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2020 | OriginalPaper | Buchkapitel

6. Isolation and Characterization of Triterpenoid and Steroidal Saponins

verfasst von : Mostafa Abdelrahman, Sudisha Jogaiah

Erschienen in: Bioactive Molecules in Plant Defense

Verlag: Springer International Publishing

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Abstract

Saponins are broadly dispersed natural products in the plant kingdom with massive structural and functional diversity, and therefore being regarded as an active components in medicinal plants. Saponin compounds have a significant roles in pharmaceutical industry, however the specific roles of saponins in plant defense as well as other biological process are remain underexplored. Saponins are glycosides of steroids, triterpenes or alkaloids, which are primarily found in roots and shoots of different plant species. Therefore, saponin compounds can be classified into steroidal, triterpenoidal or alkaloidal saponin depending on the nature of their aglycone structure. In this chapter, we will discussed the two major saponin classes, including triterpene saponins and steroidal saponins and their biological activities in pharmaceutical industries and plant-microbe interactions. In addition, saponin biosynthesis pathway and methods of induction of saponin contents will be also covered in this chapter.

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Literatur
Zurück zum Zitat Abdelrahman M, Sho H, Ito S-I, Yamauchi N, Shigyo M (2014) Compartmentation and localization of bioactive metabolites in different organs of Allium roylei. Biosci Biotechnol Biochem 78:1112–1122PubMedCrossRef Abdelrahman M, Sho H, Ito S-I, Yamauchi N, Shigyo M (2014) Compartmentation and localization of bioactive metabolites in different organs of Allium roylei. Biosci Biotechnol Biochem 78:1112–1122PubMedCrossRef
Zurück zum Zitat Abdelrahman M, Abdel-Motaal F, El-Sayed M, Jogaiah S, Shigyo M, Ito S-I, Tran LP (2016) Dissection of Trichoderma longibrachiatum-induced defense in onion (Allium cepa L.) against Fusarium oxysporum f. sp. cepa by target metabolite profiling. Plant Sci 246:128–138 Abdelrahman M, Abdel-Motaal F, El-Sayed M, Jogaiah S, Shigyo M, Ito S-I, Tran LP (2016) Dissection of Trichoderma longibrachiatum-induced defense in onion (Allium cepa L.) against Fusarium oxysporum f. sp. cepa by target metabolite profiling. Plant Sci 246:128–138
Zurück zum Zitat Abdelrahman M et al (2017a) RNA-sequencing-based transcriptome and biochemical analyses of steroidal saponin pathway in a complete set of Allium fistulosum—A. cepa monosomic addition lines. PLoS One 12:e0181784PubMedPubMedCentralCrossRef Abdelrahman M et al (2017a) RNA-sequencing-based transcriptome and biochemical analyses of steroidal saponin pathway in a complete set of Allium fistulosumA. cepa monosomic addition lines. PLoS One 12:e0181784PubMedPubMedCentralCrossRef
Zurück zum Zitat Abdelrahman M, Mahmoud HYAH, El-Sayed M, Tanaka S, Tran LP (2017b) Isolation and characterization of Cepa2, a natural alliospiroside A, from shallot (Allium cepa L. Aggregatum group) with anticancer activity. Plant Physiol Biochem 116:167–173PubMedCrossRef Abdelrahman M, Mahmoud HYAH, El-Sayed M, Tanaka S, Tran LP (2017b) Isolation and characterization of Cepa2, a natural alliospiroside A, from shallot (Allium cepa L. Aggregatum group) with anticancer activity. Plant Physiol Biochem 116:167–173PubMedCrossRef
Zurück zum Zitat Abed El Aziz MM, Ashou RAS, Melad AG (2019) A review on saponins from medicinal plants: chemistry, isolation, and determination. J Nanomed Res 7:282–288CrossRef Abed El Aziz MM, Ashou RAS, Melad AG (2019) A review on saponins from medicinal plants: chemistry, isolation, and determination. J Nanomed Res 7:282–288CrossRef
Zurück zum Zitat Abugabr Elhag HEE, Naila A, Ajit A, Abdul Aziz B, Sulaiman AZ (2018) Sequential extraction of saponins from Eurycoma longifolia roots by water extraction and ultrasound-assisted extraction. Mater Today Proc 5:21672–21681CrossRef Abugabr Elhag HEE, Naila A, Ajit A, Abdul Aziz B, Sulaiman AZ (2018) Sequential extraction of saponins from Eurycoma longifolia roots by water extraction and ultrasound-assisted extraction. Mater Today Proc 5:21672–21681CrossRef
Zurück zum Zitat Adel MM, Sehnal F, Jurzysta M (2000) Effects of alfalfa saponins on the moth Spodoptera littoralis. J Chem Ecol 26:1065–1078CrossRef Adel MM, Sehnal F, Jurzysta M (2000) Effects of alfalfa saponins on the moth Spodoptera littoralis. J Chem Ecol 26:1065–1078CrossRef
Zurück zum Zitat Allam NG, Abou-Taleb HK, Aboobia MM (2017) Antimicrobial and pesticidal activities of soya saponin. J Basic Environ Sci 4:262–267 Allam NG, Abou-Taleb HK, Aboobia MM (2017) Antimicrobial and pesticidal activities of soya saponin. J Basic Environ Sci 4:262–267
Zurück zum Zitat Amin HA, Hassan YM, Yehia SM (2013) Biotransformation of soybean saponin to soyasapogenol B by Aspergillus parasiticus. Egypt Pharm J 12:40–45 Amin HA, Hassan YM, Yehia SM (2013) Biotransformation of soybean saponin to soyasapogenol B by Aspergillus parasiticus. Egypt Pharm J 12:40–45
Zurück zum Zitat Bialy Z, Jurzysta M, Oleszek W, Piacente S, Pizza C (1999) Saponins in alfalfa (Medicago sativa L.) root and their structural elucidation. J Agric Food Chem 47:3185–3192PubMedCrossRef Bialy Z, Jurzysta M, Oleszek W, Piacente S, Pizza C (1999) Saponins in alfalfa (Medicago sativa L.) root and their structural elucidation. J Agric Food Chem 47:3185–3192PubMedCrossRef
Zurück zum Zitat Challinor VL, De Voss JJ (2013) Open-chain steroidal glycosides, a diverse class of plant saponins. Nat Prod Rep 30:429–454PubMedCrossRef Challinor VL, De Voss JJ (2013) Open-chain steroidal glycosides, a diverse class of plant saponins. Nat Prod Rep 30:429–454PubMedCrossRef
Zurück zum Zitat Challinor VL, Parsons PG, Chap S, White EF, Blanchfield JT, Lehmann RP, De Voss JJ (2012) Steroidal saponins from the roots of Smilax sp.: structure and bioactivity. Steroids 77:504–511PubMedCrossRef Challinor VL, Parsons PG, Chap S, White EF, Blanchfield JT, Lehmann RP, De Voss JJ (2012) Steroidal saponins from the roots of Smilax sp.: structure and bioactivity. Steroids 77:504–511PubMedCrossRef
Zurück zum Zitat Chen JH, Wu HY, Liau BC, Chang CMJ, Jong TT, Wu LC (2010) Identification and evaluation of antioxidants defatted Camellia oleifera seeds by isopropanol salting-out pretreatment. Food Chem 121:1246–1254CrossRef Chen JH, Wu HY, Liau BC, Chang CMJ, Jong TT, Wu LC (2010) Identification and evaluation of antioxidants defatted Camellia oleifera seeds by isopropanol salting-out pretreatment. Food Chem 121:1246–1254CrossRef
Zurück zum Zitat Cui C, Zong J, Sun Y, Zhang L, Ho C-T, Wan X, Hou R (2018) Triterpenoid saponins from the genus Camellia: structures, biological activities, and molecular simulation for structure–activity relationship. Food Funct 9:3069–3091PubMedCrossRef Cui C, Zong J, Sun Y, Zhang L, Ho C-T, Wan X, Hou R (2018) Triterpenoid saponins from the genus Camellia: structures, biological activities, and molecular simulation for structure–activity relationship. Food Funct 9:3069–3091PubMedCrossRef
Zurück zum Zitat Da Silva P, Eyraud V, Carre-Pierrat M, Sivignon C, Rahioui I, Royer C et al (2012) High toxicity and specificity of the saponin 3-GlcA-28-AraRhaxyl-medicagenate, from Medicago truncatula seeds, for Sitophilus oryzae. BMC Chem Biol 12:3PubMedPubMedCentralCrossRef Da Silva P, Eyraud V, Carre-Pierrat M, Sivignon C, Rahioui I, Royer C et al (2012) High toxicity and specificity of the saponin 3-GlcA-28-AraRhaxyl-medicagenate, from Medicago truncatula seeds, for Sitophilus oryzae. BMC Chem Biol 12:3PubMedPubMedCentralCrossRef
Zurück zum Zitat Fanani MZ, Fukushima EO, Sawai S, Tang J, Ishimori M, Sudo H, Ohyama K, Seki H, Saito K, Muranaka T (2019) Molecular basis of C-30 product regioselectivity of legume oxidases involved in high-value triterpenoid biosynthesis. Front Plant Sci 10:1520PubMedPubMedCentralCrossRef Fanani MZ, Fukushima EO, Sawai S, Tang J, Ishimori M, Sudo H, Ohyama K, Seki H, Saito K, Muranaka T (2019) Molecular basis of C-30 product regioselectivity of legume oxidases involved in high-value triterpenoid biosynthesis. Front Plant Sci 10:1520PubMedPubMedCentralCrossRef
Zurück zum Zitat Fattorusso E, Lanzotti V, Taglialatela-Scafati O, Di Rosa M, Ianaro A (2000) Cytotoxic saponins from bulbs of Allium porrum L. J Agric Food Chem 48:3455–3462PubMedCrossRef Fattorusso E, Lanzotti V, Taglialatela-Scafati O, Di Rosa M, Ianaro A (2000) Cytotoxic saponins from bulbs of Allium porrum L. J Agric Food Chem 48:3455–3462PubMedCrossRef
Zurück zum Zitat Fattorusso E, Iorizzi M, Lanzotti V (2002) Chemical composition of shallot (Allium ascalonicum Hort.). J Agric Food Chem 50:5686–5690PubMedCrossRef Fattorusso E, Iorizzi M, Lanzotti V (2002) Chemical composition of shallot (Allium ascalonicum Hort.). J Agric Food Chem 50:5686–5690PubMedCrossRef
Zurück zum Zitat Fu HZ, Wan KH, Yan QW, Zhou GP, Feng TT, Dai M, Zhong RJ (2017) Cytotoxic triterpenoid saponins from the defatted seeds of Camellia oleifera Abel. J Asian Nat Prod Res 20:412–422PubMedCrossRef Fu HZ, Wan KH, Yan QW, Zhou GP, Feng TT, Dai M, Zhong RJ (2017) Cytotoxic triterpenoid saponins from the defatted seeds of Camellia oleifera Abel. J Asian Nat Prod Res 20:412–422PubMedCrossRef
Zurück zum Zitat Fujimoto K, Nakamura S, Nakashima S, Matsumoto T, Uno K, Ohta T, Miura T, Matsuda H, Yoshikawa M (2012) Medicinal flowers. XXXV. Nor-oleanane-type and acylated oleanane-type triterpene saponins from the flower buds of Chinese Camellia japonica and their inhibitory effects on melanogenesis. Chem Pharm Bull 60:1188–1194 Fujimoto K, Nakamura S, Nakashima S, Matsumoto T, Uno K, Ohta T, Miura T, Matsuda H, Yoshikawa M (2012) Medicinal flowers. XXXV. Nor-oleanane-type and acylated oleanane-type triterpene saponins from the flower buds of Chinese Camellia japonica and their inhibitory effects on melanogenesis. Chem Pharm Bull 60:1188–1194
Zurück zum Zitat Geisler K, Hughes RK, Sainsbury F, Lomonossoff GP, Rejzek M, Fairhurst S et al (2013) Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants. Proc Natl Acad Sci USA 110:35CrossRef Geisler K, Hughes RK, Sainsbury F, Lomonossoff GP, Rejzek M, Fairhurst S et al (2013) Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants. Proc Natl Acad Sci USA 110:35CrossRef
Zurück zum Zitat Goławska S, Łukasik I, Wójcicka A, Sytykiewicz H (2012) Relationship between saponin content in alfalfa and aphid development. Acta Biol Crac Ser Bot 54:39–46 Goławska S, Łukasik I, Wójcicka A, Sytykiewicz H (2012) Relationship between saponin content in alfalfa and aphid development. Acta Biol Crac Ser Bot 54:39–46
Zurück zum Zitat Guo N, Tong T, Ren N, Tu Y, Li B (2018) Saponins from seeds of genus Camellia: Phytochemistry and bioactivity. Phytochemistry 149:42–55PubMedCrossRef Guo N, Tong T, Ren N, Tu Y, Li B (2018) Saponins from seeds of genus Camellia: Phytochemistry and bioactivity. Phytochemistry 149:42–55PubMedCrossRef
Zurück zum Zitat Huang Q, Shao L, He M, Chen H, Liu D, Luo Y, Dai Y (2005) Inhibitory effects of sasanquasaponin on over-expression of ICAM-1 and on enhancement of capillary permeability induced by burns in rats. Burns 31:637–642PubMedCrossRef Huang Q, Shao L, He M, Chen H, Liu D, Luo Y, Dai Y (2005) Inhibitory effects of sasanquasaponin on over-expression of ICAM-1 and on enhancement of capillary permeability induced by burns in rats. Burns 31:637–642PubMedCrossRef
Zurück zum Zitat Huhman DV, Berhow MA, Sumner LW (2005) Quantification of saponins in aerial and subterranean tissues of Medicago truncatula. J Agric Food Chem 53:1914–1920PubMedCrossRef Huhman DV, Berhow MA, Sumner LW (2005) Quantification of saponins in aerial and subterranean tissues of Medicago truncatula. J Agric Food Chem 53:1914–1920PubMedCrossRef
Zurück zum Zitat Ikeda T, Tsumagari H, Nohara T (2000) Steroidal oligoglycosides from the seeds of Allium tuberosum. Chem Pharm Bull 48(3):362–365 Ikeda T, Tsumagari H, Nohara T (2000) Steroidal oligoglycosides from the seeds of Allium tuberosum. Chem Pharm Bull 48(3):362–365
Zurück zum Zitat Jiang Y, Wang N-L, Yao X-S et al (1998) Structural elucidation of the anticoagulation and anticancer constituents from Allium chinense. Yao Xue Xue Bao 33:355–361PubMed Jiang Y, Wang N-L, Yao X-S et al (1998) Structural elucidation of the anticoagulation and anticancer constituents from Allium chinense. Yao Xue Xue Bao 33:355–361PubMed
Zurück zum Zitat Joshi R, Sood S, Dogra P, Mahendru M, Kumar D, Bhangalia S, Pal HC, Kumar N, Bhushan S, Gulati A (2013) In vitro cytotoxicity, antimicrobial, and metal-chelating activity of triterpene saponins from tea seed grown in Kangra valley, India. Med Chem Res 22:4030–4038CrossRef Joshi R, Sood S, Dogra P, Mahendru M, Kumar D, Bhangalia S, Pal HC, Kumar N, Bhushan S, Gulati A (2013) In vitro cytotoxicity, antimicrobial, and metal-chelating activity of triterpene saponins from tea seed grown in Kangra valley, India. Med Chem Res 22:4030–4038CrossRef
Zurück zum Zitat Kapusta I, Janda B, Stochmal A, Oleszek W (2005a) Determination of saponins in aerial parts of barrel medic (Medicago truncatula) by liquid chromatography-electrospray ionization/mass spectrometry. J Agric Food Chem 53:7654–7660PubMedCrossRef Kapusta I, Janda B, Stochmal A, Oleszek W (2005a) Determination of saponins in aerial parts of barrel medic (Medicago truncatula) by liquid chromatography-electrospray ionization/mass spectrometry. J Agric Food Chem 53:7654–7660PubMedCrossRef
Zurück zum Zitat Kapusta I, Stochmal A, Perrone A, Piacente S, Pizza C, Oleszek W (2005b) Triterpene saponins from barrel medic (Medicago truncatula) aerial parts. J Agric Food Chem 53:2164–2170PubMedCrossRef Kapusta I, Stochmal A, Perrone A, Piacente S, Pizza C, Oleszek W (2005b) Triterpene saponins from barrel medic (Medicago truncatula) aerial parts. J Agric Food Chem 53:2164–2170PubMedCrossRef
Zurück zum Zitat Kawashima K, Mimaki Y, Sashida Y (1991) Steroidal saponins from Allium giganteum and A. aflatunense. Phytochemistry 30:3063–3067CrossRef Kawashima K, Mimaki Y, Sashida Y (1991) Steroidal saponins from Allium giganteum and A. aflatunense. Phytochemistry 30:3063–3067CrossRef
Zurück zum Zitat Khan MI, Ahhmed A, Shin JH, Baek JS, Kim MY, Kim JD (2018) Green tea seed isolated saponins exerts antibacterial effects against various strains of gram positive and gram negative bacteria, a comprehensive study in vitro and in vivo. Evid Based Complement Alternat Med 2018:3486106PubMedPubMedCentralCrossRef Khan MI, Ahhmed A, Shin JH, Baek JS, Kim MY, Kim JD (2018) Green tea seed isolated saponins exerts antibacterial effects against various strains of gram positive and gram negative bacteria, a comprehensive study in vitro and in vivo. Evid Based Complement Alternat Med 2018:3486106PubMedPubMedCentralCrossRef
Zurück zum Zitat Kräutler B, Sahu NP, Banerjee S, Mondal NB, Mandal D (2008) Steroidal saponin. In: Kinghorn AD, Columbus OH, Falk H, Kobayashi LJ (eds) Fortschritte der chemie organischer naturstoffe/progress in the chemistry of organic natural products. Springer, Vienna, pp 45–141 Kräutler B, Sahu NP, Banerjee S, Mondal NB, Mandal D (2008) Steroidal saponin. In: Kinghorn AD, Columbus OH, Falk H, Kobayashi LJ (eds) Fortschritte der chemie organischer naturstoffe/progress in the chemistry of organic natural products. Springer, Vienna, pp 45–141
Zurück zum Zitat Kravets SD, Vollerner YS, Gorovits MB et al (1986a) Steroids of the spirostan and furostan series from plants of the genus Allium XXI. Structure of alliospiroside A and alliofuroside A from Allium cepa. Chem Nat Comp 22:174–181CrossRef Kravets SD, Vollerner YS, Gorovits MB et al (1986a) Steroids of the spirostan and furostan series from plants of the genus Allium XXI. Structure of alliospiroside A and alliofuroside A from Allium cepa. Chem Nat Comp 22:174–181CrossRef
Zurück zum Zitat Kravets SD, Vollerner YS, Gorovits MB et al (1986b) Steroids of the spirostan and furostan series from plants of the genus Allium XXII. The structure of alliospiroside B from Allium cepa. Chem Nat Comp 22:553–556CrossRef Kravets SD, Vollerner YS, Gorovits MB et al (1986b) Steroids of the spirostan and furostan series from plants of the genus Allium XXII. The structure of alliospiroside B from Allium cepa. Chem Nat Comp 22:553–556CrossRef
Zurück zum Zitat Kuo PC, Lin TC, Yang CW, Lin CL, Chen GF, Huang JW (2010) Bioactive saponin from tea seed pomace with inhibitory effects against Rhizoctonia solani. J Agric Food Chem 58:8618–8622PubMedCrossRef Kuo PC, Lin TC, Yang CW, Lin CL, Chen GF, Huang JW (2010) Bioactive saponin from tea seed pomace with inhibitory effects against Rhizoctonia solani. J Agric Food Chem 58:8618–8622PubMedCrossRef
Zurück zum Zitat Lanzotti V (2005) Bioactive saponins from Allium and Aster plants. Phytochem Rev 4:95–110CrossRef Lanzotti V (2005) Bioactive saponins from Allium and Aster plants. Phytochem Rev 4:95–110CrossRef
Zurück zum Zitat Lei Z, Watson BS, Huhman D, Yang DS, Sumner LW (2019) Large-scale profiling of saponins in different ecotypes of Medicago truncatula. Front Plant Sci 10:850PubMedPubMedCentralCrossRef Lei Z, Watson BS, Huhman D, Yang DS, Sumner LW (2019) Large-scale profiling of saponins in different ecotypes of Medicago truncatula. Front Plant Sci 10:850PubMedPubMedCentralCrossRef
Zurück zum Zitat Li N, Li X, Feng Z (2008) Chemical constituents of tea seed saponins part from Camellia sinensis cultivated in China. J Shenyang Pharm Univ 25:544–548 Li N, Li X, Feng Z (2008) Chemical constituents of tea seed saponins part from Camellia sinensis cultivated in China. J Shenyang Pharm Univ 25:544–548
Zurück zum Zitat Li N, Ma Z-J, Chu Y, Wang Y, Li X (2013) Phytochemical analysis of the triterpenoids with cytotoxicity and QR inducing properties from the total tea seed saponin of Camellia sinensis. Fitoterapia 84:321–325PubMedCrossRef Li N, Ma Z-J, Chu Y, Wang Y, Li X (2013) Phytochemical analysis of the triterpenoids with cytotoxicity and QR inducing properties from the total tea seed saponin of Camellia sinensis. Fitoterapia 84:321–325PubMedCrossRef
Zurück zum Zitat Li X, Zhao J, Peng C, Chen Z, Liu Y, Xu Q, Khan IA, Yang S (2014) Cytotoxic triterpenoid glycosides from the roots of Camellia oleifera. Planta Med 80:590–598PubMedCrossRef Li X, Zhao J, Peng C, Chen Z, Liu Y, Xu Q, Khan IA, Yang S (2014) Cytotoxic triterpenoid glycosides from the roots of Camellia oleifera. Planta Med 80:590–598PubMedCrossRef
Zurück zum Zitat Li X, Zhao J, Li X, LiuY XQ, Khan IA, Yang S (2015) New triterpenoid glycosides from the roots of Camellia oleifera Abel. Helv Chim Acta 98:496–508CrossRef Li X, Zhao J, Li X, LiuY XQ, Khan IA, Yang S (2015) New triterpenoid glycosides from the roots of Camellia oleifera Abel. Helv Chim Acta 98:496–508CrossRef
Zurück zum Zitat Lu Y, Umeda T, Yagi A, Sakata K, Chaudhuri T, Ganguly DK, Sarma S (2000) Triterpenoid saponins from the roots of tea plant (Camellia sinensis var. assamica). Phytochemistry 53:941–946PubMedCrossRef Lu Y, Umeda T, Yagi A, Sakata K, Chaudhuri T, Ganguly DK, Sarma S (2000) Triterpenoid saponins from the roots of tea plant (Camellia sinensis var. assamica). Phytochemistry 53:941–946PubMedCrossRef
Zurück zum Zitat Martyniuk S, Biały Z (2008) Effects of saponins from Medicago arabica on in vitro growth of Cephalosporium gramineum. Phytopathol Pol 49:49–55 Martyniuk S, Biały Z (2008) Effects of saponins from Medicago arabica on in vitro growth of Cephalosporium gramineum. Phytopathol Pol 49:49–55
Zurück zum Zitat Matsuda H, Nakamura S, Fujimoto K, Moriuchi R, Kimura Y, Ikoma N, Hata Y, Muraoka O, Yoshikawa M (2010) Medicinal Flowers. XXXI. Acylated oleanane-type triterpene saponins, Sasanquasaponins I-V, with antiallergic activity from the flower buds of Camellia sasanqua. Chem Pharm Bull 58:1617–1621CrossRef Matsuda H, Nakamura S, Fujimoto K, Moriuchi R, Kimura Y, Ikoma N, Hata Y, Muraoka O, Yoshikawa M (2010) Medicinal Flowers. XXXI. Acylated oleanane-type triterpene saponins, Sasanquasaponins I-V, with antiallergic activity from the flower buds of Camellia sasanqua. Chem Pharm Bull 58:1617–1621CrossRef
Zurück zum Zitat Matsuda H, Hamao M, Nakamura S, Kon’i H, Murata M, Yoshikawa M (2012) Medicinal flowers. XXXIII. Anti-hyperlipidemic and anti-hyperglycemic effects of chakasaponins I-III and structure of chakasaponin IV from flower buds of Chinese tea plant (Camellia sinensis). Chem Pharm Bull 60:674–680 Matsuda H, Hamao M, Nakamura S, Kon’i H, Murata M, Yoshikawa M (2012) Medicinal flowers. XXXIII. Anti-hyperlipidemic and anti-hyperglycemic effects of chakasaponins I-III and structure of chakasaponin IV from flower buds of Chinese tea plant (Camellia sinensis). Chem Pharm Bull 60:674–680
Zurück zum Zitat Morikawa T, Li N, Nagatomo A, Matsuda H, Li X, Yoshikawa M (2006) Triterpene saponins with gastroprotective effects from tea seed (the seeds of Camellia sinensis). J Nat Prod 69:185–190PubMedCrossRef Morikawa T, Li N, Nagatomo A, Matsuda H, Li X, Yoshikawa M (2006) Triterpene saponins with gastroprotective effects from tea seed (the seeds of Camellia sinensis). J Nat Prod 69:185–190PubMedCrossRef
Zurück zum Zitat Morikawa T, Nakamura S, Kato Y, Muraoka O, Matsuda H, Yoshikawa M (2007) Bioactive saponins and glycosides. XXVIII. new triterpene saponins, foliatheasaponins I, II, III, IV, and V, from tencha (the leaves of Camellia sinensis). Chem Pharm Bull 55:293–298 Morikawa T, Nakamura S, Kato Y, Muraoka O, Matsuda H, Yoshikawa M (2007) Bioactive saponins and glycosides. XXVIII. new triterpene saponins, foliatheasaponins I, II, III, IV, and V, from tencha (the leaves of Camellia sinensis). Chem Pharm Bull 55:293–298
Zurück zum Zitat Mostafa A et al (2013) Aginoside saponin, a potent antifungal compound, and secondary metabolite analyses from Allium nigrum L. Phytochem Lett 6:274–280CrossRef Mostafa A et al (2013) Aginoside saponin, a potent antifungal compound, and secondary metabolite analyses from Allium nigrum L. Phytochem Lett 6:274–280CrossRef
Zurück zum Zitat Mskhiladze L, Legault J, Lavoie S, Mshvildadze V, Kuchukhidze J, Elias R, Pichette A (2008) Cytotoxic steroidal saponins from the flowers of Allium leucanthum. Molecules 13:2925–2934PubMedPubMedCentralCrossRef Mskhiladze L, Legault J, Lavoie S, Mshvildadze V, Kuchukhidze J, Elias R, Pichette A (2008) Cytotoxic steroidal saponins from the flowers of Allium leucanthum. Molecules 13:2925–2934PubMedPubMedCentralCrossRef
Zurück zum Zitat Murakami T, Nakamura J, Matsuda H, Yoshikawa M (1999) Bioactive saponins and glycosides. XV. Saponin constituents with gastroprotective effect from the seeds of tea plant, Camellia sinensis L. var. assamica Pierre, cultivated in Sri Lanka: structures of assamsaponins A, B, C, D, and E. Chem Pharm Bull 47:1759–1764CrossRef Murakami T, Nakamura J, Matsuda H, Yoshikawa M (1999) Bioactive saponins and glycosides. XV. Saponin constituents with gastroprotective effect from the seeds of tea plant, Camellia sinensis L. var. assamica Pierre, cultivated in Sri Lanka: structures of assamsaponins A, B, C, D, and E. Chem Pharm Bull 47:1759–1764CrossRef
Zurück zum Zitat Murakami T, Nakamura J, Kageura T, Matsuda H, Yoshikawa M (2000) Bioactive saponins and glycosides. XVII. Inhibitory effect on gastric emptying and accelerating effect on gastrointestinal transit of tea saponins: structures of assamsaponins F, G, H, I, and J from the seeds and leaves of the tea plant. Chem Pharm Bull (Tokyo) 48:1720–1725CrossRef Murakami T, Nakamura J, Kageura T, Matsuda H, Yoshikawa M (2000) Bioactive saponins and glycosides. XVII. Inhibitory effect on gastric emptying and accelerating effect on gastrointestinal transit of tea saponins: structures of assamsaponins F, G, H, I, and J from the seeds and leaves of the tea plant. Chem Pharm Bull (Tokyo) 48:1720–1725CrossRef
Zurück zum Zitat Myose M, Warashina T, Miyase T (2012) Triterpene saponins with hyaluronidase inhibitory activity from the seeds of Camellia sinensis. Chem Pharm Bull 60:612–623CrossRef Myose M, Warashina T, Miyase T (2012) Triterpene saponins with hyaluronidase inhibitory activity from the seeds of Camellia sinensis. Chem Pharm Bull 60:612–623CrossRef
Zurück zum Zitat Nakamura S, Moriura T, Park S, Fujimoto K, Matsumoto T, Ohta T, Matsuda M, Yoshikawa H (2012) Melanogenesis inhibitory and fibroblast proliferation accelerating effects of noroleanane- and oleanane-type triterpene oligoglycosides from the flower buds of Camellia japonica (1). J Nat Prod 75:1425–1430PubMedCrossRef Nakamura S, Moriura T, Park S, Fujimoto K, Matsumoto T, Ohta T, Matsuda M, Yoshikawa H (2012) Melanogenesis inhibitory and fibroblast proliferation accelerating effects of noroleanane- and oleanane-type triterpene oligoglycosides from the flower buds of Camellia japonica (1). J Nat Prod 75:1425–1430PubMedCrossRef
Zurück zum Zitat Ohta T, Nakamura S, Nakashima S, Matsumoto T, Ogawa K, Fujimoto K, Fukaya M, Yoshikawa M, Matsuda H (2015) Acylated oleanane-type triterpene oligoglycosides from the flower buds of Camellia sinensis var. assamica. Tetrahedron 71:846–851CrossRef Ohta T, Nakamura S, Nakashima S, Matsumoto T, Ogawa K, Fujimoto K, Fukaya M, Yoshikawa M, Matsuda H (2015) Acylated oleanane-type triterpene oligoglycosides from the flower buds of Camellia sinensis var. assamica. Tetrahedron 71:846–851CrossRef
Zurück zum Zitat Peng J-P, Yao X-S, Tezuka Y et al (1996) Furostanol glycosides from bulbs of Allium chinense. Phytochemistry 41:283–285PubMedCrossRef Peng J-P, Yao X-S, Tezuka Y et al (1996) Furostanol glycosides from bulbs of Allium chinense. Phytochemistry 41:283–285PubMedCrossRef
Zurück zum Zitat Pérez AJ, Kowalczyk M, Simonet AM, Macias FA, Oleszek W, Stochmal A (2013) Isolation and structural determination of triterpenoid glycosides from the aerial parts of alsike clover (Trifolium hybridum L.). J Agric Food Chem 61:2631–2637PubMedCrossRef Pérez AJ, Kowalczyk M, Simonet AM, Macias FA, Oleszek W, Stochmal A (2013) Isolation and structural determination of triterpenoid glycosides from the aerial parts of alsike clover (Trifolium hybridum L.). J Agric Food Chem 61:2631–2637PubMedCrossRef
Zurück zum Zitat Pollier J, Morreel K, Geelen D, Goossens A (2011) Metabolite profiling of triterpene saponins in Medicago truncatula hairy roots by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. J Nat Prod 74:1462–1476PubMedCrossRef Pollier J, Morreel K, Geelen D, Goossens A (2011) Metabolite profiling of triterpene saponins in Medicago truncatula hairy roots by liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. J Nat Prod 74:1462–1476PubMedCrossRef
Zurück zum Zitat Sagesaka YM, Uemura T, Watanabe N, Sakata K, Uzawa J (1994) A new glucuronide saponin from tea leaves (Camellia sinensis var. sinensis.). Biosci Biotechnol Biochem 58:2036–2040PubMedCrossRef Sagesaka YM, Uemura T, Watanabe N, Sakata K, Uzawa J (1994) A new glucuronide saponin from tea leaves (Camellia sinensis var. sinensis.). Biosci Biotechnol Biochem 58:2036–2040PubMedCrossRef
Zurück zum Zitat Sang SM, Zou M, Xia Z et al (2001) New spirostanol saponins from Chinese chives (Allium tuberosum). J Agric Food Chem 49:4780–4783PubMedCrossRef Sang SM, Zou M, Xia Z et al (2001) New spirostanol saponins from Chinese chives (Allium tuberosum). J Agric Food Chem 49:4780–4783PubMedCrossRef
Zurück zum Zitat Sashida Y, Kawashima K, Mimaki Y (1991) Novel polyhydroxylated steroidal saponins from Allium giganteum. Chem Pharm Bull 39:698–703CrossRef Sashida Y, Kawashima K, Mimaki Y (1991) Novel polyhydroxylated steroidal saponins from Allium giganteum. Chem Pharm Bull 39:698–703CrossRef
Zurück zum Zitat Sparg SG, Light ME, van Staden J (2004) Biological activities and distribution of plant saponins. J Ethnopharmacol 94:219–243PubMedCrossRef Sparg SG, Light ME, van Staden J (2004) Biological activities and distribution of plant saponins. J Ethnopharmacol 94:219–243PubMedCrossRef
Zurück zum Zitat Sugimoto S, Chi G, Kato Y, Nakamura S, Matsuda H, Yoshikawa M (2009) Medicinal flowers. XXVI.1 structures of acylated oleanane-type triterpene oligoglycosides, yuchasaponins A, B, C, and D, from the flower buds of Camellia oleifera-gastroprotective, aldose reductase inhibitory, and radical scavenging effects. Chem Pharm Bull 57:269–275CrossRef Sugimoto S, Chi G, Kato Y, Nakamura S, Matsuda H, Yoshikawa M (2009) Medicinal flowers. XXVI.1 structures of acylated oleanane-type triterpene oligoglycosides, yuchasaponins A, B, C, and D, from the flower buds of Camellia oleifera-gastroprotective, aldose reductase inhibitory, and radical scavenging effects. Chem Pharm Bull 57:269–275CrossRef
Zurück zum Zitat Tava A, Pecetti L (2012) Chemical investigation of saponins from twelve annual Medicago species and their bioassay with the brine shrimp Artemia salina. Nat prod commun 7(7):837–840 Tava A, Pecetti L (2012) Chemical investigation of saponins from twelve annual Medicago species and their bioassay with the brine shrimp Artemia salina. Nat prod commun 7(7):837–840
Zurück zum Zitat Tava A, Mella M, Avato P, Argentieri MP, Bialy Z, Jurzysta M (2005) Triterpenoid glycosides from leaves of Medicago arborea L. J Agric Food Chem 53:9954–9965PubMedCrossRef Tava A, Mella M, Avato P, Argentieri MP, Bialy Z, Jurzysta M (2005) Triterpenoid glycosides from leaves of Medicago arborea L. J Agric Food Chem 53:9954–9965PubMedCrossRef
Zurück zum Zitat Teshima Y, Ikeda T, Imada K, Sasaki K, El-Sayed MA, Shigyo M, Tanaka S, S-I/ I (2013) Identification and biological activity of antifungal saponins from shallot (Allium cepa L. Aggregatum Group). J Agric Food Chem (31):7440–7445 Teshima Y, Ikeda T, Imada K, Sasaki K, El-Sayed MA, Shigyo M, Tanaka S, S-I/ I (2013) Identification and biological activity of antifungal saponins from shallot (Allium cepa L. Aggregatum Group). J Agric Food Chem (31):7440–7445
Zurück zum Zitat Trdá L, Janda M, Macková D, Pospíchalová R, Dobrev PI, Burketová L, Matušinsky P (2019) Dual Mode of the saponin aescin in plant protection: antifungal agent and plant defense elicitor. Front Plant Sci 10:1408CrossRef Trdá L, Janda M, Macková D, Pospíchalová R, Dobrev PI, Burketová L, Matušinsky P (2019) Dual Mode of the saponin aescin in plant protection: antifungal agent and plant defense elicitor. Front Plant Sci 10:1408CrossRef
Zurück zum Zitat Uddin NM, Sharma G, Yang J-L, Choi HS, Lim SI, Kang KW, Oh WK (2014) Oleanane triterpenes as protein tyrosine phosphatase 1B (PTP1B) inhibitors from Camellia japonica. Phytochemistry 103:99–106PubMedCrossRef Uddin NM, Sharma G, Yang J-L, Choi HS, Lim SI, Kang KW, Oh WK (2014) Oleanane triterpenes as protein tyrosine phosphatase 1B (PTP1B) inhibitors from Camellia japonica. Phytochemistry 103:99–106PubMedCrossRef
Zurück zum Zitat Varughese T, Manir MM, Rahaman M, Kim JK, Lee B-G, Moon S-S (2011) Tea triterpenoidal saponins from the roots of Camellia sinensis have inhibitory effects against alcohol dehydrogenase. Planta Med 77:2029–2036PubMedCrossRef Varughese T, Manir MM, Rahaman M, Kim JK, Lee B-G, Moon S-S (2011) Tea triterpenoidal saponins from the roots of Camellia sinensis have inhibitory effects against alcohol dehydrogenase. Planta Med 77:2029–2036PubMedCrossRef
Zurück zum Zitat Vincken J-P, Heng L, Groot A, Gruppen H (2007) Saponins, classification and occurrence in the plant kingdom. Phytochemistry 68:275–297PubMedCrossRef Vincken J-P, Heng L, Groot A, Gruppen H (2007) Saponins, classification and occurrence in the plant kingdom. Phytochemistry 68:275–297PubMedCrossRef
Zurück zum Zitat Vo NN, Fukushima EO, Muranaka T (2017) Structure and hemolytic activity relationships of triterpenoid saponins and sapogenins. J Nat Med 71(1) Vo NN, Fukushima EO, Muranaka T (2017) Structure and hemolytic activity relationships of triterpenoid saponins and sapogenins. J Nat Med 71(1)
Zurück zum Zitat Vollerner YS, Abdullaev ND, Gorovits MB et al (1984) Steroid saponins and sapogenins of Allium XX. Structure of karataviosides E and F. Chem Nat Comp 20:64–68CrossRef Vollerner YS, Abdullaev ND, Gorovits MB et al (1984) Steroid saponins and sapogenins of Allium XX. Structure of karataviosides E and F. Chem Nat Comp 20:64–68CrossRef
Zurück zum Zitat Vollerner YS, Kravets SD, Shaskov AS et al (1989) Steroids of the spirostan and furostan series from plants of the genus Allium XXVI. Structure of anzurogenin and anzuroside from the collective fruits of Allium suvorovii and Allium stipitatum. Chem Nat Comp 25:431–435CrossRef Vollerner YS, Kravets SD, Shaskov AS et al (1989) Steroids of the spirostan and furostan series from plants of the genus Allium XXVI. Structure of anzurogenin and anzuroside from the collective fruits of Allium suvorovii and Allium stipitatum. Chem Nat Comp 25:431–435CrossRef
Zurück zum Zitat Wu J, Zhao J, Liu Y, Li X, Xu Q, Feng Y, Khan IA, Yang S (2015) Five new triterpenoid saponins from the roots of Camellia oleifera C. Abel with cytotoxic activities. Phytochem Lett 13:379–385CrossRef Wu J, Zhao J, Liu Y, Li X, Xu Q, Feng Y, Khan IA, Yang S (2015) Five new triterpenoid saponins from the roots of Camellia oleifera C. Abel with cytotoxic activities. Phytochem Lett 13:379–385CrossRef
Zurück zum Zitat Wu JP, Kang NX, Zhang MY, Gao HW, Li XR, Liu YL et al (2018) Oleiferoside W from the roots of Camellia oleifera C. Abel, inducing cell cycle arrest and apoptosis in A549 cells. J Asian Nat Prod Res 20:793–806 Wu JP, Kang NX, Zhang MY, Gao HW, Li XR, Liu YL et al (2018) Oleiferoside W from the roots of Camellia oleifera C. Abel, inducing cell cycle arrest and apoptosis in A549 cells. J Asian Nat Prod Res 20:793–806
Zurück zum Zitat Yang C-R, Zhang Y, Jacob MR, Khan S, Zhang YJ, Li X-C (2006) Antifungal activity of C-27 steroidal saponins. Antimicrob Agents Chemother 50:1710–1714PubMedPubMedCentralCrossRef Yang C-R, Zhang Y, Jacob MR, Khan S, Zhang YJ, Li X-C (2006) Antifungal activity of C-27 steroidal saponins. Antimicrob Agents Chemother 50:1710–1714PubMedPubMedCentralCrossRef
Zurück zum Zitat Yang WS, Ko J, Kim E, Kim JH, Park JG, Sung NY, Kim HG, Yang S, Rho HS, Hong YD, Shin SS, Cho JY (2014) 21-O-Angeloyltheasapogenol E3, a novel triterpenoid saponin from the seeds of tea plants, inhibits macrophage-mediated inflammatory responses in a NF-κB-dependent manner. Media Inflamm:1–9 Yang WS, Ko J, Kim E, Kim JH, Park JG, Sung NY, Kim HG, Yang S, Rho HS, Hong YD, Shin SS, Cho JY (2014) 21-O-Angeloyltheasapogenol E3, a novel triterpenoid saponin from the seeds of tea plants, inhibits macrophage-mediated inflammatory responses in a NF-κB-dependent manner. Media Inflamm:1–9
Zurück zum Zitat Yang P, Li X, Liu YL, Xu QM, Li YQ, Yang SL (2015) Two triterpenoid glycosides from the roots of Camellia oleifera and their cytotoxic activity. J Asian Nat Prod Res 17:800–807 Yang P, Li X, Liu YL, Xu QM, Li YQ, Yang SL (2015) Two triterpenoid glycosides from the roots of Camellia oleifera and their cytotoxic activity. J Asian Nat Prod Res 17:800–807
Zurück zum Zitat Yoshikawa M, Harada E, Murakami T, Matsuda H, Yamahara J, Murakami N (1994) Camelliasaponins B1, B2, C1 and C2, new type inhibitors of ethanol absorption in rats from the seeds of Camellia japonica L. Chem Pharm Bull 42:742–744CrossRef Yoshikawa M, Harada E, Murakami T, Matsuda H, Yamahara J, Murakami N (1994) Camelliasaponins B1, B2, C1 and C2, new type inhibitors of ethanol absorption in rats from the seeds of Camellia japonica L. Chem Pharm Bull 42:742–744CrossRef
Zurück zum Zitat Yoshikawa M, Murakami T, Yoshizumi S, Murakami N, Yamahara J, Matsuda H (1996) Bioactive saponins and glycosides. V. acylated polyhydroxyolean-12-ene triterpene oligoglycosides, camelliasaponins A1, A2, B1, B2, C1 and C2, from the seeds of Camellia japonica L.: structures and inhibitory activity on alcohol absorption. Chem Pharm Bull 44:1899–1907CrossRef Yoshikawa M, Murakami T, Yoshizumi S, Murakami N, Yamahara J, Matsuda H (1996) Bioactive saponins and glycosides. V. acylated polyhydroxyolean-12-ene triterpene oligoglycosides, camelliasaponins A1, A2, B1, B2, C1 and C2, from the seeds of Camellia japonica L.: structures and inhibitory activity on alcohol absorption. Chem Pharm Bull 44:1899–1907CrossRef
Zurück zum Zitat Yoshikawa M, Morikawa T, Li N, Nagatomo A, Li X, Matsuda H (2005) Bioactive saponins and glycosides. XXIII. Triterpene saponins with gastroprotective effect from the seeds of Camellia sinensis-theasaponins E3, E4, E5, E6, and E7. Chem Pharm Bull 53:1559–1564CrossRef Yoshikawa M, Morikawa T, Li N, Nagatomo A, Li X, Matsuda H (2005) Bioactive saponins and glycosides. XXIII. Triterpene saponins with gastroprotective effect from the seeds of Camellia sinensis-theasaponins E3, E4, E5, E6, and E7. Chem Pharm Bull 53:1559–1564CrossRef
Zurück zum Zitat Yoshikawa M, Morikawa T, Nakamura S, Li N, Li X, Matsuda H (2007) Bioactive saponins and glycosides. XXV. Acylated oleanane-type triterpene saponins from the seeds of tea plant (Camellia sinensis). Chem Pharm Bull 55:57–63CrossRef Yoshikawa M, Morikawa T, Nakamura S, Li N, Li X, Matsuda H (2007) Bioactive saponins and glycosides. XXV. Acylated oleanane-type triterpene saponins from the seeds of tea plant (Camellia sinensis). Chem Pharm Bull 55:57–63CrossRef
Zurück zum Zitat Yoshikawa M, Sugimoto S, Nakamura S, Matsuda H (2008) Medicinal flowers. XXII. Structures of chakasaponins V and VI, chakanoside I, and chakaflavonoside A from flower buds of Chinese tea plant (Camellia sinensis). Chem Pharm Bull 56:1297–1303CrossRef Yoshikawa M, Sugimoto S, Nakamura S, Matsuda H (2008) Medicinal flowers. XXII. Structures of chakasaponins V and VI, chakanoside I, and chakaflavonoside A from flower buds of Chinese tea plant (Camellia sinensis). Chem Pharm Bull 56:1297–1303CrossRef
Zurück zum Zitat Yu X-L, He Y (2018) Optimization of tea-leaf saponins water extraction and relationships between their contents and tea (Camellia sinensis) tree varieties. Food Sci Nutr 6:1734–1740PubMedPubMedCentralCrossRef Yu X-L, He Y (2018) Optimization of tea-leaf saponins water extraction and relationships between their contents and tea (Camellia sinensis) tree varieties. Food Sci Nutr 6:1734–1740PubMedPubMedCentralCrossRef
Zurück zum Zitat Yu Z, Zhang T, Zhou F, Xiao X, Ding X, He H, Rang J, Quan M, Wang T, Zuo M, Xia L (2015) Anticancer activity of saponins from Allium chinense against the B16 melanoma and 4T1 breast carcinoma cell. Evid Based Complement Altern Med 2015:Article ID 725023 Yu Z, Zhang T, Zhou F, Xiao X, Ding X, He H, Rang J, Quan M, Wang T, Zuo M, Xia L (2015) Anticancer activity of saponins from Allium chinense against the B16 melanoma and 4T1 breast carcinoma cell. Evid Based Complement Altern Med 2015:Article ID 725023
Zurück zum Zitat Yuan L, Ji TF, Li CJ et al (2009) Two new steroidal saponins from the seeds of Allium cepa L. J Asian Nat Prod Res 11:213–218PubMedCrossRef Yuan L, Ji TF, Li CJ et al (2009) Two new steroidal saponins from the seeds of Allium cepa L. J Asian Nat Prod Res 11:213–218PubMedCrossRef
Zurück zum Zitat Zhang XF, Han Y-Y, Bao G-H, Ling T-J, Zhang L, Gao L-P, Xia T (2012) A new saponin from tea seed pomace (Camellia oleifera Abel) and its protective effect on PC12 cells. Molecules 17:11721–11728PubMedPubMedCentralCrossRef Zhang XF, Han Y-Y, Bao G-H, Ling T-J, Zhang L, Gao L-P, Xia T (2012) A new saponin from tea seed pomace (Camellia oleifera Abel) and its protective effect on PC12 cells. Molecules 17:11721–11728PubMedPubMedCentralCrossRef
Zurück zum Zitat Zhang H, Zhang W, Jiang J, Du J, Yang F (2015) Comparison of purification methods and component identification of tea saponin. China Oils Fats 40:94–98 Zhang H, Zhang W, Jiang J, Du J, Yang F (2015) Comparison of purification methods and component identification of tea saponin. China Oils Fats 40:94–98
Zurück zum Zitat Zhang ZY, Wu JP, Gao BB, Ren HT, Liu YL, Li XR et al (2016) Two new 28-nor-oleanane-type triterpene saponins from roots of Camellia oleifera and their cytotoxic activity. J Asian Nat Prod Res 18:669–676 Zhang ZY, Wu JP, Gao BB, Ren HT, Liu YL, Li XR et al (2016) Two new 28-nor-oleanane-type triterpene saponins from roots of Camellia oleifera and their cytotoxic activity. J Asian Nat Prod Res 18:669–676
Zurück zum Zitat Zhou H, Wang CZ, Ye JZ, Chen HX (2014) New triterpene saponins from the seed cake of Camellia Oleifera and their cytotoxic activity. Phytochem Lett 8:46–51CrossRef Zhou H, Wang CZ, Ye JZ, Chen HX (2014) New triterpene saponins from the seed cake of Camellia Oleifera and their cytotoxic activity. Phytochem Lett 8:46–51CrossRef
Zurück zum Zitat Zong JF, Wang R (2015) Novel triterpenoid saponins from residual seed cake of Camellia oleifera Abel. show anti-proliferative activity against tumor cells. Fitoterapia 107:7–13CrossRef Zong JF, Wang R (2015) Novel triterpenoid saponins from residual seed cake of Camellia oleifera Abel. show anti-proliferative activity against tumor cells. Fitoterapia 107:7–13CrossRef
Zurück zum Zitat Zong JF, Peng YR, Bao GH, Hou RY, Wan XC (2016) Two new oleanane-type saponins with anti-proliferative activity from Camellia oleifera Abel. seed cake. Molecules 21:188PubMedCentralCrossRef Zong JF, Peng YR, Bao GH, Hou RY, Wan XC (2016) Two new oleanane-type saponins with anti-proliferative activity from Camellia oleifera Abel. seed cake. Molecules 21:188PubMedCentralCrossRef
Metadaten
Titel
Isolation and Characterization of Triterpenoid and Steroidal Saponins
verfasst von
Mostafa Abdelrahman
Sudisha Jogaiah
Copyright-Jahr
2020
DOI
https://doi.org/10.1007/978-3-030-61149-1_6

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