Skip to main content

2018 | OriginalPaper | Buchkapitel

Leishmaniasis Parasite Segmentation and Classification Using Deep Learning

verfasst von : Marc Górriz, Albert Aparicio, Berta Raventós, Verónica Vilaplana, Elisa Sayrol, Daniel López-Codina

Erschienen in: Articulated Motion and Deformable Objects

Verlag: Springer International Publishing

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Leishmaniasis is considered a neglected disease that causes thousands of deaths annually in some tropical and subtropical countries. There are various techniques to diagnose leishmaniasis of which manual microscopy is considered to be the gold standard. There is a need for the development of automatic techniques that are able to detect parasites in a robust and unsupervised manner. In this paper we present a procedure for automatizing the detection process based on a deep learning approach. We train a U-net model that successfully segments leismania parasites and classifies them into promastigotes, amastigotes and adhered parasites.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Farahi, M., Rabbani, H., Talebi, A., Sarrafzadeh, O., Ensafi, S.: Automatic segmentation of leishmania parasite in microscopic images using a modified CV level set method. In: Proceedings of the SPIE Seventh International Conference on Graphic and Image Processing, vol. 9817 (2015) Farahi, M., Rabbani, H., Talebi, A., Sarrafzadeh, O., Ensafi, S.: Automatic segmentation of leishmania parasite in microscopic images using a modified CV level set method. In: Proceedings of the SPIE Seventh International Conference on Graphic and Image Processing, vol. 9817 (2015)
2.
Zurück zum Zitat Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. In: Advances in Neural Information Processing Systems, pp. 1097–1105 (2012) Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. In: Advances in Neural Information Processing Systems, pp. 1097–1105 (2012)
3.
Zurück zum Zitat Mehanian, C., Jaiswal, M., Delahunt, C., Thompson, C., Horning, M., Hu, L., McGuire, S., Ostbye, T., Mehanian, M., Wilson, B., Champlin, C., Long, E., Proux, S., Gamboa, D., Chiodini, P., Carter, J., Dhorda, M., Isaboke, D., Ogutu, B., Oyibo, W., Villasis, E., Tun, K.M., Bachman, C., Bell, D.: Computer-automated malaria diagnosis and quantitation using convolutional neural networks. In: 2017 IEEE International Conference on Computer Vision Workshop (ICCVW), pp. 116–125 (2017) Mehanian, C., Jaiswal, M., Delahunt, C., Thompson, C., Horning, M., Hu, L., McGuire, S., Ostbye, T., Mehanian, M., Wilson, B., Champlin, C., Long, E., Proux, S., Gamboa, D., Chiodini, P., Carter, J., Dhorda, M., Isaboke, D., Ogutu, B., Oyibo, W., Villasis, E., Tun, K.M., Bachman, C., Bell, D.: Computer-automated malaria diagnosis and quantitation using convolutional neural networks. In: 2017 IEEE International Conference on Computer Vision Workshop (ICCVW), pp. 116–125 (2017)
4.
Zurück zum Zitat Ouertani, F., Amiri, H., Bettaib, J., Yazidi, R., Ben Salah, A.: Adaptive automatic segmentation of leishmaniasis parasite in indirect immunofluorescence images. In: Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2014) Ouertani, F., Amiri, H., Bettaib, J., Yazidi, R., Ben Salah, A.: Adaptive automatic segmentation of leishmaniasis parasite in indirect immunofluorescence images. In: Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2014)
5.
Zurück zum Zitat Ouertani, F., Amiri, H., Bettaib, J., Yazidi, R., Ben Salah, A.: Hybrid segmentation of fluorescent leschmania-infected images using a watersched and combined region merging based method. In: Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2016) Ouertani, F., Amiri, H., Bettaib, J., Yazidi, R., Ben Salah, A.: Hybrid segmentation of fluorescent leschmania-infected images using a watersched and combined region merging based method. In: Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2016)
6.
Zurück zum Zitat Penas, K.E., Rivera, P.T., Naval, P.C.: Malaria parasite detection and species identification on thin blood smears using a convolutional neural network. In: 2017 IEEE/ACM 10th International Workshop on Cooperative and Human Aspects of Software Engineering (CHASE), pp. 1–6 (2017) Penas, K.E., Rivera, P.T., Naval, P.C.: Malaria parasite detection and species identification on thin blood smears using a convolutional neural network. In: 2017 IEEE/ACM 10th International Workshop on Cooperative and Human Aspects of Software Engineering (CHASE), pp. 1–6 (2017)
7.
Zurück zum Zitat Quinn, J.A., Nakasi, R., Mugagga, P.K.B., Byanyima, P., Lubega, W., Andama, A.: Deep convolutional neural networks for microscopy-based point of care diagnostics. In: Proceedings of the 1st Machine Learning in Health Care, MLHC 2016, Los Angeles, CA, USA, 19–20 August 2016, pp. 271–281 (2016) Quinn, J.A., Nakasi, R., Mugagga, P.K.B., Byanyima, P., Lubega, W., Andama, A.: Deep convolutional neural networks for microscopy-based point of care diagnostics. In: Proceedings of the 1st Machine Learning in Health Care, MLHC 2016, Los Angeles, CA, USA, 19–20 August 2016, pp. 271–281 (2016)
9.
Zurück zum Zitat Sudre, C.H., Li, W., Vercauteren, T., Ourselin, S., Jorge Cardoso, M.: Generalised dice overlap as a deep learning loss function for highly unbalanced segmentations. In: Cardoso, M.J., Arbel, T., Carneiro, G., Syeda-Mahmood, T., Tavares, J.M.R.S., Moradi, M., Bradley, A., Greenspan, H., Papa, J.P., Madabhushi, A., Nascimento, J.C., Cardoso, J.S., Belagiannis, V., Lu, Z. (eds.) DLMIA/ML-CDS -2017. LNCS, vol. 10553, pp. 240–248. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-67558-9_28CrossRef Sudre, C.H., Li, W., Vercauteren, T., Ourselin, S., Jorge Cardoso, M.: Generalised dice overlap as a deep learning loss function for highly unbalanced segmentations. In: Cardoso, M.J., Arbel, T., Carneiro, G., Syeda-Mahmood, T., Tavares, J.M.R.S., Moradi, M., Bradley, A., Greenspan, H., Papa, J.P., Madabhushi, A., Nascimento, J.C., Cardoso, J.S., Belagiannis, V., Lu, Z. (eds.) DLMIA/ML-CDS -2017. LNCS, vol. 10553, pp. 240–248. Springer, Cham (2017). https://​doi.​org/​10.​1007/​978-3-319-67558-9_​28CrossRef
10.
Zurück zum Zitat Vazquez Noguera, J.L., Legal Ayala, H., Schaerer, C.E., Rolon, M.: Mathematical morphology for counting trypanosoma cruzi amastigotes. In: IEEE XXXIX Latin American Computing Conference (2013) Vazquez Noguera, J.L., Legal Ayala, H., Schaerer, C.E., Rolon, M.: Mathematical morphology for counting trypanosoma cruzi amastigotes. In: IEEE XXXIX Latin American Computing Conference (2013)
12.
Zurück zum Zitat Yazdanparast, E., Dos Anjos, A., Garcia, D., Loeuillet, C., Shahbazkia, H.R., Vergnes, B.: INsPECT, an open-source and versatile software for automated quantification of (leishmania) intracellular parasites. In: PLOS Neglected Tropical Diseases, vol. 8 (2014)CrossRef Yazdanparast, E., Dos Anjos, A., Garcia, D., Loeuillet, C., Shahbazkia, H.R., Vergnes, B.: INsPECT, an open-source and versatile software for automated quantification of (leishmania) intracellular parasites. In: PLOS Neglected Tropical Diseases, vol. 8 (2014)CrossRef
Metadaten
Titel
Leishmaniasis Parasite Segmentation and Classification Using Deep Learning
verfasst von
Marc Górriz
Albert Aparicio
Berta Raventós
Verónica Vilaplana
Elisa Sayrol
Daniel López-Codina
Copyright-Jahr
2018
DOI
https://doi.org/10.1007/978-3-319-94544-6_6

Premium Partner