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Erschienen in:
2014 | OriginalPaper | Buchkapitel
Modeling of Membrane Proteins
verfasst von : Dorota Latek, Bartosz Trzaskowski, Szymon Niewieczerzał, Przemysław Miszta, Krzysztof Młynarczyk, Aleksander Debinski, Wojciech Puławski, Shuguang Yuan, Sławomir Filipek
Erschienen in: Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes
Verlag: Springer Berlin Heidelberg
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The membrane proteins are still the “Wild West” of structural biology. Although more and more membrane proteins structures are determined, their functioning is still difficult to investigate because they are fully functional only in the membranous environments. Several specific methodologies were developed to investigate various aspects of their cellular life but still they are challenging for computational methods. In this chapter we summarize the efforts made on elucidation the structural and dynamical properties of different types of membrane proteins emphasizing on those computational methods which were designed and employed particularly to study membrane proteins including their interactions in complex membranous systems.