 501–506 Kavitha D, Devi SS (2005) Automatic detection of optic disc and exudates in retinal images. In: Proceedings of 2005 international conference on intelligent sensing and information processing, pp 501–506
43.
Zurück zum Zitat Sekhar S, Al-Nuaimy W, Nandi A (2008) Automated localisation of retinal optic disk using hough transform. In: Proceedings of the 5th IEEE international symposium on biomedical imaging from Nano to Macro. ISBI 2008, pp 1577–1580 Sekhar S, Al-Nuaimy W, Nandi A (2008) Automated localisation of retinal optic disk using hough transform. In: Proceedings of the 5th IEEE international symposium on biomedical imaging from Nano to Macro. ISBI 2008, pp 1577–1580
44.
Zurück zum Zitat Zhu X, Rangayyan RM (2008) Detection of the optic disc in images of the retina using the Hough transform. In: Proceedings of the Annual International Conference on the IEEE engineering in medicine and biology society, pp 3546–3549 Zhu X, Rangayyan RM (2008) Detection of the optic disc in images of the retina using the Hough transform. In: Proceedings of the Annual International Conference on the IEEE engineering in medicine and biology society, pp 3546–3549
45.
Zurück zum Zitat Cootes T (1995) Active shape models-their training and application. Comput Vis Image Underst 61:38–59CrossRef Cootes T (1995) Active shape models-their training and application. Comput Vis Image Underst 61:38–59CrossRef
46.
Zurück zum Zitat Otsu N (1979) A threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybern 9:62–66CrossRef Otsu N (1979) A threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybern 9:62–66CrossRef
47.
Zurück zum Zitat Gonzalez R, Woods R (2002) Digital image processing. Prentice Hall, Upper Saddle River Gonzalez R, Woods R (2002) Digital image processing. Prentice Hall, Upper Saddle River
48.
Zurück zum Zitat Canny J (1986) A computational approach to edge detection. IEEE Trans Pattern Anal Mach Intell PAMI-8:679–698 Canny J (1986) A computational approach to edge detection. IEEE Trans Pattern Anal Mach Intell PAMI-8:679–698
49.
Zurück zum Zitat Pinão J, Oliveira CM (2011) Fovea and optic disc detection in retinal images. In: Tavares JM, Natal Jorge RS (eds) Computational vision and medical image processing VIPIMAGE 2011. CRC Press, pp 149–153 Pinão J, Oliveira CM (2011) Fovea and optic disc detection in retinal images. In: Tavares JM, Natal Jorge RS (eds) Computational vision and medical image processing VIPIMAGE 2011. CRC Press, pp 149–153
50.
Zurück zum Zitat ter Haar F (2005) Automatic localization of the optic disc in digital colour images of the human retina. Utrecht University, The Netherlands ter Haar F (2005) Automatic localization of the optic disc in digital colour images of the human retina. Utrecht University, The Netherlands
Metadaten
Titel
Detection of Anatomic Structures in Retinal Images
verfasst von
José Pinão
Carlos Manta Oliveira
André Mora
João Dias
Copyright-Jahr
2013
Verlag
Springer Netherlands
DOI
https://doi.org/10.1007/978-94-007-0726-9_13

Neuer Inhalt