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Erschienen in: International Journal of Computer Assisted Radiology and Surgery 6/2021

29.03.2021 | Original Article

Intraoperative optimization of seed implantation plan in breast brachytherapy

verfasst von: Wanyu Liu, Jay Carriere, Tyler Meyer, Ron Sloboda, Siraj Husain, Nawaid Usmani, Zhiyong Yang, Mahdi Tavakoli

Erschienen in: International Journal of Computer Assisted Radiology and Surgery | Ausgabe 6/2021

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Abstract

Purpose

Low-dose-rate permanent-seed (LDR-PS) brachytherapy has shown a great potential for treating breast cancer. An implantation scheme indicating the template pose and needle trajectories is determined before the operation. However, when performing the pre-planned scheme intraoperatively, a change of the patient’s posture will cause seed placements away from the desired locations. Hence, the implantation scheme should update based on the current patient’s posture.

Methods

A numerical method of optimizing the implantation scheme for the LDR-PS breast brachytherapy is presented here. The proposed algorithm determines the fewest needle trajectories and template poses for delivering the seeds to the intraoperative desired locations. The clinical demand, such as the minimum distance between the chest wall and the needle, is considered in the optimization process.

Results

The method was simulated for a given LDR-PS brachytherapy procedure to evaluate the optimal scheme as the number of the template poses changing. The optimization parameters of the needles’ number and the implantation errors are used to adjust the algorithm outcome. The results show that the implantation schemes obtained by our method have a satisfactory accuracy in the cases of 2 or 3 template poses. The computation time is about 76s to 150s according to the number of the template poses from 1 to 3.

Conclusion

The proposed method can find the optimal implantation scheme corresponding to the current desired seed locations immediately once there is a change of patient’s posture. This work can be applied to the robot-assisted LDR-PS breast brachytherapy for improving the operation accuracy and efficiency.

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Metadaten
Titel
Intraoperative optimization of seed implantation plan in breast brachytherapy
verfasst von
Wanyu Liu
Jay Carriere
Tyler Meyer
Ron Sloboda
Siraj Husain
Nawaid Usmani
Zhiyong Yang
Mahdi Tavakoli
Publikationsdatum
29.03.2021
Verlag
Springer International Publishing
Erschienen in
International Journal of Computer Assisted Radiology and Surgery / Ausgabe 6/2021
Print ISSN: 1861-6410
Elektronische ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-021-02350-z

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