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Erschienen in:
2006 | OriginalPaper | Buchkapitel
A Unifying View of Genome Rearrangements
verfasst von : Anne Bergeron, Julia Mixtacki, Jens Stoye
Erschienen in: Algorithms in Bioinformatics
Verlag: Springer Berlin Heidelberg
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Genome rearrangements have been modeled by a variety of operations such as inversions, translocations, fissions, fusions, transpositions and block interchanges. The
double cut and join
operation, introduced by Yancopoulos
et al.
, allows to model all the classical operations while simplifying the algorithms. In this paper we show a simple way to apply this operation to the most general type of genomes with a mixed collection of linear and circular chromosomes. We also describe a graph structure that allows simplifying the theory and distance computation considerably, as neither capping nor concatenation of the linear chromosomes are necessary.