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2014 | OriginalPaper | Buchkapitel

Linear Modeling and Prediction in Diabetes Physiology

verfasst von : Marzia Cescon, Rolf Johansson

Erschienen in: Data-driven Modeling for Diabetes

Verlag: Springer Berlin Heidelberg

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Abstract

Diabetes Mellitus is a chronic disease characterized by the inability of the organism to autonomously regulate the blood glucose level due to insulin deficiency or resistance, leading to serious health damages. The therapy is essentially based on insulin injections and depends strongly on patient daily decisions, being mainly based upon empirical experience and rules of thumb. This chapter presents work on data-driven glucose metabolism modeling and short-term, that is, up to 120 min, blood-glucose prediction in Type 1 Diabetes Mellitus (T1DM) subjects. Low-order, individualized, data-driven, stable, physiologically relevant models were identified from a population of 9 datasets from T1DM patients. Model structures include: autoregressive moving average with exogenous inputs (ARMAX) models and state-space models. The performances of the model-based predictors were compared to those achieved by the zero-order hold (ZOH).

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Metadaten
Titel
Linear Modeling and Prediction in Diabetes Physiology
verfasst von
Marzia Cescon
Rolf Johansson
Copyright-Jahr
2014
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-54464-4_9

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