2020 | OriginalPaper | Buchkapitel
Investigation of Feature-Based Nonrigid Image Registration Using Gaussian Process
verfasst von : Siming Bayer, Ute Spiske, Jie Luo, Tobias Geimer, William M. Wells III, Martin Ostermeier, Rebecca Fahrig, Arya Nabavi, Christoph Bert, Ilker Eyüpoglo, Andreas Maier
Erschienen in: Bildverarbeitung für die Medizin 2020
Verlag: Springer Fachmedien Wiesbaden
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For a wide range of clinical applications, such as adaptive treatment planning or intraoperative image update, feature-based deformable registration (FDR) approaches are widely employed because of their simplicity and low computational complexity. FDR algorithms estimate a dense displacement field by interpolating a sparse field, which is given by the established correspondence between selected features. In this paper, we consider the deformation field as a Gaussian Process (GP), whereas the selected features are regarded as prior information on the valid deformations. Using GP, we are able to estimate the both dense displacement field and a corresponding uncertainty map at once. Furthermore, we evaluated the performance of different hyperparameter settings for squared exponential kernels with synthetic, phantom and clinical data respectively. The quantitative comparison shows, GP-based interpolation has performance on par with state-of-the-art B-spline interpolation. The greatest clinical benefit of GP-based interpolation is that it gives a reliable estimate of the mathematical uncertainty of the calculated dense displacement map.