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2003 | OriginalPaper | Buchkapitel

Parametric Empirical Bayes Methods for Microarrays

verfasst von : Michael A. Newton, Christina Kendziorski

Erschienen in: The Analysis of Gene Expression Data

Verlag: Springer New York

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We have developed an empirical Bayes methodology for gene expression data to account for replicate arrays, multiple conditions, and a range of modeling assumptions. The methodology is implemented in an R library called EBarrays. Functions in the library calculate posterior probabilities of patterns of differential expression across multiple conditions. This chapter provides an overview of the methodology and its implementation in EBarrays.

Metadaten
Titel
Parametric Empirical Bayes Methods for Microarrays
verfasst von
Michael A. Newton
Christina Kendziorski
Copyright-Jahr
2003
Verlag
Springer New York
DOI
https://doi.org/10.1007/0-387-21679-0_11