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Erschienen in:
World of Proteins: Structure-Function Relationships and Engineering Techniques Kapitel lesen Erstes Kapitel lesen

2017 | OriginalPaper | Buchkapitel

4. Generating the Fancy Protein Basket with De Novo and Combinatorial Approaches

verfasst von : Krishna Mohan Poluri, Khushboo Gulati

Erschienen in: Protein Engineering Techniques

Verlag: Springer Singapore

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Abstract

Under the umbrella of computational techniques, de novo approach occupies a unique role as this method is involved in designing the proteins from scratch. In the first part of the current chapter, we will discuss the principles and applications of the de novo approach along with negative designing technique. In the second part, we will elucidate the combinatorial approach of protein engineering, i.e., a hybrid approach to engineer proteins using both the experimental methods such as directed evolution techniques along with rational and de novo computational techniques. Furthermore, we will discuss various examples that glared the field of protein engineering under combinatorial approach.

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Vorheriges Kapitel Rational Designing of Novel Proteins Through Computational Approaches
Nächstes Kapitel Biotechnological and Biomedical Applications of Protein Engineering Methods
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Metadaten
Titel
Generating the Fancy Protein Basket with De Novo and Combinatorial Approaches
verfasst von
Krishna Mohan Poluri
Khushboo Gulati
Copyright-Jahr
2017
Verlag
Springer Singapore
Buch
Protein Engineering Techniques

Print ISBN: 978-981-10-2731-4

Electronic ISBN: 978-981-10-2732-1

Copyright-Jahr: 2017

DOI
https://doi.org/10.1007/978-981-10-2732-1_4