Skip to main content
Erschienen in: Journal of Nanoparticle Research 10/2012

01.10.2012 | Research Paper

Merit and demerit effects of silver nanoparticles in the bioperformance of an electrodeposited hydroxyapatite: nanosilver composite coating

verfasst von: D. Ionita, M. Dilea, I. Titorencu, I. Demetrescu

Erschienen in: Journal of Nanoparticle Research | Ausgabe 10/2012

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

For this research, TiAlZr specimens were covered with a hydroxyapatite–silver nanoparticles composite coatings (nAg-HA) prepared by pulse electrodeposition. The morphological texture of the nAg-HA nanoparticles on TiAlZr surface was investigated with scanning electron microscopy and energy dispersive X-ray spectroscopy. Electrochemical parameters from dynamic polarization tests performed in Ringer’s solution indicate better anticorrosive properties for the TiAlZr alloy after nAg-HA electrodeposition. Bacteriological experiments performed in vitro demonstrate the efficacy of TiAlZr implants coated with nAg-HA against the growth of Escherichia coli bacteria quantified in a 98 % inhibition of Escherichia coli growth. The biocompatibility tests regarding cell adherence, proliferation, and viability of coating (also by means of Reverse Transcription Polymerase Chain Reaction—RT-PCR) completed the characterization of the coating, enabling us to discuss the merit and demerit effects of Ag nanoparticles (nAg) effects on bioperformance. Based on experimental and literature data, the coating could be considered a passive–active structure.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
Zurück zum Zitat Aillon KL, Xie Y, El-Gendy N, Berkland CJ, Forrest ML (2009) Effects of nanomaterial physicochemical properties on in vivo toxicity. Adv Drug Deliv Rev 61:457–466CrossRef Aillon KL, Xie Y, El-Gendy N, Berkland CJ, Forrest ML (2009) Effects of nanomaterial physicochemical properties on in vivo toxicity. Adv Drug Deliv Rev 61:457–466CrossRef
Zurück zum Zitat AshaRani PV, Low Kah Mun G, Hande MP, Valiyaveettil S (2009) Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 3:279–290CrossRef AshaRani PV, Low Kah Mun G, Hande MP, Valiyaveettil S (2009) Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 3:279–290CrossRef
Zurück zum Zitat Balagna C, Vitale-Brovarone C, Miola M, Verne E, Canuto RA, Saracino S, Muzio G, Fucale G, Maina G (2011) Biocompatibility and antibacterial effect of silver doped 3D-glass-ceramic scaffolds for bone grafting. J Biomater Appl 25:595–617CrossRef Balagna C, Vitale-Brovarone C, Miola M, Verne E, Canuto RA, Saracino S, Muzio G, Fucale G, Maina G (2011) Biocompatibility and antibacterial effect of silver doped 3D-glass-ceramic scaffolds for bone grafting. J Biomater Appl 25:595–617CrossRef
Zurück zum Zitat Ballare J, Manjubala I, Schreiner WH, Orellano JC, Fratzl P, Cere S (2010) Improving the osteointegration and bone–implant interface by incorporation of bioactive particles in sol–gel coatings of stainless steel implants. Acta Biomater 6:1601–1609CrossRef Ballare J, Manjubala I, Schreiner WH, Orellano JC, Fratzl P, Cere S (2010) Improving the osteointegration and bone–implant interface by incorporation of bioactive particles in sol–gel coatings of stainless steel implants. Acta Biomater 6:1601–1609CrossRef
Zurück zum Zitat Cao XL, Cheng C, Ma YL, Zhao CS (2010) Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities. J Mater Sci Mater Med 21:2861–2868CrossRef Cao XL, Cheng C, Ma YL, Zhao CS (2010) Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities. J Mater Sci Mater Med 21:2861–2868CrossRef
Zurück zum Zitat Chen Y, Zheng X, Xie Y, Ding C, Ruan H, Fan C (2008) Anti-bacterial and cytotoxic properties of plasma sprayed silver-containing HA coatings. J Mater Sci Mater Med 19:3603–3609CrossRef Chen Y, Zheng X, Xie Y, Ding C, Ruan H, Fan C (2008) Anti-bacterial and cytotoxic properties of plasma sprayed silver-containing HA coatings. J Mater Sci Mater Med 19:3603–3609CrossRef
Zurück zum Zitat Chen Y, Zheng X, Xie Y, Ji H, Ding C (2009) Antibacterial properties of vacuum plasma sprayed titanium coatings after chemical treatment. Surf Coat Technol 204:685–690CrossRef Chen Y, Zheng X, Xie Y, Ji H, Ding C (2009) Antibacterial properties of vacuum plasma sprayed titanium coatings after chemical treatment. Surf Coat Technol 204:685–690CrossRef
Zurück zum Zitat Demetrescu I (2008) Passive and bioactive films on implant materials and their efficiency in regenerative medicine. Mol Cryst Liq Cryst 486:110–119CrossRef Demetrescu I (2008) Passive and bioactive films on implant materials and their efficiency in regenerative medicine. Mol Cryst Liq Cryst 486:110–119CrossRef
Zurück zum Zitat Demetrescu I, Pirvu C, Mitran V (2010) Effect of nano: topographical features of Ti/TiO2 electrode surface on cell response and electrochemical stability in artificial saliva. Bioelectrochemistry 79:122–129CrossRef Demetrescu I, Pirvu C, Mitran V (2010) Effect of nano: topographical features of Ti/TiO2 electrode surface on cell response and electrochemical stability in artificial saliva. Bioelectrochemistry 79:122–129CrossRef
Zurück zum Zitat Hoonacker AV, Englebienne P (2006) Revisiting silver nanoparticle chemical synthesis and stability by optical spectroscopy. Curr Nanosci 2:359–371CrossRef Hoonacker AV, Englebienne P (2006) Revisiting silver nanoparticle chemical synthesis and stability by optical spectroscopy. Curr Nanosci 2:359–371CrossRef
Zurück zum Zitat Hsu SH, Tseng HJ, Lin YC (2010) The biocompatibility and antibacterial properties of waterborne polyurethane-silver nanocomposites. Biomaterials 31:6796–6808CrossRef Hsu SH, Tseng HJ, Lin YC (2010) The biocompatibility and antibacterial properties of waterborne polyurethane-silver nanocomposites. Biomaterials 31:6796–6808CrossRef
Zurück zum Zitat Hussain SM, Hess KL, Gearhart JM, Geiss KT, Schlager JJ (2005) In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol In Vitro 19:975–983CrossRef Hussain SM, Hess KL, Gearhart JM, Geiss KT, Schlager JJ (2005) In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol In Vitro 19:975–983CrossRef
Zurück zum Zitat Iafisco M, Bosco R, Leeuwenburgh SCG, Van den Beucken JJJP, Jansen JA, Prat M, Roveri N (2011) Electrostatic spray deposition of biomimetic nanocrystalline apatite coatings onto titanium. Adv Eng Mater. doi:10.1002/adem.201180062 Iafisco M, Bosco R, Leeuwenburgh SCG, Van den Beucken JJJP, Jansen JA, Prat M, Roveri N (2011) Electrostatic spray deposition of biomimetic nanocrystalline apatite coatings onto titanium. Adv Eng Mater. doi:10.​1002/​adem.​201180062
Zurück zum Zitat Ionita D, Grecu M, Ungureanu C, Demetrescu I (2011a) Antimicrobial activity of the surface coatings on TiAlZr implant biomaterial. J Biosci Bioeng 112:6630–6634CrossRef Ionita D, Grecu M, Ungureanu C, Demetrescu I (2011a) Antimicrobial activity of the surface coatings on TiAlZr implant biomaterial. J Biosci Bioeng 112:6630–6634CrossRef
Zurück zum Zitat Ionita D, Grecu M, Ungureanu C, Demetrescu I (2011b) Modifying the TiAlZr biomaterial surface with coating, for a better anticorrosive and antibacterial performance. Appl Surf Sci 257:9164–9168CrossRef Ionita D, Grecu M, Ungureanu C, Demetrescu I (2011b) Modifying the TiAlZr biomaterial surface with coating, for a better anticorrosive and antibacterial performance. Appl Surf Sci 257:9164–9168CrossRef
Zurück zum Zitat Kunin CM (1987) Detection, prevention and management of urinary tract infection. Lea & Febiger, Philadelphia, PA Kunin CM (1987) Detection, prevention and management of urinary tract infection. Lea & Febiger, Philadelphia, PA
Zurück zum Zitat Lubick N (2008) Nanosilver toxicity: ions, nanoparticles—or both? Environ Sci Technol 42:8617CrossRef Lubick N (2008) Nanosilver toxicity: ions, nanoparticles—or both? Environ Sci Technol 42:8617CrossRef
Zurück zum Zitat Marambio-Jones C, Hoek EMV (2010) A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment. J Nanopart Res 12:1531–1551CrossRef Marambio-Jones C, Hoek EMV (2010) A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment. J Nanopart Res 12:1531–1551CrossRef
Zurück zum Zitat Maury F, Mungkalasari J (2009) Chemical vapor deposition of TiO2 for photocatalytic applications and biocidal surfaces. Key Eng Mater 415:1–4CrossRef Maury F, Mungkalasari J (2009) Chemical vapor deposition of TiO2 for photocatalytic applications and biocidal surfaces. Key Eng Mater 415:1–4CrossRef
Zurück zum Zitat Moa A, Liao J, Xu W, Xian S, Li Y, Bai S (2008) Preparation and antibacterial effect of silver–hydroxyapatite/titania nanocomposite thin film on titanium. Appl Surf Sci 255:435–438CrossRef Moa A, Liao J, Xu W, Xian S, Li Y, Bai S (2008) Preparation and antibacterial effect of silver–hydroxyapatite/titania nanocomposite thin film on titanium. Appl Surf Sci 255:435–438CrossRef
Zurück zum Zitat Morgan MLD (1998) Tetrazolium (MTT) Assay for cellular viability and activity methods. In: Mol. Biol., Polyamine protocols, Part VI, ed. Humana Press Inc. pp 179–184 Morgan MLD (1998) Tetrazolium (MTT) Assay for cellular viability and activity methods. In: Mol. Biol., Polyamine protocols, Part VI, ed. Humana Press Inc. pp 179–184
Zurück zum Zitat Narayan RJ, Monteiro-Riviere NA, Brigmon RL, Pellin MJ, Elam JW (2009) Atomic layer deposition of TiO2 thin films on nanoporous alumina templates: medical applications. JOM J Miner Metall Mater 61:12–16CrossRef Narayan RJ, Monteiro-Riviere NA, Brigmon RL, Pellin MJ, Elam JW (2009) Atomic layer deposition of TiO2 thin films on nanoporous alumina templates: medical applications. JOM J Miner Metall Mater 61:12–16CrossRef
Zurück zum Zitat Narayanan R, Seshadri SK (2008) Point defect model and corrosion of anodic oxide coatings on Ti–6Al–4 V. Corros Sci 50:1521–1529CrossRef Narayanan R, Seshadri SK (2008) Point defect model and corrosion of anodic oxide coatings on Ti–6Al–4 V. Corros Sci 50:1521–1529CrossRef
Zurück zum Zitat Nel A, Xia T, Madler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311:622–627CrossRef Nel A, Xia T, Madler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311:622–627CrossRef
Zurück zum Zitat Oliveira PT, Zalzal SF, Irie K, Nanci A (2003) Early expression of bone matrix proteins in osteogenic cell cultures. J Histochem Cytochem 51:633–641CrossRef Oliveira PT, Zalzal SF, Irie K, Nanci A (2003) Early expression of bone matrix proteins in osteogenic cell cultures. J Histochem Cytochem 51:633–641CrossRef
Zurück zum Zitat Papp T, Schiffmann D, Weiss D, Castranova V, Vallyathan V, Rahman Q (2008) Human health implications of nanomaterial exposure. Nanotoxicology 2:9–27CrossRef Papp T, Schiffmann D, Weiss D, Castranova V, Vallyathan V, Rahman Q (2008) Human health implications of nanomaterial exposure. Nanotoxicology 2:9–27CrossRef
Zurück zum Zitat Park EJ, Yi J, Kim Y, Choi K, Park K (2010) Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. Toxicol In Vitro 24:872–878CrossRef Park EJ, Yi J, Kim Y, Choi K, Park K (2010) Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. Toxicol In Vitro 24:872–878CrossRef
Zurück zum Zitat Popa MV, Demetrescu I, Suh SH, Vasilescu E, Drob P, Ionita D, Vasilescu C (2007) Monitoring of titanium base alloys–biofluids interface. Bioelectrochemistry 71:126–134CrossRef Popa MV, Demetrescu I, Suh SH, Vasilescu E, Drob P, Ionita D, Vasilescu C (2007) Monitoring of titanium base alloys–biofluids interface. Bioelectrochemistry 71:126–134CrossRef
Zurück zum Zitat Rameshbabu N, Kumar TSS, Prabhakar TG, Sastry VS, Murty KVGK, Rao KP (2007) Antibacterial nanosized silver substituted hydroxyapatite: synthesis and characterization. J Biomed Mater Res-A 80A:581–591CrossRef Rameshbabu N, Kumar TSS, Prabhakar TG, Sastry VS, Murty KVGK, Rao KP (2007) Antibacterial nanosized silver substituted hydroxyapatite: synthesis and characterization. J Biomed Mater Res-A 80A:581–591CrossRef
Zurück zum Zitat Roco MC (2004) Nanoscale science and engineering: unifying and transforming tools. AIChE J 50:890–897CrossRef Roco MC (2004) Nanoscale science and engineering: unifying and transforming tools. AIChE J 50:890–897CrossRef
Zurück zum Zitat Simchi A, Tamjid E, Pishbin F, Boccaccini AR (2011) Recent progress in inorganic and composite coatings with bactericidal capability for orthopaedic applications. Nanomed 7:22–39CrossRef Simchi A, Tamjid E, Pishbin F, Boccaccini AR (2011) Recent progress in inorganic and composite coatings with bactericidal capability for orthopaedic applications. Nanomed 7:22–39CrossRef
Zurück zum Zitat Sondi I, Salopek-Sondi B (2004) Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. J Colloid Interface Sci 275:177–182CrossRef Sondi I, Salopek-Sondi B (2004) Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. J Colloid Interface Sci 275:177–182CrossRef
Zurück zum Zitat Sotiriou GA, Pratsinis SE (2010) Antibacterial activity of nanosilver ions and particles. Environ Sci Technol 44:5649–5654CrossRef Sotiriou GA, Pratsinis SE (2010) Antibacterial activity of nanosilver ions and particles. Environ Sci Technol 44:5649–5654CrossRef
Zurück zum Zitat Stickler DJ (2000) Biomaterials to prevent nosocomial infections: is silver the gold standard? Curr Opin Infect Dis 13:389–393CrossRef Stickler DJ (2000) Biomaterials to prevent nosocomial infections: is silver the gold standard? Curr Opin Infect Dis 13:389–393CrossRef
Zurück zum Zitat Stratton TR, Howarter JA, Allison BC, Applegate BM, Youngblood JP (2010) Structure–activity relationships of antibacterial and biocompatible copolymers. Biomacromolecules 11:1286–1290CrossRef Stratton TR, Howarter JA, Allison BC, Applegate BM, Youngblood JP (2010) Structure–activity relationships of antibacterial and biocompatible copolymers. Biomacromolecules 11:1286–1290CrossRef
Zurück zum Zitat Subramanian V, Youtie J, Porter AL, Shapira P (2010) Is there a shift to “active nanostructures”? J Nanopart Res 12:1–10CrossRef Subramanian V, Youtie J, Porter AL, Shapira P (2010) Is there a shift to “active nanostructures”? J Nanopart Res 12:1–10CrossRef
Zurück zum Zitat Sung JH, Ji JH, Park JD, Yoon JU, Kim DS, Jeon KS, Song MY, Jeong J et al (2009) Subchronic inhalation toxicity of silver nanoparticles. Toxicol Sci 108:452–461CrossRef Sung JH, Ji JH, Park JD, Yoon JU, Kim DS, Jeon KS, Song MY, Jeong J et al (2009) Subchronic inhalation toxicity of silver nanoparticles. Toxicol Sci 108:452–461CrossRef
Zurück zum Zitat Titorencu I, Jinga VV, Constantinescu E, Gafencu AV, Ciohodaru C, Manolescu I, Zaharia C, Simionescu M (2007) Proliferation, differentiation and characterization of osteoblasts from human bone marrow mesenchymal cells. Cytotherapy 9:682–696CrossRef Titorencu I, Jinga VV, Constantinescu E, Gafencu AV, Ciohodaru C, Manolescu I, Zaharia C, Simionescu M (2007) Proliferation, differentiation and characterization of osteoblasts from human bone marrow mesenchymal cells. Cytotherapy 9:682–696CrossRef
Zurück zum Zitat Vasilescu C, Drob P, Vasilescu E, Demetrescu I, Ionita D, Prodana M, Drob SI (2011) Characterisation and corrosion resistance of the electrodeposited hydroxyapatite and bovine serum albumin/hydroxyapatite films on Ti–6Al–4 V–1Zr alloy surface. Corros Sci 53:992–999CrossRef Vasilescu C, Drob P, Vasilescu E, Demetrescu I, Ionita D, Prodana M, Drob SI (2011) Characterisation and corrosion resistance of the electrodeposited hydroxyapatite and bovine serum albumin/hydroxyapatite films on Ti–6Al–4 V–1Zr alloy surface. Corros Sci 53:992–999CrossRef
Zurück zum Zitat Watari F (2010) Bioreactive nature of nanobiomaterials. Nanobiomedicine 1:2–8 Watari F (2010) Bioreactive nature of nanobiomaterials. Nanobiomedicine 1:2–8
Zurück zum Zitat Watari F, Takashi N, Yokoyama A, Uo M, Akasaka T, Sato T, Abe S, Totsuka Tohji K (2009) Material nanosizing effect on living organisms: non-specific, biointeractive, physical size effects. J R Soc Interface 6:371–388CrossRef Watari F, Takashi N, Yokoyama A, Uo M, Akasaka T, Sato T, Abe S, Totsuka Tohji K (2009) Material nanosizing effect on living organisms: non-specific, biointeractive, physical size effects. J R Soc Interface 6:371–388CrossRef
Zurück zum Zitat Yaser G, Melanie JC, Karin AH, Gordon WB (2012) Development of a hydroxyapatite coating containing silver for the prevention of peri-prosthetic infection. J Orthop Res 30:356–363CrossRef Yaser G, Melanie JC, Karin AH, Gordon WB (2012) Development of a hydroxyapatite coating containing silver for the prevention of peri-prosthetic infection. J Orthop Res 30:356–363CrossRef
Metadaten
Titel
Merit and demerit effects of silver nanoparticles in the bioperformance of an electrodeposited hydroxyapatite: nanosilver composite coating
verfasst von
D. Ionita
M. Dilea
I. Titorencu
I. Demetrescu
Publikationsdatum
01.10.2012
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 10/2012
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-012-1152-6

Weitere Artikel der Ausgabe 10/2012

Journal of Nanoparticle Research 10/2012 Zur Ausgabe

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.