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Erschienen in:
Stem Cell-Based Tissue Engineering for Bone Repair Kapitel lesen Erstes Kapitel lesen

2014 | OriginalPaper | Buchkapitel

In Silico Biology of Bone Regeneration Inside Calcium Phosphate Scaffolds

verfasst von : Aurélie Carlier, Hans Van Oosterwyck, Liesbet Geris

Erschienen in: Tissue Engineering

Verlag: Springer Netherlands

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Abstract

Bone tissue engineering plays a key role in finding better solutions for the healing of large bone defects and non-unions. Despite extensive experimental research, many of the mechanisms of the bone regeneration process still remain to be elucidated. As such, mathematical modeling is a useful tool to further investigate the different influential factors and their interactions in silico. This chapter starts with a description of the biological processes that take place during bone regeneration in calcium phosphate (CaP) scaffolds. The second section gives an overview of the most recent mathematical models of bone regeneration in (CaP) scaffolds. One model is explained in more detail and used to illustrate the potential of mathematical modeling in the bone tissue engineering field. Finally, the drawbacks of the current modeling techniques and the need for more quantitative experimental research, together with possible solutions are presented.

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Vorheriges Kapitel Stem Cell-Based Tissue Engineering for Bone Repair
Nächstes Kapitel Constitutive Effects of Hydrolytic Degradation in Electro-Spun Polyester-Urethane Scaffolds for Soft Tissue Regeneration
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Metadaten
Titel
In Silico Biology of Bone Regeneration Inside Calcium Phosphate Scaffolds
verfasst von
Aurélie Carlier
Hans Van Oosterwyck
Liesbet Geris
Copyright-Jahr
2014
Verlag
Springer Netherlands
Buch
Tissue Engineering

Print ISBN: 978-94-007-7072-0

Electronic ISBN: 978-94-007-7073-7

Copyright-Jahr: 2014

DOI
https://doi.org/10.1007/978-94-007-7073-7_2

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