Skip to main content
Erschienen in: Network Modeling Analysis in Health Informatics and Bioinformatics 1/2016

01.12.2016 | Original Article

MetaG: a graph-based metagenomic gene analysis for big DNA data

verfasst von: Linkon Chowdhury, Mohammad Ibrahim Khan, Kaushik Deb, Sarwar Kamal

Erschienen in: Network Modeling Analysis in Health Informatics and Bioinformatics | Ausgabe 1/2016

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Microbial interactions and relationships are significant for animals, insects and plants. Metagenomic research enables properassessments and analysis for microbial organs and communities. The analysis helps to gain detailed insights on miscopies insects. Recent machine learning techniques focused on algorithms and data mining tools to check the depth of interactions and relationships on metagenomic dataset. Accurate analysis over large genes helps to solve real-world problems for public interest. In this regard, graph-centric big gene dataset representations are very important. De Bruijn graph is one the pivotal media to demonstrate the relationships and interactions of large genes dataset or metagenomic dataset. In this research, mapping-based metagenomic graphical (MetaG) genomes representation has been demonstrated. Data cleaning is done before applying graphical illustration. Random mapping is used to assess the variations in dataset. Euler path-based De Bruijn graph is used to sketch the gene annotation, translations, signaling and coding. This research helps in computational biology to map the genomic information in graphical ways with clear conceptions. Adequate experimental comparisons as well as analysis established the claims with tables and graphs.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literatur
Zurück zum Zitat Abubucker S et al (2012) Metabolic reconstruction for metagenomic data and its application to the human microbiome. PLoS Comput Biol 8:e1002358CrossRef Abubucker S et al (2012) Metabolic reconstruction for metagenomic data and its application to the human microbiome. PLoS Comput Biol 8:e1002358CrossRef
Zurück zum Zitat Ayyala DN, Lin S (2015) GrammR: graphical representation and modeling of count data with application in metagenomics. Bioinformatics 31(10):1648–1654CrossRef Ayyala DN, Lin S (2015) GrammR: graphical representation and modeling of count data with application in metagenomics. Bioinformatics 31(10):1648–1654CrossRef
Zurück zum Zitat Basford KE, McLachlan GJ, Rathnayake SI (2013) On the classification of microarray gene-expression data. Brief Bioinform 14(4):402–410CrossRef Basford KE, McLachlan GJ, Rathnayake SI (2013) On the classification of microarray gene-expression data. Brief Bioinform 14(4):402–410CrossRef
Zurück zum Zitat Bazinet A, Cummings M (2012) A comparative evaluation of sequence classification programs. BMC Bioinform 13:1–13CrossRef Bazinet A, Cummings M (2012) A comparative evaluation of sequence classification programs. BMC Bioinform 13:1–13CrossRef
Zurück zum Zitat Besemer J, Borodovsky M (1999) Heuristic approach to deriving models for gene finding. Nucleic Acids Res 27(19):3911–3920CrossRef Besemer J, Borodovsky M (1999) Heuristic approach to deriving models for gene finding. Nucleic Acids Res 27(19):3911–3920CrossRef
Zurück zum Zitat Bicego M, Lovato P, Perina A, Fasoli M, Delledonne M, Pezzotti M et al (2012) Investigating topic models’ capabilities in expression microarray data classification. IEEE/ACM Trans Comput Biol Bioinform (TCBB) 9(6):1831–1836CrossRef Bicego M, Lovato P, Perina A, Fasoli M, Delledonne M, Pezzotti M et al (2012) Investigating topic models’ capabilities in expression microarray data classification. IEEE/ACM Trans Comput Biol Bioinform (TCBB) 9(6):1831–1836CrossRef
Zurück zum Zitat Bolger AM, Lohse M, Usadel B (2014) Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics 30:2114–2120CrossRef Bolger AM, Lohse M, Usadel B (2014) Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics 30:2114–2120CrossRef
Zurück zum Zitat Bolón-Canedo V, Sánchez-Maroño N, Alonso-Betanzos A (2012) An ensemble of filters and classifiers for microarray data classification. Pattern Recogn 45(1):531–539CrossRef Bolón-Canedo V, Sánchez-Maroño N, Alonso-Betanzos A (2012) An ensemble of filters and classifiers for microarray data classification. Pattern Recogn 45(1):531–539CrossRef
Zurück zum Zitat Brown CT (2015) Strain recovery from metagenomes. Nat Biotechnol 33:1041–1043CrossRef Brown CT (2015) Strain recovery from metagenomes. Nat Biotechnol 33:1041–1043CrossRef
Zurück zum Zitat Brown CT, Hug LA, Thomas BC, Sharon I, Castelle CJ, Singh A et al (2015) Unusual biology across a group comprising more than 15% of domain bacteria. Nature 523:208–211CrossRef Brown CT, Hug LA, Thomas BC, Sharon I, Castelle CJ, Singh A et al (2015) Unusual biology across a group comprising more than 15% of domain bacteria. Nature 523:208–211CrossRef
Zurück zum Zitat Brum JR, Ignacio-Espinoza JC, Roux S, Doulcier G, Acinas SG, Alberti A, Chaffron S, Cruaud C, de Vargas C, Gasol JM et al (2015) Ocean plankton. Patterns and ecological drivers of ocean viral communities. Science 348:1261498CrossRef Brum JR, Ignacio-Espinoza JC, Roux S, Doulcier G, Acinas SG, Alberti A, Chaffron S, Cruaud C, de Vargas C, Gasol JM et al (2015) Ocean plankton. Patterns and ecological drivers of ocean viral communities. Science 348:1261498CrossRef
Zurück zum Zitat Chang Z et al (2015a) Bridger: a new framework for de novo transcriptome assembly using RNA-seq data. Genome Biol 16:30CrossRef Chang Z et al (2015a) Bridger: a new framework for de novo transcriptome assembly using RNA-seq data. Genome Biol 16:30CrossRef
Zurück zum Zitat Chang Z, Li G, Li J, Zhang Y, Ashby C, Liu D, Cramer C, Huang X (2015b) Bridger: a new framework for de novo transcriptome assembly using RNA-seq data. Genome Biol 16:30CrossRef Chang Z, Li G, Li J, Zhang Y, Ashby C, Liu D, Cramer C, Huang X (2015b) Bridger: a new framework for de novo transcriptome assembly using RNA-seq data. Genome Biol 16:30CrossRef
Zurück zum Zitat Chopra P, Lee J, Kang J, Lee S (2010) Improving cancer classification accuracy using gene pairs. PLoS One 5(12):e14305CrossRef Chopra P, Lee J, Kang J, Lee S (2010) Improving cancer classification accuracy using gene pairs. PLoS One 5(12):e14305CrossRef
Zurück zum Zitat De Cruz P, Kang S, Wagner J, Buckley M, Sim WH, Prideaux L et al (2015) Association between specific mucosa-associated microbiota in Crohn’s disease at the time of resection and subsequent disease recurrence: a pilot study. J Gastroenterol Hepatol 30:268–278CrossRef De Cruz P, Kang S, Wagner J, Buckley M, Sim WH, Prideaux L et al (2015) Association between specific mucosa-associated microbiota in Crohn’s disease at the time of resection and subsequent disease recurrence: a pilot study. J Gastroenterol Hepatol 30:268–278CrossRef
Zurück zum Zitat De Vargas C, Audic S, Henry N, Decelle J, Mahé F, Logares R, Lara E, Berney C, Le Bescot N, Probert I et al (2015) Ocean plankton. Eukaryotic plankton diversity in the sunlit ocean. Science 348:1261605CrossRef De Vargas C, Audic S, Henry N, Decelle J, Mahé F, Logares R, Lara E, Berney C, Le Bescot N, Probert I et al (2015) Ocean plankton. Eukaryotic plankton diversity in the sunlit ocean. Science 348:1261605CrossRef
Zurück zum Zitat Deng X, Naccache SN, Ng T, Federman S, Li L, Chiu CY et al (2015) An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next-generation sequencing data. Nucleic Acids Res 43(7):e46CrossRef Deng X, Naccache SN, Ng T, Federman S, Li L, Chiu CY et al (2015) An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next-generation sequencing data. Nucleic Acids Res 43(7):e46CrossRef
Zurück zum Zitat Eikmeyer FG, Rademacher A, Hanreich A, Hennig M, Jaenicke S, Maus I, Wibberg D, Zakrzewski M, Pühler A, Klocke M (2013) Detailed analysis of metagenome datasets obtained from biogas-producing microbial communities residing in biogas reactors does not indicate the presence of putative pathogenic microorganisms. Biotechnol Biofuels 6(1):49CrossRef Eikmeyer FG, Rademacher A, Hanreich A, Hennig M, Jaenicke S, Maus I, Wibberg D, Zakrzewski M, Pühler A, Klocke M (2013) Detailed analysis of metagenome datasets obtained from biogas-producing microbial communities residing in biogas reactors does not indicate the presence of putative pathogenic microorganisms. Biotechnol Biofuels 6(1):49CrossRef
Zurück zum Zitat Forster SC, Lawley TD (2015) Systematic discovery of probiotics. Nat Biotechnol 33:47–49CrossRef Forster SC, Lawley TD (2015) Systematic discovery of probiotics. Nat Biotechnol 33:47–49CrossRef
Zurück zum Zitat Franzosa EA et al (2014) Relating the metatranscriptome and metagenome of the human gut. Proc Natl Acad Sci USA 111:E2329–E2338CrossRef Franzosa EA et al (2014) Relating the metatranscriptome and metagenome of the human gut. Proc Natl Acad Sci USA 111:E2329–E2338CrossRef
Zurück zum Zitat Gibbons SM, Schwartz T, Fouquier J, Mitchell M, Sangwan N, Gilbert JA et al (2015) Ecological succession and viability of human-associated microbiota on restroom surfaces. Appl Environ Microbiol 81:765–773CrossRef Gibbons SM, Schwartz T, Fouquier J, Mitchell M, Sangwan N, Gilbert JA et al (2015) Ecological succession and viability of human-associated microbiota on restroom surfaces. Appl Environ Microbiol 81:765–773CrossRef
Zurück zum Zitat Giugno R, Pulvirenti A, Cascione L, Pigola G, Ferro A (2013) MIDClass: microarray data classification by association rules and gene expression intervals. PLoS One 8(8):e69873CrossRef Giugno R, Pulvirenti A, Cascione L, Pigola G, Ferro A (2013) MIDClass: microarray data classification by association rules and gene expression intervals. PLoS One 8(8):e69873CrossRef
Zurück zum Zitat Hernandez D (2008) De novo bacterial genome sequencing: millions of very short reads assembled on a desktop computer. Genome Res 18:802–809CrossRef Hernandez D (2008) De novo bacterial genome sequencing: millions of very short reads assembled on a desktop computer. Genome Res 18:802–809CrossRef
Zurück zum Zitat Hoff KJ, Lingner T, Meinicke P, Tech M (2009) Orphelia: predicting genes in metagenomic sequencing reads. Nucleic Acids Res 37:W101–W105 (Web Server) CrossRef Hoff KJ, Lingner T, Meinicke P, Tech M (2009) Orphelia: predicting genes in metagenomic sequencing reads. Nucleic Acids Res 37:W101–W105 (Web Server) CrossRef
Zurück zum Zitat Hsiao A, Ahmed AM, Subramanian S, Griffin NW, Drewry LL, Petri WA Jr, Haque R, Ahmed T, Gordon JI (2014) Members of the human gut microbiota involved in recovery from Vibrio cholerae infection. Nature 515:423–426CrossRef Hsiao A, Ahmed AM, Subramanian S, Griffin NW, Drewry LL, Petri WA Jr, Haque R, Ahmed T, Gordon JI (2014) Members of the human gut microbiota involved in recovery from Vibrio cholerae infection. Nature 515:423–426CrossRef
Zurück zum Zitat Huang K, Brady A, Mahurkar A, White O, Gevers D, Huttenhower C, Segata N (2014) MetaRef: a pan-genomic database for comparative and community microbial genomics. Nucleic Acids Res 42:D617–D624CrossRef Huang K, Brady A, Mahurkar A, White O, Gevers D, Huttenhower C, Segata N (2014) MetaRef: a pan-genomic database for comparative and community microbial genomics. Nucleic Acids Res 42:D617–D624CrossRef
Zurück zum Zitat Hultman J, Waldrop MP, Mackelprang R, David MM, McFarland J, Blazewicz SJ et al (2015) Multi-omics of permafrost, active layer and thermokarst bog soil microbiomes. Nature 521:208–212CrossRef Hultman J, Waldrop MP, Mackelprang R, David MM, McFarland J, Blazewicz SJ et al (2015) Multi-omics of permafrost, active layer and thermokarst bog soil microbiomes. Nature 521:208–212CrossRef
Zurück zum Zitat Hunter S, Corbett M, Denise H, Fraser M, Gonzalez-Beltran A, Hunter C, Jones P, Leinonen R, McAnulla C, Maguire E et al (2014) EBI metagenomics—a new resource for the analysis and archiving of metagenomic data. Nucleic Acids Res 42:D600–D606CrossRef Hunter S, Corbett M, Denise H, Fraser M, Gonzalez-Beltran A, Hunter C, Jones P, Leinonen R, McAnulla C, Maguire E et al (2014) EBI metagenomics—a new resource for the analysis and archiving of metagenomic data. Nucleic Acids Res 42:D600–D606CrossRef
Zurück zum Zitat Huson DH et al (2011) Integrative analysis of environmental sequences using MEGAN4. Genome Res 21:1552–1560CrossRef Huson DH et al (2011) Integrative analysis of environmental sequences using MEGAN4. Genome Res 21:1552–1560CrossRef
Zurück zum Zitat Ives Z, Alon Y, Mork P, Tatarinov I (2004) Piazza: mediation and integration infrastructure for semantic web data. J Web Sem 1(2):155–175CrossRef Ives Z, Alon Y, Mork P, Tatarinov I (2004) Piazza: mediation and integration infrastructure for semantic web data. J Web Sem 1(2):155–175CrossRef
Zurück zum Zitat Jing X-Y, Zhang D, Tang Y-Y (2004) An improved LDA approach. IEEE Trans Syst Man Cybern B Cybern 34(5):1942–1951CrossRef Jing X-Y, Zhang D, Tang Y-Y (2004) An improved LDA approach. IEEE Trans Syst Man Cybern B Cybern 34(5):1942–1951CrossRef
Zurück zum Zitat Kang DD, Froula J, Egan R, Wang Z (2015) MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities. PeerJ 3:e1165CrossRef Kang DD, Froula J, Egan R, Wang Z (2015) MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities. PeerJ 3:e1165CrossRef
Zurück zum Zitat Kopf A, Bicak M, Kottmann R, Schnetzer J, Kostadinov I, Lehmann K, Fernandez-Guerra A, Jeanthon C, Rahav E, Ullrich M et al (2015) The ocean sampling day consortium. Gigascience 4:27CrossRef Kopf A, Bicak M, Kottmann R, Schnetzer J, Kostadinov I, Lehmann K, Fernandez-Guerra A, Jeanthon C, Rahav E, Ullrich M et al (2015) The ocean sampling day consortium. Gigascience 4:27CrossRef
Zurück zum Zitat Leung Y, Hung Y (2010) A multiple-filter-multiple-wrapper approach to gene selection and microarray data classification. IEEE/ACM Trans Comput Biol Bioinform (TCBB) 7(1):108–117CrossRef Leung Y, Hung Y (2010) A multiple-filter-multiple-wrapper approach to gene selection and microarray data classification. IEEE/ACM Trans Comput Biol Bioinform (TCBB) 7(1):108–117CrossRef
Zurück zum Zitat Leimena MM et al (2013) A comprehensive metatranscriptome analysis pipeline and its validation using human small intestine microbiota datasets. BMC Genom 14:530CrossRef Leimena MM et al (2013) A comprehensive metatranscriptome analysis pipeline and its validation using human small intestine microbiota datasets. BMC Genom 14:530CrossRef
Zurück zum Zitat Lima-Mendez G, Faust K, Henry N, Decelle J, Colin S, Carcillo F, Chaffron S, Ignacio-Espinosa JC, Roux S, Vincent F et al (2015) Ocean plankton. Determinants of community structure in the global plankton interactome. Science 348(6237):1262073 Lima-Mendez G, Faust K, Henry N, Decelle J, Colin S, Carcillo F, Chaffron S, Ignacio-Espinosa JC, Roux S, Vincent F et al (2015) Ocean plankton. Determinants of community structure in the global plankton interactome. Science 348(6237):1262073
Zurück zum Zitat Liu H, Liu L, Zhang H (2010a) Ensemble gene selection by grouping for microarray data classification. J Biomed Inform 43(1):81–87CrossRef Liu H, Liu L, Zhang H (2010a) Ensemble gene selection by grouping for microarray data classification. J Biomed Inform 43(1):81–87CrossRef
Zurück zum Zitat Liu H, Liu L, Zhang H (2010b) Ensemble gene selection for cancer classification. Pattern Recogn 43(8):2763–2772CrossRef Liu H, Liu L, Zhang H (2010b) Ensemble gene selection for cancer classification. Pattern Recogn 43(8):2763–2772CrossRef
Zurück zum Zitat Lozupone C, Lladser ME, Knights D, Stombaugh J, Knight R (2011) UniFrac: an effective distance metric for microbial community comparison. ISME J 5(2):169–172CrossRef Lozupone C, Lladser ME, Knights D, Stombaugh J, Knight R (2011) UniFrac: an effective distance metric for microbial community comparison. ISME J 5(2):169–172CrossRef
Zurück zum Zitat Lenzerini M (2002) Data integration: a theoretical perspective. Proc ACM PODS, Madison, WI, pp 233–246 Lenzerini M (2002) Data integration: a theoretical perspective. Proc ACM PODS, Madison, WI, pp 233–246
Zurück zum Zitat Lu H, Qian G, Ren Z et al (2015) Alterations of Bacteroides sp., Neisseria sp., Actinomyces sp., and Streptococcus sp. populations in the oropharyngeal microbiome are associated with liver cirrhosis and pneumonia. BMC Infect Dis 15(1):239CrossRef Lu H, Qian G, Ren Z et al (2015) Alterations of Bacteroides sp., Neisseria sp., Actinomyces sp., and Streptococcus sp. populations in the oropharyngeal microbiome are associated with liver cirrhosis and pneumonia. BMC Infect Dis 15(1):239CrossRef
Zurück zum Zitat Markowitz VM, Chen IM, Palaniappan K, Chu K, Szeto E, Pillay M, Ratner A, Huang J, Woyke T, Huntemann M et al (2014) IMG 4 version of the integrated microbial genomes comparative analysis system. Nucleic Acids Res 42:D560–D567CrossRef Markowitz VM, Chen IM, Palaniappan K, Chu K, Szeto E, Pillay M, Ratner A, Huang J, Woyke T, Huntemann M et al (2014) IMG 4 version of the integrated microbial genomes comparative analysis system. Nucleic Acids Res 42:D560–D567CrossRef
Zurück zum Zitat Maurice CF, Haiser HJ, Turnbaugh PJ (2013) Xenobiotics shape the physiology and gene expression of the active human gut microbiome. Cell 152(1–2):39–50CrossRef Maurice CF, Haiser HJ, Turnbaugh PJ (2013) Xenobiotics shape the physiology and gene expression of the active human gut microbiome. Cell 152(1–2):39–50CrossRef
Zurück zum Zitat McNulty NP et al (2011) The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med 3(106):ra106CrossRef McNulty NP et al (2011) The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med 3(106):ra106CrossRef
Zurück zum Zitat Meyer F et al (2008) The metagenomics RAST server—a public resource for the automatic phylogenetic and functional analysis of metagenomes. BMC Bioinform 9:386CrossRef Meyer F et al (2008) The metagenomics RAST server—a public resource for the automatic phylogenetic and functional analysis of metagenomes. BMC Bioinform 9:386CrossRef
Zurück zum Zitat Mitchell A, Chang H-Y, Daugherty L, Fraser M, Hunter S, Lopez R, McAnulla C, McMenamin C, Nuka G, Pesseat S et al (2015) The InterPro protein families database: the classification resource after 15 years. Nucleic Acids Res 43:D213–D221CrossRef Mitchell A, Chang H-Y, Daugherty L, Fraser M, Hunter S, Lopez R, McAnulla C, McMenamin C, Nuka G, Pesseat S et al (2015) The InterPro protein families database: the classification resource after 15 years. Nucleic Acids Res 43:D213–D221CrossRef
Zurück zum Zitat Mochizuki H, Nakamura K, Sato H, Goto-Koshino Y, Sato M, Takahashi M, Fujino Y, Ohno K (2011) Multiplex PCR and Genescan analysis to detect immunoglobulin heavy chain gene rearrangement in feline B-cell neoplasms. Vet Immunol Immunopathol 143(2011):38–45CrossRef Mochizuki H, Nakamura K, Sato H, Goto-Koshino Y, Sato M, Takahashi M, Fujino Y, Ohno K (2011) Multiplex PCR and Genescan analysis to detect immunoglobulin heavy chain gene rearrangement in feline B-cell neoplasms. Vet Immunol Immunopathol 143(2011):38–45CrossRef
Zurück zum Zitat Noguchi H, Park J, Takagi T (2006) MetaGene: prokaryotic gene finding from environmental genome shotgun sequences. Nucleic Acids Res 34(19):5623–5630CrossRef Noguchi H, Park J, Takagi T (2006) MetaGene: prokaryotic gene finding from environmental genome shotgun sequences. Nucleic Acids Res 34(19):5623–5630CrossRef
Zurück zum Zitat Noguchi H, Taniguchi T, Itoh T (2008) Meta gene annotator: detecting species-specific patterns of ribosomal binding site for precise gene prediction in anonymous prokaryotic and phage genomes. DNA Res 15(6):387–396CrossRef Noguchi H, Taniguchi T, Itoh T (2008) Meta gene annotator: detecting species-specific patterns of ribosomal binding site for precise gene prediction in anonymous prokaryotic and phage genomes. DNA Res 15(6):387–396CrossRef
Zurück zum Zitat Li P, Yang C, Xie J et al (2015) Acinetobacter calcoaceticus from a fatal case of pneumonia harboring blaNDM-1 on a widely distributed plasmid. BMC Infect Dis 15(131) Li P, Yang C, Xie J et al (2015) Acinetobacter calcoaceticus from a fatal case of pneumonia harboring blaNDM-1 on a widely distributed plasmid. BMC Infect Dis 15(131)
Zurück zum Zitat Parra G, Blanco E, Guigo R (2000) GeneID in Drosophila. Genome Res 10:511–515CrossRef Parra G, Blanco E, Guigo R (2000) GeneID in Drosophila. Genome Res 10:511–515CrossRef
Zurück zum Zitat Carreira P, Helena G (2004) Execution of data mappers. Proc ACM SIGMOD workshop IQIS, Paris, France, pp 2–9 Carreira P, Helena G (2004) Execution of data mappers. Proc ACM SIGMOD workshop IQIS, Paris, France, pp 2–9
Zurück zum Zitat Pylro VS, Roesch L, Ortega JM, do Amaral AM (2014) Brazilian microbiome project: revealing the unexplored microbial diversity challenges and prospects. Microb Ecol 67:237–241. doi:10.1007/s00248-013-0302-4 CrossRef Pylro VS, Roesch L, Ortega JM, do Amaral AM (2014) Brazilian microbiome project: revealing the unexplored microbial diversity challenges and prospects. Microb Ecol 67:237–241. doi:10.​1007/​s00248-013-0302-4 CrossRef
Zurück zum Zitat Raman V, Joseph MH (2001) Potter’s Wheel: an interactive data cleaning system. Proc VLDB Conf, Roma, Italy, pp 381–390 Raman V, Joseph MH (2001) Potter’s Wheel: an interactive data cleaning system. Proc VLDB Conf, Roma, Italy, pp 381–390
Zurück zum Zitat Reboiro-Jato M, Arrais JP, Oliveira JL, Fdez-Riverola F (2014) geneCommittee: a web-based tool for extensively testing the discriminatory power of biologically relevant gene sets in microarray data classification. BMC Bioinform 15(1):31CrossRef Reboiro-Jato M, Arrais JP, Oliveira JL, Fdez-Riverola F (2014) geneCommittee: a web-based tool for extensively testing the discriminatory power of biologically relevant gene sets in microarray data classification. BMC Bioinform 15(1):31CrossRef
Zurück zum Zitat Reddy TBK, Thomas AD, Stamatis D, Bertsch J, Isbandi M, Jansson J, Mallajosyula J, Pagani I, Lobos EA, Kyrpides NC (2015) The Genomes OnLine Database (GOLD) v. 5: a metadata management system based on a four level (meta)genome project classification. Nucleic Acids Res 43:D1099–D1106CrossRef Reddy TBK, Thomas AD, Stamatis D, Bertsch J, Isbandi M, Jansson J, Mallajosyula J, Pagani I, Lobos EA, Kyrpides NC (2015) The Genomes OnLine Database (GOLD) v. 5: a metadata management system based on a four level (meta)genome project classification. Nucleic Acids Res 43:D1099–D1106CrossRef
Zurück zum Zitat Rusch DB, Halpern AL, Sutton G, Heidelberg KB, Williamson S, Yooseph S, Wu D, Eisen JA, Hoffman JM, Remington K et al (2007) The Sorcerer II global ocean sampling expedition: northwest Atlantic through eastern tropical Pacific. PLoS Biol 5:e77CrossRef Rusch DB, Halpern AL, Sutton G, Heidelberg KB, Williamson S, Yooseph S, Wu D, Eisen JA, Hoffman JM, Remington K et al (2007) The Sorcerer II global ocean sampling expedition: northwest Atlantic through eastern tropical Pacific. PLoS Biol 5:e77CrossRef
Zurück zum Zitat Sangwan N, Xia F, Gilbert JA (2016) Recovering complete and draft population genomes from metagenome datasets. Microbiome 4:8CrossRef Sangwan N, Xia F, Gilbert JA (2016) Recovering complete and draft population genomes from metagenome datasets. Microbiome 4:8CrossRef
Zurück zum Zitat Sato K, Sakakibara Y (2015) MetaVelvet-SL: an extension of the Velvet assembler to a de novo metagenomic assembler utilizing supervised learning. DNA Res 22(1):69–77CrossRef Sato K, Sakakibara Y (2015) MetaVelvet-SL: an extension of the Velvet assembler to a de novo metagenomic assembler utilizing supervised learning. DNA Res 22(1):69–77CrossRef
Zurück zum Zitat Schlüter A, Bekel T, Diaz NN, Dondrup M, Eichenlaub R, Gartemann K-H, Krahn I, Krause L, Krömeke H, Kruse O (2008) The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technology. J Biotechnol 136(1):77–90CrossRef Schlüter A, Bekel T, Diaz NN, Dondrup M, Eichenlaub R, Gartemann K-H, Krahn I, Krause L, Krömeke H, Kruse O (2008) The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technology. J Biotechnol 136(1):77–90CrossRef
Zurück zum Zitat Sharma VK, Kumar N, Prakash T, Taylor TD (2010) MetaBioME: a database to explore commercially useful enzymes in metagenomic datasets. Nucleic Acids Res 38:D468–D472CrossRef Sharma VK, Kumar N, Prakash T, Taylor TD (2010) MetaBioME: a database to explore commercially useful enzymes in metagenomic datasets. Nucleic Acids Res 38:D468–D472CrossRef
Zurück zum Zitat Silvester N, Alako B, Amid C, Cerdeno-Tarraga A, Cleland I, Gibson R, Goodgame N, Ten Hoopen P, Kay S, Leinonen R et al (2015) Content discovery and retrieval services at the European Nucleotide Archive. Nucleic Acids Res 43:D23–D29CrossRef Silvester N, Alako B, Amid C, Cerdeno-Tarraga A, Cleland I, Gibson R, Goodgame N, Ten Hoopen P, Kay S, Leinonen R et al (2015) Content discovery and retrieval services at the European Nucleotide Archive. Nucleic Acids Res 43:D23–D29CrossRef
Zurück zum Zitat Sunagawa S, Coelho LP, Chaffron S, Kultima JR, Labadie K, Salazar G, Djahanschiri B, Zeller G, Mende DR, Alberti A et al (2015) Ocean plankton. Structure and function of the global ocean microbiome. Science 348:1261359CrossRef Sunagawa S, Coelho LP, Chaffron S, Kultima JR, Labadie K, Salazar G, Djahanschiri B, Zeller G, Mende DR, Alberti A et al (2015) Ocean plankton. Structure and function of the global ocean microbiome. Science 348:1261359CrossRef
Zurück zum Zitat Freitas TAK, Li PE, Scholz MB, Chain PSG (2015) Accurate read-based metagenome characterization using a hierarchical suite of unique signatures. Nucleic Acids Res 1. doi:10.1093/nar/gkv180 Freitas TAK, Li PE, Scholz MB, Chain PSG (2015) Accurate read-based metagenome characterization using a hierarchical suite of unique signatures. Nucleic Acids Res 1. doi:10.​1093/​nar/​gkv180
Zurück zum Zitat Ten Hoopen P, Pesant S, Kottmann R, Kopf A, Bicak M, Claus S, Deneudt K, Borremans C, Thijsse P, Dekeyzer S et al (2015) Marine microbial biodiversity, bioinformatics and biotechnology (M2B3) data reporting and service standards. Stand Genomic Sci. 10:20CrossRef Ten Hoopen P, Pesant S, Kottmann R, Kopf A, Bicak M, Claus S, Deneudt K, Borremans C, Thijsse P, Dekeyzer S et al (2015) Marine microbial biodiversity, bioinformatics and biotechnology (M2B3) data reporting and service standards. Stand Genomic Sci. 10:20CrossRef
Zurück zum Zitat Villar E, Farrant GK, Follows M, Garczarek L, Speich S, Audic S, Bittner L, Blanke B, Brum JR, Brunet C et al (2015) Ocean plankton. Environmental characteristics of Agulhas rings affect interocean plankton transport. Science 348:1261447CrossRef Villar E, Farrant GK, Follows M, Garczarek L, Speich S, Audic S, Bittner L, Blanke B, Brum JR, Brunet C et al (2015) Ocean plankton. Environmental characteristics of Agulhas rings affect interocean plankton transport. Science 348:1261447CrossRef
Zurück zum Zitat Wang S, Cho H, Zhai CX, Berger B, Peng J (2015) Exploiting ontology graph for predicting sparsely annotated gene function. Bioinformatics 31:i357–i364CrossRef Wang S, Cho H, Zhai CX, Berger B, Peng J (2015) Exploiting ontology graph for predicting sparsely annotated gene function. Bioinformatics 31:i357–i364CrossRef
Zurück zum Zitat Wirth R, Kovács E, Maróti G, Bagi Z, Rákhely G, Kovács KL (2012) Characterization of a biogas-producing microbial community by short-read next generation DNA sequencing. Biotechnol Biofuels 5(1):41CrossRef Wirth R, Kovács E, Maróti G, Bagi Z, Rákhely G, Kovács KL (2012) Characterization of a biogas-producing microbial community by short-read next generation DNA sequencing. Biotechnol Biofuels 5(1):41CrossRef
Zurück zum Zitat Wu MY, Dai DQ, Shi Y, Yan H, Zhang XF (2012) Biomarker identification and cancer classification based on microarray data using laplace naive Bayes model with mean shrinkage. IEEE/ACM Trans Comput Biol Bioinform (TCBB) 9(6):1649–1662CrossRef Wu MY, Dai DQ, Shi Y, Yan H, Zhang XF (2012) Biomarker identification and cancer classification based on microarray data using laplace naive Bayes model with mean shrinkage. IEEE/ACM Trans Comput Biol Bioinform (TCBB) 9(6):1649–1662CrossRef
Zurück zum Zitat Wu Y-W, Simmons BA, Singer SW (2016) MaxBin 2.0: an automated binning algorithm to recover genomes from multiple metagenomic datasets. Bioinformatics 32(4):605–607CrossRef Wu Y-W, Simmons BA, Singer SW (2016) MaxBin 2.0: an automated binning algorithm to recover genomes from multiple metagenomic datasets. Bioinformatics 32(4):605–607CrossRef
Zurück zum Zitat Xu K, Cui J, Olman V, Yang Q, Puett D, Xu Y (2010) A comparative analysis of gene-expression data of multiple cancer types. PLoS One 5(10):e13696CrossRef Xu K, Cui J, Olman V, Yang Q, Puett D, Xu Y (2010) A comparative analysis of gene-expression data of multiple cancer types. PLoS One 5(10):e13696CrossRef
Zurück zum Zitat Rahm E, Philip A (2001) A survey of approaches to automatic schema matching. VLDB J 10(4):334–350CrossRefMATH Rahm E, Philip A (2001) A survey of approaches to automatic schema matching. VLDB J 10(4):334–350CrossRefMATH
Zurück zum Zitat Wang Y, Li R, Zhou Y, Ling Z, Guo X, Xie L, Liu L (2016) Motif-based text mining of microbial metagenome redundancy profiling data for disease classification. BioMed Res Int 2016: 11 pages (Article ID 6598307) Wang Y, Li R, Zhou Y, Ling Z, Guo X, Xie L, Liu L (2016) Motif-based text mining of microbial metagenome redundancy profiling data for disease classification. BioMed Res Int 2016: 11 pages (Article ID 6598307)
Zurück zum Zitat Yinan W, Renner DW, Albert I, Szpara ML (2015) VirAmp: a galaxy-based viral genome assembly pipeline. GigaScience 4:19CrossRef Yinan W, Renner DW, Albert I, Szpara ML (2015) VirAmp: a galaxy-based viral genome assembly pipeline. GigaScience 4:19CrossRef
Zurück zum Zitat Yuzhen Y, Haixu T (2015) Utilizing de Bruijn graph of metagenome assembly for metatranscriptome analysis. Bioinformatics 32(7):1001–1008 Yuzhen Y, Haixu T (2015) Utilizing de Bruijn graph of metagenome assembly for metatranscriptome analysis. Bioinformatics 32(7):1001–1008
Metadaten
Titel
MetaG: a graph-based metagenomic gene analysis for big DNA data
verfasst von
Linkon Chowdhury
Mohammad Ibrahim Khan
Kaushik Deb
Sarwar Kamal
Publikationsdatum
01.12.2016
Verlag
Springer Vienna
Erschienen in
Network Modeling Analysis in Health Informatics and Bioinformatics / Ausgabe 1/2016
Print ISSN: 2192-6662
Elektronische ISSN: 2192-6670
DOI
https://doi.org/10.1007/s13721-016-0132-7

Weitere Artikel der Ausgabe 1/2016

Network Modeling Analysis in Health Informatics and Bioinformatics 1/2016 Zur Ausgabe

Premium Partner