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2018 | OriginalPaper | Buchkapitel

Maize Gene Regulatory Relationship Mining Using Association Rule

verfasst von : Jianxiao Liu, Chaoyang Wang, Haijun Liu, Yingjie Xiao, Songlin Hao, Xiaolong Zhang, Jianchao Sun, Huan Yu

Erschienen in: Computational Intelligence and Intelligent Systems

Verlag: Springer Singapore

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Abstract

How to mine the gene regulatory relationship, and thus to construct gene regulatory network (GRN) is of utmost interest and has become a challenging computational problem for understanding the complex regulatory mechanisms in cellular systems. In this work, we use the association rule mining method to infer the gene regulatory relationship through the steps of mining frequent set, generating rules and rule merging. This method can not only get different types of gene regulatory relationships, but also get regulatory direction among genes. Experiment results show the effectiveness of this method. In all, the association rule mining method can effectively mine gene regulatory relationships of our maize gene expression dataset.

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Literatur
1.
Zurück zum Zitat Shmulevich, I., Dougherty, E., Zhang, W.: From Boolean to probabilistic Boolean networks as models of genetic regulatory networks. Proc. IEEE 90, 1778–1792 (2002)CrossRef Shmulevich, I., Dougherty, E., Zhang, W.: From Boolean to probabilistic Boolean networks as models of genetic regulatory networks. Proc. IEEE 90, 1778–1792 (2002)CrossRef
2.
Zurück zum Zitat Sakamoto, E., Iba, H.: Inferring a system of differential equations for a gene regulatory network by using genetic programming. In: Proceedings of the 2001 Congress on Evolutionary Computation, vol. 1, pp. 720–726 (2001) Sakamoto, E., Iba, H.: Inferring a system of differential equations for a gene regulatory network by using genetic programming. In: Proceedings of the 2001 Congress on Evolutionary Computation, vol. 1, pp. 720–726 (2001)
3.
Zurück zum Zitat Gardner, T., Di Bernardo, D., Lorenz, D.: Inferring genetic networks and identifying compound mode of action via expression profiling. Science 301, 102–105 (2003)CrossRef Gardner, T., Di Bernardo, D., Lorenz, D.: Inferring genetic networks and identifying compound mode of action via expression profiling. Science 301, 102–105 (2003)CrossRef
4.
Zurück zum Zitat Margolin, A., Nemenman, I., Basso, K.: ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinform. 7, S7 (2006)CrossRef Margolin, A., Nemenman, I., Basso, K.: ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinform. 7, S7 (2006)CrossRef
5.
Zurück zum Zitat Zhang, X., Zhao, X., He, K.: Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information. Bioinformatics 28, 98–104 (2012)CrossRef Zhang, X., Zhao, X., He, K.: Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information. Bioinformatics 28, 98–104 (2012)CrossRef
6.
Zurück zum Zitat Zhang, X., Zhao, J., Hao, J.: Conditional mutual inclusive information enables accurate quantification of associations in gene regulatory networks. Nucleic Acids Res. 43, e31 (2015)CrossRef Zhang, X., Zhao, J., Hao, J.: Conditional mutual inclusive information enables accurate quantification of associations in gene regulatory networks. Nucleic Acids Res. 43, e31 (2015)CrossRef
7.
Zurück zum Zitat Chen, X., Anantha, G., Wang, X.: An effective structure learning method for constructing gene networks. Bioinformatics 22, 1367–1374 (2006)CrossRef Chen, X., Anantha, G., Wang, X.: An effective structure learning method for constructing gene networks. Bioinformatics 22, 1367–1374 (2006)CrossRef
8.
Zurück zum Zitat Czibula, G., Bocicor, M., Czibula, I.: Promoter sequences prediction using relational association rule mining. Evol. Bioinform. Online 8, 181 (2012)CrossRef Czibula, G., Bocicor, M., Czibula, I.: Promoter sequences prediction using relational association rule mining. Evol. Bioinform. Online 8, 181 (2012)CrossRef
9.
Zurück zum Zitat Iltanen, K., Kiviharju, S., Ao, L.: Clustering and summarising association rules mined from phenotype, genotype and environmental data concerning age-related hearing impairment. In: MedInfo, pp. 452–456 (2013) Iltanen, K., Kiviharju, S., Ao, L.: Clustering and summarising association rules mined from phenotype, genotype and environmental data concerning age-related hearing impairment. In: MedInfo, pp. 452–456 (2013)
10.
Zurück zum Zitat Sengupta, D., Sood, M., Vijayvargia, P.: Association rule mining based study for identification of clinical parameters akin to occurrence of brain tumor. Bioinformation 9, 555 (2013)CrossRef Sengupta, D., Sood, M., Vijayvargia, P.: Association rule mining based study for identification of clinical parameters akin to occurrence of brain tumor. Bioinformation 9, 555 (2013)CrossRef
11.
Zurück zum Zitat Jung, S., Son, C., Kim, M.: Association rules to identify complications of cerebral infarction in patients with atrial fibrillation. Healthc. Inform. Res. 19, 25–32 (2013)CrossRef Jung, S., Son, C., Kim, M.: Association rules to identify complications of cerebral infarction in patients with atrial fibrillation. Healthc. Inform. Res. 19, 25–32 (2013)CrossRef
12.
Zurück zum Zitat Gong, L., Yan, Y., Xie, J.: Prediction of autism susceptibility genes based on association rules. J. Neurosci. Res. 90, 1119–1125 (2012)CrossRef Gong, L., Yan, Y., Xie, J.: Prediction of autism susceptibility genes based on association rules. J. Neurosci. Res. 90, 1119–1125 (2012)CrossRef
13.
Zurück zum Zitat Giugno, R., Pulvirenti, A., Cascione, L.: MIDClass: microarray data classification by association rules and gene expression intervals. PLoS ONE 8, e69873 (2013)CrossRef Giugno, R., Pulvirenti, A., Cascione, L.: MIDClass: microarray data classification by association rules and gene expression intervals. PLoS ONE 8, e69873 (2013)CrossRef
14.
Zurück zum Zitat Sethi, P., Alagiriswamy, S.: Association rule based similarity measures for the clustering of gene expression data. Open Med. Inform. J. 4, 63 (2010)CrossRef Sethi, P., Alagiriswamy, S.: Association rule based similarity measures for the clustering of gene expression data. Open Med. Inform. J. 4, 63 (2010)CrossRef
15.
Zurück zum Zitat Fu, J., Cheng, Y., Linghu, J.: RNA sequencing reveals the complex regulatory network in the maize kernel. Nat. Commun. 4, 2832 (2013)CrossRef Fu, J., Cheng, Y., Linghu, J.: RNA sequencing reveals the complex regulatory network in the maize kernel. Nat. Commun. 4, 2832 (2013)CrossRef
16.
Zurück zum Zitat Yang, X., Gao, S., Xu, S., Zhang, Z., Prasanna, B., Li, L., Li, J., Yan, J.: Characterization of a global germplasm collection and its potential utilization for analysis of complex quantitative traits in maize. Mol. Breed. 28, 511–526 (2011)CrossRef Yang, X., Gao, S., Xu, S., Zhang, Z., Prasanna, B., Li, L., Li, J., Yan, J.: Characterization of a global germplasm collection and its potential utilization for analysis of complex quantitative traits in maize. Mol. Breed. 28, 511–526 (2011)CrossRef
Metadaten
Titel
Maize Gene Regulatory Relationship Mining Using Association Rule
verfasst von
Jianxiao Liu
Chaoyang Wang
Haijun Liu
Yingjie Xiao
Songlin Hao
Xiaolong Zhang
Jianchao Sun
Huan Yu
Copyright-Jahr
2018
Verlag
Springer Singapore
DOI
https://doi.org/10.1007/978-981-13-1648-7_21