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Erschienen in:
2006 | OriginalPaper | Buchkapitel
Tumor Therapeutic Response and Vessel Tortuosity: Preliminary Report in Metastatic Breast Cancer
verfasst von : Elizabeth Bullitt, Nancy U. Lin, Matthew G. Ewend, Donglin Zeng, Eric P. Winer, Lisa A. Carey, J. Keith Smith
Erschienen in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006
Verlag: Springer Berlin Heidelberg
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No current non-invasive method is capable of assessing the efficacy of brain tumor therapy early during treatment. We outline an approach that evaluates tumor activity via statistical analysis of vessel shape using vessels segmented from MRA. This report is the first to describe the changes in vessel shape that occur during treatment of metastatic brain tumors as assessed by sequential MRA. In this preliminary study of 16 patients undergoing treatment for metastatic breast cancer we conclude that vessel shape may predict tumor response several months in advance of traditional methods.