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Erschienen in:
2020 | OriginalPaper | Buchkapitel
A Domain Framework Approach for Quality Feature Analysis of Genome Assemblies
verfasst von : Guilherme Borba Neumann, Elvismary Molina de Armas, Fernanda Araujo Baiao, Ruy Luiz Milidiu, Sergio Lifschitz
Erschienen in: Advances in Bioinformatics and Computational Biology
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Abstract
The Genome Assembly research area has quickly evolved, adapting to new sequencing technologies and modern computational environments. There exist many assembler software systems that consider multiple approaches; however, at the end of the process, the assembly quality can always be questioned. When an assembly is accomplished, one may generate quality features for its qualification. Nonetheless, these features do not directly explain the assembly quality; instead, they only list quantitative assembly descriptions. This work proposes GAAF (Genome Assembly Analysis Framework), a domain framework for the feature analysis post-genome Assembly process. GAAF works with distinct species, assemblers, and features, and its goal is to enable data interpretation and assembly quality evaluation.