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Erschienen in:
2010 | OriginalPaper | Buchkapitel
Simulation of ECG Repolarization Phase with Improved Model of Cell Action Potentials
verfasst von : Roman Trobec, Matjaž Depolli, Viktor Avbelj
Erschienen in: Biomedical Engineering Systems and Technologies
Verlag: Springer Berlin Heidelberg
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An improved model of action potentials (AP) is proposed to increase the accuracy of simulated electrocardiograms (ECGs). ECG simulator is based on a spatial model of a left ventricle, composed of cubic cells. Three distinct APs, modeled with functions proposed by Wohlfard, have been assigned to the cells, forming epicardial, mid, and endocardial layers. Identification of exact parameter values for AP models has been done through optimization of the simulated ECGs. Results have shown that only through an introduction of a minor extension to the AP model, simulator is able to produce more realistic ECGs. The same extension also proves essential for achieving a better fit between the measured and modeled APs.