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Erschienen in:
2011 | OriginalPaper | Buchkapitel
2. Principles of Inheritance: Mendel’s Laws and Genetic Models
verfasst von : Nan M. Laird, Christoph Lange
Erschienen in: The Fundamentals of Modern Statistical Genetics
Verlag: Springer New York
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Abstract
It is difficult to overstate the impact of Mendel’s research on the history of genetics; indeed, his research in genetics has been credited as one of the great experimental advances in biology (Fisher, 1965). Prior to the publication of his results on experimental hybridization in plants, the concept of inheritance of physical ‘units’ (later called genes) was accepted, and scientists had reported on many hybridization experiments in both animals and plants. Yet no one had set forth principles of inheritance which could be used as a universal theory to explain how traits in offspring can be predicted from traits in the parents. Mendel provided an explicit rule for how the genotypes of the offspring can be predicted from the genotypes of their parents, and he also established models for how genotypes were related to traits.