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Erschienen in: Journal of Nanoparticle Research 12/2012

01.12.2012 | Research Paper

Preparation of cytocompatible luminescent and magnetic nanohybrids based on ZnO, Zn0.95Ni0.05O and core@shell ZnO@Fe2O3 polymer grafted nanoparticles for biomedical imaging

verfasst von: I. Balti, A. Barrère, V. Gueguen, L. Poussard, G. Pavon-Djavid, A. Meddahi-Pellé, P. Rabu, L. S. Smiri, N. Jouini, F. Chaubet

Erschienen in: Journal of Nanoparticle Research | Ausgabe 12/2012

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Abstract

ZnO, Zn0.95Ni0.05O and core@shell ZnO@γ-Fe2O3 nanoparticles (NPs) have been prepared by forced hydrolysis in polyol medium and then coated via the “grafting from” approach with poly(sodium-4-styrenesulfonate) and poly(sodium-4-styrenesulfonate–co–sodium methacrylate) in the case of ZnO. The surface-initiated atom transfer radical polymerization occurred from the surface-functionalized NPs with α-bromoisobutyric acid as initiator. The polymer chains were grown from the surface to yield hybrid NPs with a 1–3-nm thick organic shell. FT-IR, TGA and electron microscopy evidenced the presence of a polymer layer on the surface of NPs. Magnetic and optical properties of bare and coated NPs have been measured. Eventually, the weak cytotoxicity of coated NPs on human endothelial cell allows considering their potentialities as new tools for nanomedicine and biomedical imaging.

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Metadaten
Titel
Preparation of cytocompatible luminescent and magnetic nanohybrids based on ZnO, Zn0.95Ni0.05O and core@shell ZnO@Fe2O3 polymer grafted nanoparticles for biomedical imaging
verfasst von
I. Balti
A. Barrère
V. Gueguen
L. Poussard
G. Pavon-Djavid
A. Meddahi-Pellé
P. Rabu
L. S. Smiri
N. Jouini
F. Chaubet
Publikationsdatum
01.12.2012
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 12/2012
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-012-1266-x

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