Skip to main content

2016 | OriginalPaper | Buchkapitel

Longitudinal Multiple Sclerosis Lesion Segmentation Using Multi-view Convolutional Neural Networks

verfasst von : Ariel Birenbaum, Hayit Greenspan

Erschienen in: Deep Learning and Data Labeling for Medical Applications

Verlag: Springer International Publishing

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Automatic segmentation of Multiple Sclerosis (MS) lesions is a challenging task due to their variability in shape, size, location and texture in Magnetic Resonance (MR) images. A reliable, automatic segmentation method can help diagnosis and patient follow-up while reducing the time consuming need of manual segmentation. In this paper, we present a fully automated method for MS lesion segmentation. The proposed method uses MR intensities and White Matter (WM) priors for extraction of candidate lesion voxels and uses Convolutional Neural Networks for false positive reduction. Our networks process longitudinal data, a novel contribution in the domain of MS lesion analysis. The method was tested on the ISBI 2015 dataset and obtained state-of-the-art Dice results with the performance level of a trained human rater.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Aït-Ali, L.S., Prima, S., Hellier, P., Carsin, B., Edan, G., Barillot, C.: STREM: a robust multidimensional parametric method to segment MS lesions in MRI. In: Duncan, J.S., Gerig, G. (eds.) MICCAI 2005. LNCS, vol. 3749, pp. 409–416. Springer, Heidelberg (2005)CrossRef Aït-Ali, L.S., Prima, S., Hellier, P., Carsin, B., Edan, G., Barillot, C.: STREM: a robust multidimensional parametric method to segment MS lesions in MRI. In: Duncan, J.S., Gerig, G. (eds.) MICCAI 2005. LNCS, vol. 3749, pp. 409–416. Springer, Heidelberg (2005)CrossRef
2.
Zurück zum Zitat Styner, M., Lee, J., Chin, B., et al.: 3D segmentation in the clinic: a grand challenge II: MS lesion segmentation. MIDAS J. 2008, 1–5 (2008) Styner, M., Lee, J., Chin, B., et al.: 3D segmentation in the clinic: a grand challenge II: MS lesion segmentation. MIDAS J. 2008, 1–5 (2008)
3.
Zurück zum Zitat Maier, O., Handels, H.: MS-Lesion Segmentation in MRI with Random Forests. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015) Maier, O., Handels, H.: MS-Lesion Segmentation in MRI with Random Forests. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015)
4.
Zurück zum Zitat Catanese, L., Commowick, O., Barillot, C.: Automatic graph cut segmentation of multiple Sclerosis lesions. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015) Catanese, L., Commowick, O., Barillot, C.: Automatic graph cut segmentation of multiple Sclerosis lesions. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015)
5.
Zurück zum Zitat Ghafoorian, M., Platel, B.: Convolutional neural networks for MS lesion segmentation, method description of DIAG team. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015) Ghafoorian, M., Platel, B.: Convolutional neural networks for MS lesion segmentation, method description of DIAG team. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015)
6.
Zurück zum Zitat Vaidya, S., et al.: Longitudinal multiple Sclerosis lesion segmentation using 3D convolutional neural networks. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015) Vaidya, S., et al.: Longitudinal multiple Sclerosis lesion segmentation using 3D convolutional neural networks. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015)
7.
Zurück zum Zitat Jesson, A., Arbel, T.: Hierarchical MRF and random forest segmentation of MS lesions and healthy tissues in brain MRI. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015) Jesson, A., Arbel, T.: Hierarchical MRF and random forest segmentation of MS lesions and healthy tissues in brain MRI. In: Proceedings of the 2015 Longitudinal Multiple Sclerosis Lesion Segmentation Challenge, pp. 1–2 (2015)
8.
Zurück zum Zitat Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. In: Advances in Neural Information Processing Systems, pp. 1097–1105 (2012) Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. In: Advances in Neural Information Processing Systems, pp. 1097–1105 (2012)
9.
Zurück zum Zitat Roth, H.R., et al.: A new 2.5D representation for lymph node detection using random sets of deep convolutional neural network observations. In: Golland, P., Hata, N., Barillot, C., Hornegger, J., Howe, R. (eds.) MICCAI 2014, Part I. LNCS, vol. 8673, pp. 520–527. Springer, Heidelberg (2014) Roth, H.R., et al.: A new 2.5D representation for lymph node detection using random sets of deep convolutional neural network observations. In: Golland, P., Hata, N., Barillot, C., Hornegger, J., Howe, R. (eds.) MICCAI 2014, Part I. LNCS, vol. 8673, pp. 520–527. Springer, Heidelberg (2014)
10.
Zurück zum Zitat Mechrez, R., Goldberger, J., Greenspan, H.: Patch-based segmentation with spatial consistency: application to MS lesions in brain MRI. Int. J. Biomed. Imaging 2016, 1–13 (2016)CrossRef Mechrez, R., Goldberger, J., Greenspan, H.: Patch-based segmentation with spatial consistency: application to MS lesions in brain MRI. Int. J. Biomed. Imaging 2016, 1–13 (2016)CrossRef
11.
Zurück zum Zitat Mazziotta, J., Toga, A., Evans, A., et al.: A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM). Philos. Trans. Roy. Soc. Lond. Ser. B 356(1412), 1293–1322 (2001)CrossRef Mazziotta, J., Toga, A., Evans, A., et al.: A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM). Philos. Trans. Roy. Soc. Lond. Ser. B 356(1412), 1293–1322 (2001)CrossRef
12.
Zurück zum Zitat Srivastava, N., Hinton, G., Krizhevsky, A., Sutskever, I., Salakhutdinov, R.: Dropout: a simple way to prevent neural networks from overfitting. J. Mach. Learn. Res. 15, 1929–1958 (2014)MathSciNetMATH Srivastava, N., Hinton, G., Krizhevsky, A., Sutskever, I., Salakhutdinov, R.: Dropout: a simple way to prevent neural networks from overfitting. J. Mach. Learn. Res. 15, 1929–1958 (2014)MathSciNetMATH
15.
Zurück zum Zitat Roy, S., et al.: Subject-specific sparse dictionary learning for atlas-based brain MRI segmentation. IEEE J. Biomed. Health Inform. 19(5), 1598–1609 (2015)CrossRef Roy, S., et al.: Subject-specific sparse dictionary learning for atlas-based brain MRI segmentation. IEEE J. Biomed. Health Inform. 19(5), 1598–1609 (2015)CrossRef
17.
Zurück zum Zitat Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015) Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)
18.
Zurück zum Zitat Setio, A.A.A., et al.: Pulmonary nodule detection in CT images: false positive reduction using multi-view convolutional networks. IEEE Trans. Med. Imaging 35(5), 1160–1169 (2016)CrossRef Setio, A.A.A., et al.: Pulmonary nodule detection in CT images: false positive reduction using multi-view convolutional networks. IEEE Trans. Med. Imaging 35(5), 1160–1169 (2016)CrossRef
Metadaten
Titel
Longitudinal Multiple Sclerosis Lesion Segmentation Using Multi-view Convolutional Neural Networks
verfasst von
Ariel Birenbaum
Hayit Greenspan
Copyright-Jahr
2016
DOI
https://doi.org/10.1007/978-3-319-46976-8_7